Zobrazeno 1 - 10
of 65
pro vyhledávání: '"Till, S"'
Autor:
Simon Kind, Carolina Palacios Castillo, Ria Schlichter, Natalia Gorbokon, Maximilian Lennartz, Lisa S. Hornsteiner, Sebastian Dwertmann Rico, Viktor Reiswich, Florian Viehweger, Martina Kluth, Claudia Hube-Magg, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Christoph Fraune, Andrea Hinsch, Till Krech, Patrick Lebok, Stefan Steurer, Eike Burandt, Sarah Minner, Andreas H. Marx, Ronald Simon, Waldemar Wilczak, Guido Sauter, Anne Menz, Frank Jacobsen
Publikováno v:
BMC Cancer, Vol 24, Iss 1, Pp 1-17 (2024)
Abstract Background Kallikrein-related peptidase 7 (KLK7) is a chymotrypsin-like serine protease which is essential for the desquamation of corneocytes and thus plays a pivotal role in maintaining skin homeostasis. In cancer, KLK7 overexpression was
Externí odkaz:
https://doaj.org/article/5ac61efaf1d649688eb409482a34a7c5
Autor:
Samantha M. Meadows, Fernando Palaguachi, Minwoo Wendy Jang, Avital Licht-Murava, Daniel Barnett, Till S. Zimmer, Constance Zhou, Samantha R. McDonough, Adam L. Orr, Anna G. Orr
Publikováno v:
Cell Reports, Vol 43, Iss 6, Pp 114278- (2024)
Summary: Astrocytic receptors influence cognitive function and can promote behavioral deficits in disease. These effects may vary based on variables such as biological sex, but it is not known if the effects of astrocytic receptors are dependent on s
Externí odkaz:
https://doaj.org/article/b615039c5bc64967aff8c3199aa8fe35
Autor:
Florian Viehweger, Carola Böcker, Sören Weidemann, Morton Freytag, Anne Menz, Franziska Büscheck, Andreas M. Luebke, Devita Putri, Martina Kluth, Claudia Hube-Magg, Andrea Hinsch, Maximilian Lennartz, Florian Lutz, Viktor Reiswich, Doris Höflmayer, Christoph Fraune, Katharina Möller, Christian Bernreuther, Patrick Lebok, Guido Sauter, Stefan Steurer, David Dum, Andreas H. Marx, Ronald Simon, Till Krech, Till S. Clauditz, Frank Jacobsen, Natalia Gorbokon, Eike Burandt, Sarah Minner, Simon Kind
Publikováno v:
Diagnostic Pathology, Vol 19, Iss 1, Pp 1-13 (2024)
Abstract Background Prostein (P501S), also termed solute carrier family 45 member 3 (SLC45A3) is an androgen regulated protein which is preferentially expressed in prostate epithelial cells. Because of its frequent expression in prostate cancer, pros
Externí odkaz:
https://doaj.org/article/1ce52e7787bb496aabfb9873d8fef92f
Autor:
Aline Freville, Lindsay B. Stewart, Kevin K. A. Tetteh, Moritz Treeck, Alfred Cortes, Till S. Voss, Sarah J. Tarr, David A. Baker, David J. Conway
Publikováno v:
mBio, Vol 15, Iss 5 (2024)
ABSTRACTThe Plasmodium falciparum merozoite surface protein MSPDBL2 is a polymorphic antigen targeted by acquired immune responses, and normally expressed in only a minority of mature schizonts. The potential relationship of MSPDBL2 to sexual commitm
Externí odkaz:
https://doaj.org/article/a3c074ac2bf04bf99c760a62f54b71a2
Autor:
Anne Menz, Julia Zerneke, Florian Viehweger, Seyma Büyücek, David Dum, Ria Schlichter, Andrea Hinsch, Ahmed Abdulwahab Bawahab, Christoph Fraune, Christian Bernreuther, Martina Kluth, Claudia Hube-Magg, Katharina Möller, Florian Lutz, Viktor Reiswich, Andreas M. Luebke, Patrick Lebok, Sören A. Weidemann, Guido Sauter, Maximilian Lennartz, Frank Jacobsen, Till S. Clauditz, Andreas H. Marx, Ronald Simon, Stefan Steurer, Eike Burandt, Natalia Gorbokon, Sarah Minner, Till Krech
Publikováno v:
Cancers, Vol 16, Iss 13, p 2425 (2024)
Stimulator of interferon genes protein (STING) activates the immune response in inflammatory cells. STING expression in cancer cells is less well characterized, but STING agonists are currently being evaluated as anticancer drugs. A tissue microarray
