Zobrazeno 1 - 10
of 60
pro vyhledávání: '"Jordan W. Smoller"'
Autor:
Colin G. Walsh, Michael A. Ripperger, Yirui Hu, Yi-han Sheu, Hyunjoon Lee, Drew Wilimitis, Amanda B. Zheutlin, Daniel Rocha, Karmel W. Choi, Victor M. Castro, H. Lester Kirchner, Christopher F. Chabris, Lea K. Davis, Jordan W. Smoller
Publikováno v:
Translational Psychiatry, Vol 14, Iss 1, Pp 1-7 (2024)
Abstract Bipolar disorder is a leading contributor to disability, premature mortality, and suicide. Early identification of risk for bipolar disorder using generalizable predictive models trained on diverse cohorts around the United States could impr
Externí odkaz:
https://doaj.org/article/94f1cfffc2144cf09173606b3f636a0f
Autor:
Giovanni Civieri, MD, Shady Abohashem, MD, Simran S. Grewal, DO, Wesam Aldosoky, MD, Iqra Qamar, MD, Erin Hanlon, BS, Karmel W. Choi, PhD, Lisa M. Shin, PhD, Rachel P. Rosovsky, MD, MPH, Sandeep Chandra Bollepalli, PhD, Hui Chong Lau, Antonis Armoundas, PhD, Antonia V. Seligowski, PhD, Sarah M. Turgeon, PhD, Roger K. Pitman, MD, Francesco Tona, MD, PhD, Jason H. Wasfy, MD, MPhil, Jordan W. Smoller, MD, ScD, Sabino Iliceto, MD, Jill Goldstein, PhD, MPH, Catherine Gebhard, MD, PhD, Michael T. Osborne, MD, Ahmed Tawakol, MD
Publikováno v:
JACC: Advances, Vol 3, Iss 9, Pp 101208- (2024)
Background: Prior studies have incompletely assessed whether the development of cardiometabolic risk factors (CVDRF) (hypertension, hyperlipidemia, and diabetes mellitus) mediates the association between anxiety and depression (anxiety/depression) an
Externí odkaz:
https://doaj.org/article/acba6f594d3d4279a421a77feae50b76
Autor:
Xueyao Wu, Wenqiang Zhang, Xunying Zhao, Li Zhang, Minghan Xu, Yu Hao, Jinyu Xiao, Ben Zhang, Jiayuan Li, Peter Kraft, Jordan W. Smoller, Xia Jiang
Publikováno v:
BMC Medicine, Vol 21, Iss 1, Pp 1-14 (2023)
Abstract Background Both depression and breast cancer (BC) contribute to a substantial global burden of morbidity and mortality among women, and previous studies have observed a potential depression-BC link. We aimed to comprehensively characterize t
Externí odkaz:
https://doaj.org/article/43c629c97a7a4fa2a3f7d79e19c4343d
Publikováno v:
npj Digital Medicine, Vol 6, Iss 1, Pp 1-12 (2023)
Abstract Antidepressant selection is largely a trial-and-error process. We used electronic health record (EHR) data and artificial intelligence (AI) to predict response to four antidepressants classes (SSRI, SNRI, bupropion, and mirtazapine) 4 to 12
Externí odkaz:
https://doaj.org/article/139df4b556e740c181ab8de98d1e4cfa
Autor:
Jakob Seidlitz, Travis T. Mallard, Jacob W. Vogel, Younga H. Lee, Varun Warrier, Gareth Ball, Oskar Hansson, Leanna M. Hernandez, Ayan S. Mandal, Konrad Wagstyl, Michael V. Lombardo, Eric Courchesne, Joseph T. Glessner, Theodore D. Satterthwaite, Richard A.I. Bethlehem, Joshua D. Bernstock, Shinya Tasaki, Bernard Ng, Chris Gaiteri, Jordan W. Smoller, Tian Ge, Raquel E. Gur, Michael J. Gandal, Aaron F. Alexander-Bloch
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113439- (2023)
Summary: Human brain size changes dynamically through early development, peaks in adolescence, and varies up to 2-fold among adults. However, the molecular genetic underpinnings of interindividual variation in brain size remain unknown. Here, we leve
Externí odkaz:
https://doaj.org/article/64ee1401f7fc44968f6a52b884af8318
Autor:
Andrew D. Grotzinger, Travis T. Mallard, Zhaowen Liu, Jakob Seidlitz, Tian Ge, Jordan W. Smoller
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The current study identifies five genomic subclusters of brain regions for cortical thickness and surface area characterized by high levels of shared genetic signal. These subclusters map onto biological and functional parcellations of the cortex.
