Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Thomas F. Schilling"'
Publikováno v:
Frontiers in Endocrinology, Vol 13 (2022)
Research on the genetic mechanisms underlying human skeletal development and disease have largely relied on studies in mice. However, recently the zebrafish has emerged as a popular model for skeletal research. Despite anatomical differences such as
Externí odkaz:
https://doaj.org/article/6a3d0d6d5cb14e158c87f4fd360d6e3e
Autor:
Laura A. Hendrick, Grace A. Carter, Erin H. Hilbrands, Brian P. Heubel, Thomas F. Schilling, Pierre Le Pabic
Publikováno v:
EvoDevo, Vol 10, Iss 1, Pp 1-18 (2019)
Abstract Background Melanic patterns such as horizontal stripes, vertical bars and spots are common among teleost fishes and often serve roles in camouflage or mimicry. Extensive research in the zebrafish model has shown that the development of horiz
Externí odkaz:
https://doaj.org/article/0773904ace0f4efa92c4e5b70d19101b
Publikováno v:
Cells, Vol 10, Iss 8, p 2005 (2021)
Aquaporin 0 (AQP0) is the most abundant lens membrane protein, and loss of function in human and animal models leads to cataract formation. AQP0 has several functions in the lens including water transport and adhesion. Since lens optics rely on stric
Externí odkaz:
https://doaj.org/article/dc90228119f74cdd9240a24d07d26077
Publikováno v:
EvoDevo, Vol 7, Iss 1, Pp 1-26 (2016)
Abstract Background Cichlid fishes from the Rift Lakes of East Africa have undergone the most spectacular adaptive radiations in vertebrate history. Eco-morphological adaptations in lakes Victoria, Malawi and Tanganyika have resulted in a vast array
Externí odkaz:
https://doaj.org/article/1ab8552e74224847877da8744a6f0cde
Abstract QS43: Blepharophimosis Ptosis Epicanthus Inversus Syndrome Caused by a ZC3H13 Gene Mutation
Autor:
Daniel M. Balkin, MD, PhD, Carol Nelson-Williams, BS, MS, Brandon J. Sumpio, BA, Daryl A. Scott, MD, PhD, Pierre Le Pabic, PhD, Thomas F. Schilling, PhD, Richard P. Lifton, MD, PhD, Deepak Narayan, MD
Publikováno v:
Plastic and Reconstructive Surgery, Global Open, Vol 6, Iss 4S, Pp 142-143 (2018)
Externí odkaz:
https://doaj.org/article/8c39f2718d30424c834d4d5e59b69810
Autor:
Thomas F Schilling, Pierre Le Pabic
Publikováno v:
eLife, Vol 11 (2022)
A newly discovered enhancer region may have allowed vertebrates to evolve the ability to open and close their jaws.
Externí odkaz:
https://doaj.org/article/7f0aadec9fa5441cb2bf097b585be15a
Publikováno v:
PLoS Computational Biology, Vol 17, Iss 6, p e1009077 (2021)
The vertebrate hindbrain is segmented into rhombomeres (r) initially defined by distinct domains of gene expression. Previous studies have shown that noise-induced gene regulation and cell sorting are critical for the sharpening of rhombomere boundar
Externí odkaz:
https://doaj.org/article/70871c8fd7b74d20bbcd554b7a7ddeca
Publikováno v:
PLoS Computational Biology, Vol 14, Iss 11, p e1006569 (2018)
How does pattern formation occur accurately when confronted with tissue growth and stochastic fluctuations (noise) in gene expression? Dorso-ventral (D-V) patterning of the mandibular arch specifies upper versus lower jaw skeletal elements through a
Externí odkaz:
https://doaj.org/article/8c593382691a48bc859cf4965438e83e
Autor:
Raphaël Aguillon, Julie Batut, Arul Subramanian, Romain Madelaine, Pascale Dufourcq, Thomas F Schilling, Patrick Blader
Publikováno v:
eLife, Vol 7 (2018)
The zebrafish olfactory epithelium comprises a variety of neuronal populations, which are thought to have distinct embryonic origins. For instance, while ciliated sensory neurons arise from preplacodal ectoderm (PPE), previous lineage tracing studies
Externí odkaz:
https://doaj.org/article/9342fd89a923408f816c8c7ed53c6335
Autor:
Julian Sosnik, Likun Zheng, Christopher V Rackauckas, Michelle Digman, Enrico Gratton, Qing Nie, Thomas F Schilling
Publikováno v:
eLife, Vol 5 (2016)
Morphogen gradients induce sharply defined domains of gene expression in a concentration-dependent manner, yet how cells interpret these signals in the face of spatial and temporal noise remains unclear. Using fluorescence lifetime imaging microscopy
Externí odkaz:
https://doaj.org/article/b6f30c7fb588408684af3aed12061351