Externí odkaz:
https://doaj.org/article/393d3931e4a845e085adea98024f1710
Autor:
Maximilian Lennartz, Henrietta Csomós, Viktoria Chirico, Sören Weidemann, Natalia Gorbokon, Anne Menz, Franziska Büscheck, Claudia Hube-Magg, Doris Höflmayer, Christian Bernreuther, Niclas C. Blessin, Patrick Lebok, Guido Sauter, Stefan Steurer, Eike Burandt, David Dum, Till Krech, Ronald Simon, Sarah Minner, Frank Jacobsen, Till S. Clauditz, Andreas M. Luebke, Abdul Khalid Siraj, Fouad Al-Dayel, Khawla S. Al-Kuraya, Andrea Hinsch
Publikováno v:
Scientific Reports, Vol 13, Iss 1, Pp 1-12 (2023)
Abstract Cadherin-16 (CDH16) plays a role in the embryonal development in kidney and thyroid. Downregulation of CDH16 RNA was found in papillary carcinomas of the thyroid. To determine the expression of CDH16 in tumors and to assess the diagnostic ut
Externí odkaz:
https://doaj.org/article/bbfd9ebdf3b84c049d5620f1b25266ec
Autor:
Anne Menz, Nora Lony, Maximilian Lennartz, Sebastian Dwertmann Rico, Ria Schlichter, Simon Kind, Viktor Reiswich, Florian Viehweger, David Dum, Andreas M. Luebke, Martina Kluth, Natalia Gorbokon, Claudia Hube-Magg, Christian Bernreuther, Ronald Simon, Till S. Clauditz, Guido Sauter, Andrea Hinsch, Frank Jacobsen, Andreas H. Marx, Stefan Steurer, Sarah Minner, Eike Burandt, Till Krech, Patrick Lebok, Sören Weidemann
Publikováno v:
Diagnostics, Vol 14, Iss 10, p 1044 (2024)
EpCAM is expressed in many epithelial tumors and is used for the distinction of malignant mesotheliomas from adenocarcinomas and as a surrogate pan-epithelial marker. A tissue microarray containing 14,832 samples from 120 different tumor categories w
Externí odkaz:
https://doaj.org/article/37a7dfa58a674ff98acd50533d86ce0c
Autor:
Florian Viehweger, Jennifer Hoop, Lisa-Marie Tinger, Christian Bernreuther, Franziska Büscheck, Till S. Clauditz, Andrea Hinsch, Frank Jacobsen, Andreas M. Luebke, Stefan Steurer, Claudia Hube-Magg, Martina Kluth, Andreas H. Marx, Till Krech, Patrick Lebok, Christoph Fraune, Eike Burandt, Guido Sauter, Ronald Simon, Sarah Minner
Publikováno v:
Biomedicines, Vol 12, Iss 5, p 957 (2024)
Androgen receptor (AR) is a transcription factor expressed in various normal tissues and is a therapeutic target for prostate and possibly other cancers. A TMA containing 18,234 samples from 141 different tumor types/subtypes and 608 samples of 76 di
Externí odkaz:
https://doaj.org/article/67466c86e8b94945acb66492eacdd01e
Autor:
Mark J. Luinenburg, Mirte Scheper, Frederik N. F. Sørensen, Jasper J. Anink, Wim Van Hecke, Irina Korshunova, Floor E. Jansen, Kate Riney, Pieter van Eijsden, Peter Gosselaar, James D. Mills, Rozemarijn S. Kalf, Till S. Zimmer, Diede W. M. Broekaart, Konstantin Khodosevich, Eleonora Aronica, Angelika Mühlebner
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 17 (2023)
IntroductionConstitutive activation of the mTOR pathway, as observed in Tuberous Sclerosis Complex (TSC), leads to glial dysfunction and subsequent epileptogenesis. Although astrocytes are considered important mediators for synaptic clearance and pha
Externí odkaz:
https://doaj.org/article/0db49681f11748d091f2555b467a7b86
Autor:
Lukas Meier, Marina Antillon, Christian Burri, Nakul Chitnis, Yvette Endriss, Jennifer Keiser, Sarah Moore, Pie Müller, Melissa Penny, Till S. Voss, Pascal Mäser, Jürg Utzinger
Publikováno v:
CHIMIA, Vol 77, Iss 9 (2023)
In pursuing novel therapeutic solutions, drug discovery and development rely on efficiently utilising existing knowledge and resources. Repurposing know-how, a strategy that capitalises on previously acquired information and expertise, has emerged as
Externí odkaz:
https://doaj.org/article/893f70b540d3482ca499ff5f9881f1c1