Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Kuang, Lei"'
Publikováno v:
Frontiers in Molecular Biosciences, Vol 10 (2023)
The Cyclin-dependent kinases (CDKs) play crucial roles in a range of essential cellular processes. While the classical two-step activation mechanism is generally applicable to cell cycle-related CDKs, both CDK7 and CDK8, involved in transcriptional r
Externí odkaz:
https://doaj.org/article/a73e571672d24787a01c89b76b989862
Publikováno v:
Di-san junyi daxue xuebao, Vol 43, Iss 14, Pp 1326-1331 (2021)
Objective To observe the protective effect of mdivi-1, a mitochondrial fission inhibitor, on mice after myocardial ischemia. Methods A total of 140 C57 mice were randomly divided into 4 groups (n=35), that is, Sham group, Sham+mdivi-1 group, ischemia
Externí odkaz:
https://doaj.org/article/7fbcd72c11924dc894096a54616fa620
Publikováno v:
Bioengineering, Vol 10, Iss 4, p 443 (2023)
Peripheral stent could fracture from cyclic loadings as a result of our blood pressures or daily activities. Fatigue performance has therefore become a key issue for peripheral stent design. A simple yet powerful tapered-strut design concept for fati
Externí odkaz:
https://doaj.org/article/082a316573864096b7315bccb302d0f0
Publikováno v:
Di-san junyi daxue xuebao, Vol 42, Iss 4, Pp 326-333 (2020)
Objective To explore the mechanism of activated mitochondrial dynamin-related protein 1 (Drp1) in regulating mitochondrial energy metabolism and aerobic respiration after hypoxia. Methods We observed the changes of Drp1 activity and its relationship
Externí odkaz:
https://doaj.org/article/e6af248a9b7048d1ae648caf37ac1196
Publikováno v:
Di-san junyi daxue xuebao, Vol 42, Iss 1, Pp 50-58 (2020)
Objective To explore the relationship between activated dynamin-related protein 1 (Drp1)-mediated mitochondrial function and energy metabolism after hemorrhagic shock and clarify its potential mechanisms. Methods Sixty C57 female mice (8-weeks old, w
Externí odkaz:
https://doaj.org/article/bc4df6ec497c47b893ca9d033c798a6f
Autor:
Wei Ruan, Xinxin Ma, In Hyuk Bang, Yafen Liang, Jochen Daniel Muehlschlegel, Kuang-Lei Tsai, Tingting W. Mills, Xiaoyi Yuan, Holger K. Eltzschig
Publikováno v:
Biomedicines, Vol 10, Iss 8, p 1939 (2022)
Despite increasing availability and more successful interventional approaches to restore coronary reperfusion, myocardial ischemia-reperfusion injury is a substantial cause of morbidity and mortality worldwide. During myocardial ischemia, the myocard
Externí odkaz:
https://doaj.org/article/b695d39aec5348bea368b64e69c3b71e
Autor:
Edward J Brignole, Kuang-Lei Tsai, Johnathan Chittuluru, Haoran Li, Yimon Aye, Pawel A Penczek, JoAnne Stubbe, Catherine L Drennan, Francisco Asturias
Publikováno v:
eLife, Vol 7 (2018)
Ribonucleotide reductases (RNRs) convert ribonucleotides into deoxyribonucleotides, a reaction essential for DNA replication and repair. Human RNR requires two subunits for activity, the α subunit contains the active site, and the β subunit houses
Externí odkaz:
https://doaj.org/article/5584fcf5814d4af1aea70c4e3427daba