Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Christine Dierks"'
Autor:
Lisa Paschold, Donjete Simnica, Ramon Benitez Brito, Tianjiao Zhang, Christoph Schultheiß, Christine Dierks, Mascha Binder
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 3, Pp 1-4 (2022)
Externí odkaz:
https://doaj.org/article/0bcd6e502a164f2db7f3a70acbff3576
Autor:
Vidhya M. Ravi, Nicolas Neidert, Paulina Will, Kevin Joseph, Julian P. Maier, Jan Kückelhaus, Lea Vollmer, Jonathan M. Goeldner, Simon P. Behringer, Florian Scherer, Melanie Boerries, Marie Follo, Tobias Weiss, Daniel Delev, Julius Kernbach, Pamela Franco, Nils Schallner, Christine Dierks, Maria Stella Carro, Ulrich G. Hofmann, Christian Fung, Roman Sankowski, Marco Prinz, Jürgen Beck, Henrike Salié, Bertram Bengsch, Oliver Schnell, Dieter Henrik Heiland
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-16 (2022)
The tumour microenvironment counteracts immune therapy in Glioblastomas. Authors show here, using spatially resolved and single cell transcriptomics, that dysfunctional T cells are induced by a myeloid cell subset via Interleukin-10 signalling, and i
Externí odkaz:
https://doaj.org/article/c8ede93aa6744a97b9b18e93349c871a
Autor:
Juliane Grimm, Donjete Simnica, Nadja Jäkel, Lisa Paschold, Edith Willscher, Susann Schulze, Christine Dierks, Haifa Kathrin Al-Ali, Mascha Binder
Publikováno v:
Blood Cancer Journal, Vol 12, Iss 1, Pp 1-10 (2022)
Abstract Hypomethylating agents (HMA) like azacitidine are licensed for the treatment of acute myeloid leukemia (AML) patients ineligible for allogeneic hematopoietic stem cell transplantation. Biomarker-driven identification of HMA-responsive patien
Externí odkaz:
https://doaj.org/article/1ce8b017093d45eba92be6a584b6ffac
Autor:
Rouven Hoefflin, Adriana Lazarou, Maria Elena Hess, Meike Reiser, Julius Wehrle, Patrick Metzger, Anna Verena Frey, Heiko Becker, Konrad Aumann, Kai Berner, Martin Boeker, Nico Buettner, Christine Dierks, Jesus Duque-Afonso, Michel Eisenblaetter, Thalia Erbes, Ralph Fritsch, Isabell Xiang Ge, Anna-Lena Geißler, Markus Grabbert, Steffen Heeg, Dieter Henrik Heiland, Simone Hettmer, Gian Kayser, Alexander Keller, Anita Kleiber, Alexandra Kutilina, Leman Mehmed, Frank Meiss, Philipp Poxleitner, Justyna Rawluk, Juri Ruf, Henning Schäfer, Florian Scherer, Khalid Shoumariyeh, Andreas Tzschach, Christoph Peters, Tilman Brummer, Martin Werner, Justus Duyster, Silke Lassmann, Cornelius Miething, Melanie Boerries, Anna L. Illert, Nikolas von Bubnoff
Publikováno v:
Cancers, Vol 13, Iss 5, p 1151 (2021)
Molecular precision oncology faces two major challenges: first, to identify relevant and actionable molecular variants in a rapidly changing field and second, to provide access to a broad patient population. Here, we report a four-year experience of
Externí odkaz:
https://doaj.org/article/bc5cb67dc3ba4ca981309ebc3f821777
Autor:
Jonas S. Jutzi, Maria Kleppe, Jennifer Dias, Hans Felix Staehle, Kaitlyn Shank, Julie Teruya-Feldstein, Sudheer Madan Mohan Gambheer, Christine Dierks, Hugh Y. Rienhoff, Jr, Ross L. Levine, Heike L. Pahl
Publikováno v:
HemaSphere, Vol 2, Iss 3 (2018)
Abstract. Despite recent advances, the myeloproliferative neoplasms (MPNs) are attended by considerable morbidity and mortality. Janus kinase (Jak) inhibitors such as ruxolitinib manage symptoms but do not substantially change the natural history of
Externí odkaz:
https://doaj.org/article/9a5226cfef28450b8b2347a82de72292
Autor:
Carl Philipp Simon-Gabriel, Katharina Foerster, Shifa Saleem, Dorothee Bleckmann, Marco Benkisser-Petersen, Nicolas Thornton, Kazuo Umezawa, Sarah Decker, Meike Burger, Hendrik Veelken, Rainer Claus, Christine Dierks, Justus Duyster, Katja Zirlik
Publikováno v:
Haematologica, Vol 103, Iss 1 (2018)
Nuclear factor κ-light-chain-enhancer of activated B cells (NF-κB) is known to play an important role in the pathogenesis of chronic lymphocytic leukemia (CLL). Several NF-κB inhibitors were shown to successfully induce apoptosis of CLL cells in v
Externí odkaz:
https://doaj.org/article/d3a6b3c8c8694431b1abe63709586edd
Autor:
Marco Benkisser-Petersen, Maike Buchner, Arlette Dörffel, Marcus Dühren-von-Minden, Rainer Claus, Kathrin Kläsener, Kerstin Leberecht, Meike Burger, Christine Dierks, Hassan Jumaa, Fabio Malavasi, Michael Reth, Hendrik Veelken, Justus Duyster, Katja Zirlik
Publikováno v:
PLoS ONE, Vol 11, Iss 12, p e0169159 (2016)
The survival and proliferation of CLL cells depends on microenvironmental contacts in lymphoid organs. CD38 is a cell surface receptor that plays an important role in survival and proliferation signaling in CLL. In this study we demonstrate SYK's dir
Externí odkaz:
https://doaj.org/article/62e623d9e389493dba53993b6041906a