Zobrazeno 1 - 10
of 74
pro vyhledávání: '"Jiri Bartek"'
Autor:
Kang Wang, Ioannis Zerdes, Henrik J. Johansson, Dhifaf Sarhan, Yizhe Sun, Dimitris C. Kanellis, Emmanouil G. Sifakis, Artur Mezheyeuski, Xingrong Liu, Niklas Loman, Ingrid Hedenfalk, Jonas Bergh, Jiri Bartek, Thomas Hatschek, Janne Lehtiö, Alexios Matikas, Theodoros Foukakis
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-24 (2024)
Abstract Although metabolic reprogramming within tumor cells and tumor microenvironment (TME) is well described in breast cancer, little is known about how the interplay of immune state and cancer metabolism evolves during treatment. Here, we charact
Externí odkaz:
https://doaj.org/article/b1fcc99c167b4d128ce9d55c41851b89
Publikováno v:
European Journal of Cell Biology, Vol 103, Iss 2, Pp 151394- (2024)
The nuclear envelope (NE) is a critical component in maintaining the function and structure of the eukaryotic nucleus. The NE and lamina are disassembled during each cell cycle to enable an open mitosis. Nuclear architecture construction and deconstr
Externí odkaz:
https://doaj.org/article/334aa33cb31d446cbf952760a062022c
Autor:
Jochem K. H. Spoor, May den Braber, Clemens M. F. Dirven, Adam Pennycuick, Jirina Bartkova, Jiri Bartek, Vera van Dis, Thierry P. P. van den Bosch, Sieger Leenstra, Subramanian Venkatesan
Publikováno v:
Frontiers in Oncology, Vol 13 (2024)
BackgroundOnly a small group of patients with glioblastoma multiforme (GBM) survives more than 36 months, so-called long-term survivors. Recent studies have shown that chromosomal instability (CIN) plays a prognostic and predictive role among differe
Externí odkaz:
https://doaj.org/article/7782b16b268849169ecbcf4bca2fad8a
Autor:
Fabio Torregrossa, Maria Peris-Celda, Toma Spiriev, Cesare Zoia, Evangelos Drosos, Cristina Aldea, Jiri Bartek, Marlies Bauer, Diogo Belo, Daniela Stastna, Stanislav Kaprovoy, Milan Lepic, Laura Lippa, Malte Mohme, Stefan Motov, Michael Schwake, Felix Stengel, Gerardo Iacopino, Giovanni Grasso, Maria L. Gandìa-Gonzàlez, Torstein R. Meling, Giovanni Raffa
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 102839- (2024)
Externí odkaz:
https://doaj.org/article/5610947f92a84d64898888e94740e443
Autor:
Cesare Zoia, Giorgio Mantovani, Cristina Aldea, Jiri Bartek, Marlies Bauer, Diogo Belo, Evangelos Drosos, Stanislav Kaprovoy, Felix Stengel, Milan Lepic, Laura Lippa, Malte Mohme, Stefan Motov, Michael Schwake, Toma Spiriev, Fabio Torregrossa, Claudius Thomé, Torstein R. Meling, Giovanni Raffa
Publikováno v:
Brain and Spine, Vol 4, Iss , Pp 102734- (2024)
Externí odkaz:
https://doaj.org/article/7ce93a6b253d400297427de06def6ae4
Autor:
Aida Rodríguez López, Maria H. Jørgensen, Jesper F. Havelund, Frederic S. Arendrup, Srinivasa Prasad Kolapalli, Thorbjørn M. Nielsen, Eva Pais, Carsten Jörn Beese, Ahmad Abdul-Al, Anna Constance Vind, Jiri Bartek, Simon Bekker-Jensen, Marta Montes, Panagiotis Galanos, Nils Faergeman, Lotta Happonen, Lisa B. Frankel
Publikováno v:
Cell Reports, Vol 42, Iss 11, Pp 113381- (2023)
Summary: Oncogene-induced senescence (OIS) is a persistent anti-proliferative response that acts as a barrier against malignant transformation. During OIS, cells undergo dynamic remodeling, which involves alterations in protein and organelle homeosta
Externí odkaz:
https://doaj.org/article/194106ee156b484ca5a608d3be2c0d91
Autor:
Tereza Buchtova, Lucie Beresova, Katarina Chroma, Tomas Pluhacek, Tibor Beres, Dominika Kaczorova, Petr Tarkowski, Jiri Bartek, Martin Mistrik
Publikováno v:
Biomedicine & Pharmacotherapy, Vol 163, Iss , Pp 114801- (2023)
Cannabinoids, a class of compounds derived from Cannabis sativa L., have recently become more widely accessible for public consumption in the form of diverse cannabis products, in parallel with weakening the measures that so far restricted their avai
Externí odkaz:
https://doaj.org/article/90a0493e84ad40bab7d6c13603e6fff7
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
RNA has been implicated in DNA repair. This work shows that the interplay of RNAPII-generated nascent RNA, RNA:DNA hybrids and the resection factor CtIP guide DNA double strand break repair pathway choice towards error-free homologous recombination.
Externí odkaz:
https://doaj.org/article/2767a422a100492a835b400bd99be8cf
Autor:
Tereza Buchtova, Zdenek Skrott, Katarina Chroma, Jiri Rehulka, Petr Dzubak, Marian Hajduch, David Lukac, Stefanos Arampatzis, Jiri Bartek, Martin Mistrik
Publikováno v:
Molecular Oncology, Vol 16, Iss 7, Pp 1541-1554 (2022)
Disulfiram (DSF), an established alcohol‐aversion drug, is a candidate for repurposing in cancer treatment. DSF’s antitumor activity is supported by preclinical studies, case reports, and small clinical trials; however, ongoing clinical trials of
Externí odkaz:
https://doaj.org/article/3191b1b97405485c86205c2179ad7bf2
Autor:
Katarina Chroma, Zdenek Skrott, Jan Gursky, Jaroslav Bacovsky, Pavel Moudry, Tereza Buchtova, Martin Mistrik, Jiri Bartek
Publikováno v:
Cell Death and Disease, Vol 13, Iss 3, Pp 1-11 (2022)
Abstract Despite several approved therapeutic modalities, multiple myeloma (MM) remains an incurable blood malignancy and only a small fraction of patients achieves prolonged disease control. The common anti-MM treatment targets proteasome with speci
Externí odkaz:
https://doaj.org/article/3a153f215b3941189abf8b25abc8d0bc