Externí odkaz:
https://doaj.org/article/558351e4e4a34c35ad3e76b038aa1876
Autor:
Francesca L. Beaudoin, Xinming An, Archana Basu, Yinyao Ji, Mochuan Liu, Ronald C. Kessler, Robert F. Doughtery, Donglin Zeng, Kenneth A. Bollen, Stacey L. House, Jennifer S. Stevens, Thomas C. Neylan, Gari D. Clifford, Tanja Jovanovic, Sarah D. Linnstaedt, Laura T. Germine, Scott L. Rauch, John P. Haran, Alan B. Storrow, Christopher Lewandowski, Paul I. Musey, Phyllis L. Hendry, Sophia Sheikh, Christopher W. Jones, Brittany E. Punches, Michael C. Kurz, Robert A. Swor, Vishnu P. Murty, Meghan E. McGrath, Lauren A. Hudak, Jose L. Pascual, Elizabeth M. Datner, Anna M. Chang, Claire Pearson, David A. Peak, Roland C. Merchant, Robert M. Domeier, Niels K. Rathlev, Brian J. O’ Neil, Paulina Sergot, Leon D. Sanchez, Steven E. Bruce, Justin T. Baker, Jutta Joormann, Mark W. Miller, Robert H. Pietrzak, Deanna M. Barch, Diego A. Pizzagalli, John F. Sheridan, Jordan W. Smoller, Steven E. Harte, James M. Elliott, Karestan C. Koenen, Kerry J. Ressler, Samuel A. McLean
Publikováno v:
Translational Psychiatry, Vol 13, Iss 1, Pp 1-11 (2023)
Abstract The authors sought to characterize adverse posttraumatic neuropsychiatric sequelae (APNS) symptom trajectories across ten symptom domains (pain, depression, sleep, nightmares, avoidance, re-experiencing, anxiety, hyperarousal, somatic, and m
Externí odkaz:
https://doaj.org/article/510c0dddcb9f404fb719cf4b5ffda57e
Autor:
Anna C. F. Lewis, Emma F. Perez, Anya E. R. Prince, Hana R. Flaxman, Lizbeth Gomez, Deanna G. Brockman, Paulette D. Chandler, Benjamin J. Kerman, Matthew S. Lebo, Jordan W. Smoller, Scott T. Weiss, Carrie L. Blout Zawatksy, James B. Meigs, Robert C. Green, Jason L. Vassy, Elizabeth W. Karlson
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Polygenic risk scores (PRS), which offer information about genomic risk for common diseases, have been proposed for clinical implementation. The ways in which PRS information may influence a patient’s health trajectory depend on
Externí odkaz:
https://doaj.org/article/b19f80c5d7664fe791e51eb803730865
Autor:
Tian Ge, Marguerite R. Irvin, Amit Patki, Vinodh Srinivasasainagendra, Yen-Feng Lin, Hemant K. Tiwari, Nicole D. Armstrong, Barbara Benoit, Chia-Yen Chen, Karmel W. Choi, James J. Cimino, Brittney H. Davis, Ozan Dikilitas, Bethany Etheridge, Yen-Chen Anne Feng, Vivian Gainer, Hailiang Huang, Gail P. Jarvik, Christopher Kachulis, Eimear E. Kenny, Atlas Khan, Krzysztof Kiryluk, Leah Kottyan, Iftikhar J. Kullo, Christoph Lange, Niall Lennon, Aaron Leong, Edyta Malolepsza, Ayme D. Miles, Shawn Murphy, Bahram Namjou, Renuka Narayan, Mark J. O’Connor, Jennifer A. Pacheco, Emma Perez, Laura J. Rasmussen-Torvik, Elisabeth A. Rosenthal, Daniel Schaid, Maria Stamou, Miriam S. Udler, Wei-Qi Wei, Scott T. Weiss, Maggie C. Y. Ng, Jordan W. Smoller, Matthew S. Lebo, James B. Meigs, Nita A. Limdi, Elizabeth W. Karlson
Publikováno v:
Genome Medicine, Vol 14, Iss 1, Pp 1-16 (2022)
Abstract Background Type 2 diabetes (T2D) is a worldwide scourge caused by both genetic and environmental risk factors that disproportionately afflicts communities of color. Leveraging existing large-scale genome-wide association studies (GWAS), poly
Externí odkaz:
https://doaj.org/article/e049f828882147afa27dd2a692f0bc18
Autor:
Xinyuan Zhang, Anastasia M. Lucas, Yogasudha Veturi, Theodore G. Drivas, William P. Bone, Anurag Verma, Wendy K. Chung, David Crosslin, Joshua C. Denny, Scott Hebbring, Gail P. Jarvik, Iftikhar Kullo, Eric B. Larson, Laura J. Rasmussen-Torvik, Daniel J. Schaid, Jordan W. Smoller, Ian B. Stanaway, Wei-Qi Wei, Chunhua Weng, Marylyn D. Ritchie
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Circulatory system diseases and nervous system disorders often co-occur in patients. Here the authors use eMERGE and UK BioBank data to identify genomic regions associated with both phenotypes, providing insight into the relationship between these co
Externí odkaz:
https://doaj.org/article/4e82c50b745f4c0f8cbf12c5aaa0ea67