Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Buxbaum, Joseph D."'
Autor:
Buxbaum Joseph D, Betancur Catalina, Bozdagi Ozlem, Dorr Nate P, Elder Gregory A, Hof Patrick R
Publikováno v:
Molecular Autism, Vol 3, Iss 1, p 1 (2012)
Abstract Background There is interest in defining mouse neurobiological phenotypes useful for studying autism spectrum disorders (ASD) in both forward and reverse genetic approaches. A recurrent focus has been on high-order behavioral analyses, inclu
Externí odkaz:
https://doaj.org/article/2b2612058d6e4fcc8cdf3d0a39aa27fe
Autor:
Hof Patrick R, Andreasson Katrin I, Woodling Nathaniel S, Schoen Michael, Arons Magali, Udvardi Patrick T, Schmeisser Michael J, Grabrucker Andreas M, Buxbaum Joseph D, Garner Craig C, Boeckers Tobias M
Publikováno v:
Molecular Neurodegeneration, Vol 6, Iss 1, p 65 (2011)
Abstract Background Memory deficits in Alzheimer's disease (AD) manifest together with the loss of synapses caused by the disruption of the postsynaptic density (PSD), a network of scaffold proteins located in dendritic spines. However, the underlyin
Externí odkaz:
https://doaj.org/article/f57354da392545f19d6dae3335304762
Autor:
Bozdagi Ozlem, Sakurai Takeshi, Papapetrou Danae, Wang Xiaobin, Dickstein Dara L, Takahashi Nagahide, Kajiwara Yuji, Yang Mu, Katz Adam M, Scattoni Maria, Harris Mark J, Saxena Roheeni, Silverman Jill L, Crawley Jacqueline N, Zhou Qiang, Hof Patrick R, Buxbaum Joseph D
Publikováno v:
Molecular Autism, Vol 1, Iss 1, p 15 (2010)
Abstract Background SHANK3 is a protein in the core of the postsynaptic density (PSD) and has a critical role in recruiting many key functional elements to the PSD and to the synapse, including components of α-amino-3-hydroxyl-5-methyl-4-isoxazole-p
Externí odkaz:
https://doaj.org/article/6d808fe70278469f920a71a447d6ced6
Publikováno v:
Molecular Autism, Vol 1, Iss 1, p 6 (2010)
Abstract Many psychiatric conditions and traits are associated with significant heritability. Genetic risk for psychiatric conditions encompass rare variants, identified due to major effect, as well as common variants, the latter analyzed by associat
Externí odkaz:
https://doaj.org/article/10a75315c8e749c9a8e6df5725bc59b0
Autor:
McInnes L, Nakamine Alisa, Pilorge Marion, Brandt Tracy, Jiménez González Patricia, Fallas Marietha, Manghi Elina R, Edelmann Lisa, Glessner Joseph, Hakonarson Hakon, Betancur Catalina, Buxbaum Joseph D
Publikováno v:
Molecular Autism, Vol 1, Iss 1, p 5 (2010)
Abstract Background The 15q24 microdeletion syndrome has been recently described as a recurrent, submicroscopic genomic imbalance found in individuals with intellectual disability, typical facial appearance, hypotonia, and digital and genital abnorma
Externí odkaz:
https://doaj.org/article/ff6943ec5f924d748a379d504b2e35a5
Autor:
Buxbaum Joseph D, Baron-Cohen Simon
Publikováno v:
Molecular Autism, Vol 1, Iss 1, p 1 (2010)
Externí odkaz:
https://doaj.org/article/89531146a910407f81cd7caa1c68e4cb
Autor:
Taddei Kevin, Schmeidler James, Krug Lisa, Takahashi Nagahide, Franciosi Sonia, Kajiwara Yuji, Haroutunian Vahram, Fried Ulrik, Ehrlich Michelle, Martins Ralph N, Gandy Samuel, Buxbaum Joseph D
Publikováno v:
Molecular Neurodegeneration, Vol 5, Iss 1, p 1 (2010)
Abstract Background The low-density lipoprotein receptor related protein 1 (LRP1) has been implicated in Alzheimer's disease (AD) but its signalling has not been fully evaluated. There is good evidence that the cytoplasmic domain of LRP1 is involved
Externí odkaz:
https://doaj.org/article/28607fc34f234fa4a8e1c740980856f1
Autor:
Buxbaum Joseph D, Martins Ralph N, Hyslop Peter, Westaway David, Fraser Paul, Ho Lap, Schmeidler James, Brautigam Hannah, Thomas Carlos, Pedrini Steve, Pasinetti Giulio M, Dickstein Dara L, Hof Patrick R, Ehrlich Michelle E, Gandy Sam
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 40 (2009)
Abstract Objective Alzheimer's disease (AD) is a progressive neurodegenerative disease of the central nervous system (CNS). Recently, an increased interest in the role diet plays in the pathology of AD has resulted in a focus on the detrimental effec
Externí odkaz:
https://doaj.org/article/7dde908482fa4ecab9bc645eac7c929f
Autor:
De Gasperi Rita, Janssen William GM, Oung Twethida, Oler Elizabeth, English Daniel F, Gama Sosa Miguel A, Franciosi Sonia, Schmeidler James, Dickstein Dara L, Schmitz Christoph, Gandy Sam, Hof Patrick R, Buxbaum Joseph D, Elder Gregory A
Publikováno v:
Molecular Neurodegeneration, Vol 4, Iss 1, p 42 (2009)
Abstract Background Hypercholesterolemia causes atherosclerosis in medium to large sized arteries. Cholesterol is less known for affecting the microvasculature and has not been previously reported to induce microvascular pathology in the central nerv
Externí odkaz:
https://doaj.org/article/8d4b92a42e744af4896757214bf2bd45
Autor:
Reichert Jennifer G, Nakamine Alisa, Cohen Ninette, Goldsmith Juliet E, Edelmann Lisa, Cai Guiqing, Hoffman Ellen J, Zurawiecki Danielle M, Silverman Jeremy M, Hollander Eric, Soorya Latha, Anagnostou Evdokia, Betancur Catalina, Buxbaum Joseph D
Publikováno v:
BMC Medical Genomics, Vol 1, Iss 1, p 50 (2008)
Abstract Background It has previously been shown that specific microdeletions and microduplications, many of which also associated with cognitive impairment (CI), can present with autism spectrum disorders (ASDs). Multiplex ligation-dependent probe a
Externí odkaz:
https://doaj.org/article/98372edc90754983aca3a630b2a5e242