Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Stephan Borte"'
Publikováno v:
Diagnostics, Vol 14, Iss 12, p 1286 (2024)
Reduced lymphocyte counts in peripheral blood are one of the most common observations in acute phases of viral infections. Although many studies have already examined the impact of immune (dys)regulation during SARS-CoV-2 infection, there are still u
Externí odkaz:
https://doaj.org/article/9207b017901a45a38b6360f0f8aa4f93
Autor:
Mandy Schwarze, Daniela Volke, Juan Camilo Rojas Echeverri, Robin Schick, Nicole Lakowa, Thomas Grünewald, Johannes Wolf, Stephan Borte, Markus Scholz, Andor Krizsan, Ralf Hoffmann
Publikováno v:
Biology, Vol 13, Iss 4, p 207 (2024)
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) can infect human cells by first attaching to the ACE-2 receptor via its receptor-binding domain (RBD) in the spike protein. Here, we report the influence of N-glycosylation sites of the RBD
Externí odkaz:
https://doaj.org/article/cbcbb68c75094c2a8742d092a84ad010
Autor:
Ji Luo, Alexandra Brakel, Andor Krizsan, Tobias Ludwig, Marina Mötzing, Daniela Volke, Nicole Lakowa, Thomas Grünewald, Claudia Lehmann, Johannes Wolf, Stephan Borte, Sanja Milkovska-Stamenova, Jörg Gabert, Felix Fingas, Markus Scholz, Ralf Hoffmann
Publikováno v:
Virology Journal, Vol 19, Iss 1, Pp 1-10 (2022)
Abstract Background The severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has triggered the worldwide coronavirus disease 2019 (COVID-19) pandemic. Serological assays for the detection of SARS-CoV-2 infections are important to understand t
Externí odkaz:
https://doaj.org/article/c482d7c47e974f4aac666d738e04448e
Autor:
Michael Szardenings, Nicolas Delaroque, Karolin Kern, Lisbeth Ramirez-Caballero, Marcus Puder, Eva Ehrentreich-Förster, Joachim Beige, Sebastian Zürner, Georg Popp, Johannes Wolf, Stephan Borte
Publikováno v:
Vaccines, Vol 11, Iss 9, p 1403 (2023)
(1) Background: Coronavirus proteins are quite conserved amongst endemic strains (eCoV) and SARS-CoV-2. We aimed to evaluate whether peptide epitopes might serve as useful diagnostic biomarkers to stratify previous infections and COVID-19. (2) Method
Externí odkaz:
https://doaj.org/article/73394375d55f43839cbe523e161b032a
Autor:
Lukas Bokelmann, Olaf Nickel, Tomislav Maricic, Svante Pääbo, Matthias Meyer, Stephan Borte, Stephan Riesenberg
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-8 (2021)
Current SARS-CoV-2 diagnostic methods are sensitive yet poorly suited to testing whole communities on a regular basis. Here the authors present Cap-iLAMP that tests gargle lavage samples with an improved colorimetric RT-LAMP.
Externí odkaz:
https://doaj.org/article/232860e3bc4b45058d30368f379f2efe
Autor:
Alexandra Rockstroh, Johannes Wolf, Jasmin Fertey, Sven Kalbitz, Stefanie Schroth, Christoph Lübbert, Sebastian Ulbert, Stephan Borte
Publikováno v:
Emerging Microbes and Infections, Vol 10, Iss 1, Pp 774-781 (2021)
Monitoring the humoral protective immune response and its durability after SARS-CoV-2 infections is essential for risk assessment of reinfections, the improvement of diagnostic methods and the evaluation of vaccine trials. We have analyzed neutralizi
Externí odkaz:
https://doaj.org/article/5b1af8a3e4cd4d7592ea00c2ba6afa5e
Autor:
Mandy Schwarze, Ji Luo, Alexandra Brakel, Andor Krizsan, Nicole Lakowa, Thomas Grünewald, Claudia Lehmann, Johannes Wolf, Stephan Borte, Sanja Milkovska-Stamenova, Jörg Gabert, Markus Scholz, Ralf Hoffmann
Publikováno v:
Pathogens, Vol 11, Iss 12, p 1515 (2022)
This study investigated the IgG and IgA antibody response against recombinant S1 and receptor binding domains (RBD) of the spike (S-) protein and the membrane (M-) protein using a set of 115 serum samples collected from patients infected with SARS-Co
Externí odkaz:
https://doaj.org/article/c5e9b80dd4e84a17bb0ad48e1e8fe4a1
Autor:
Olaf Nickel, Alexandra Rockstroh, Johannes Wolf, Susann Landgraf, Sven Kalbitz, Nils Kellner, Michael Borte, Corinna Pietsch, Jasmin Fertey, Christoph Lübbert, Sebastian Ulbert, Stephan Borte
Publikováno v:
PLoS ONE, Vol 17, Iss 10 (2022)
Background The currently used SARS-CoV-2 mRNA vaccines have proven to induce a strong and protective immune response. However, functional relevance of vaccine-generated antibodies and their temporal progression are still poorly understood. Thus, the
Externí odkaz:
https://doaj.org/article/6638f1b755304fc0911b45cefdc5fb6c
Autor:
Olaf Nickel, Alexandra Rockstroh, Johannes Wolf, Susann Landgraf, Sven Kalbitz, Nils Kellner, Michael Borte, Corinna Pietsch, Jasmin Fertey, Christoph Lübbert, Sebastian Ulbert, Stephan Borte
Publikováno v:
PLoS ONE, Vol 17, Iss 10, p e0263861 (2022)
BackgroundThe currently used SARS-CoV-2 mRNA vaccines have proven to induce a strong and protective immune response. However, functional relevance of vaccine-generated antibodies and their temporal progression are still poorly understood. Thus, the c
Externí odkaz:
https://doaj.org/article/1e479674aaa94ae98f668054c8685e3b
Autor:
Ji Luo, Jennifer Klett, Jörg Gabert, Thomas Lipp, Julia Karbach, Elke Jäger, Stephan Borte, Ralf Hoffmann, Sanja Milkovska-Stamenova
Publikováno v:
Microorganisms, Vol 10, Iss 9, p 1812 (2022)
There is an ongoing need for high-precision serological assays for the quantitation of anti-SARS-CoV-2 antibodies. Here, a trimeric SARS-CoV-2 spike (S) protein was used to develop an ELISA to quantify specific IgG antibodies present in serum, plasma
Externí odkaz:
https://doaj.org/article/6f27e0df4e514497a6d5c40e3e273b07