Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Felix Willmund"'
Autor:
Narendra Kumar Chunduri, Paul Menges, Xiaoxiao Zhang, Angela Wieland, Vincent Leon Gotsmann, Balca R. Mardin, Christopher Buccitelli, Jan O. Korbel, Felix Willmund, Maik Kschischo, Markus Raeschle, Zuzana Storchova
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
The mechanisms that allow cancer cells to survive with monosomies are poorly understood. Here the authors analyse p53-deficient monosomic cell lines using transcriptomics and proteomics, and find that impaired ribosome biogenesis and p53 downregulati
Externí odkaz:
https://doaj.org/article/f60023c0c8584a2bac35d7bc8847a8c0
Autor:
Thomas Leisen, Fabian Bietz, Janina Werner, Alex Wegner, Ulrich Schaffrath, David Scheuring, Felix Willmund, Andreas Mosbach, Gabriel Scalliet, Matthias Hahn
Publikováno v:
PLoS Pathogens, Vol 16, Iss 8, p e1008326 (2020)
CRISPR/Cas has become the state-of-the-art technology for genetic manipulation in diverse organisms, enabling targeted genetic changes to be performed with unprecedented efficiency. Here we report on the first establishment of robust CRISPR/Cas editi
Externí odkaz:
https://doaj.org/article/d389d63b33494217a52bf791b2297dce
Publikováno v:
Plants, Vol 9, Iss 2, p 214 (2020)
Cells depend on the continuous renewal of their proteome composition during the cell cycle and in order to replace aberrant proteins or to react to changing environmental conditions. In higher eukaryotes, protein synthesis is achieved by up to five m
Externí odkaz:
https://doaj.org/article/9408ffc5cdf2419394946eae2ef0f163
Autor:
Daniel W. Neef, Alex M. Jaeger, Rocio Gomez-Pastor, Felix Willmund, Judith Frydman, Dennis J. Thiele
Publikováno v:
Cell Reports, Vol 9, Iss 3, Pp 955-966 (2014)
Heat shock transcription factor 1 (HSF1) is an evolutionarily conserved transcription factor that protects cells from protein-misfolding-induced stress and apoptosis. The mechanisms by which cytosolic protein misfolding leads to HSF1 activation have
Externí odkaz:
https://doaj.org/article/52d1219d3ab343a2a033a9ffa76fb02e