Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Bernd Kaspers"'
Autor:
Simon Ullrich, Susanne Leidescher, Yana Feodorova, Katharina Thanisch, Jean-Baptiste Fini, Bernd Kaspers, Frank Weber, Boyka Markova, Dagmar Führer, Mirian Romitti, Stefan Krebs, Helmut Blum, Heinrich Leonhardt, Sabine Costagliola, Heike Heuer, Irina Solovei
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Abnormalities are indispensable for studying normal biological processes and mechanisms. In the present work, we draw attention to the remarkable phenomenon of a perpetually and robustly upregulated gene, the thyroglobulin gene (Tg). The gene is expr
Externí odkaz:
https://doaj.org/article/90f08466957648079f8c4cfd025f892b
Autor:
Stefan Dascalu, Stephen G. Preston, Robert J. Dixon, Patrik G. Flammer, Steven Fiddaman, Amy Boyd, Joshua E. Sealy, Jean-Remy Sadeyen, Bernd Kaspers, Philippe Velge, Munir Iqbal, Michael B. Bonsall, Adrian L. Smith
Publikováno v:
Frontiers in Immunology, Vol 13 (2023)
Microbial colonisation is paramount to the normal development of the immune system, particularly at mucosal sites. However, the relationships between the microbiome and the adaptive immune repertoire have mostly been explored in rodents and humans. H
Externí odkaz:
https://doaj.org/article/539a59f37cd34755b0cdafb0d2764705
Autor:
Robert Dixon, Stephen G. Preston, Stefan Dascalu, Patrik G. Flammer, Steven R. Fiddaman, Kirstie McLoughlin, Amy Boyd, Jiri Volf, Ivan Rychlik, Michael B. Bonsall, Bernd Kaspers, Adrian L. Smith
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-19 (2021)
Abstract Background Despite increasing interest in γδ T cells and their non-classical behaviour, most studies focus on animals with low numbers of circulating γδ T cells, such as mice and humans. Arguably, γδ T cell functions might be more prom
Externí odkaz:
https://doaj.org/article/f713c3f9b12d4476977e534d0be2cb9d
Autor:
Robert Dixon, Stephen G. Preston, Stefan Dascalu, Patrik G. Flammer, Steven R. Fiddaman, Kirstie McLoughlin, Amy Boyd, Jiri Volf, Ivan Rychlik, Michael B. Bonsall, Bernd Kaspers, Adrian L. Smith
Publikováno v:
BMC Genomics, Vol 22, Iss 1, Pp 1-3 (2021)
Externí odkaz:
https://doaj.org/article/1f47b623ecea4bf8829ff2ecdbac030f
Early-Life Immune System Maturation in Chickens Using a Synthetic Community of Cultured Gut Bacteria
Autor:
Christian Zenner, Thomas C. A. Hitch, Thomas Riedel, Esther Wortmann, Stefan Tiede, Eva M. Buhl, Birte Abt, Klaus Neuhaus, Philippe Velge, Jörg Overmann, Bernd Kaspers, Thomas Clavel
Publikováno v:
mSystems, Vol 6, Iss 3 (2021)
The immune system plays a crucial role in sustaining animal health. Its development is markedly influenced by early microbial colonization of the gastrointestinal tract.
Externí odkaz:
https://doaj.org/article/77ed836b5fd5428dbef2f6c23eb63a8e
Autor:
Samer Halabi, Michael Ghosh, Stefan Stevanović, Hans-Georg Rammensee, Luca D Bertzbach, Benedikt B Kaufer, Martin C Moncrieffe, Bernd Kaspers, Sonja Härtle, Jim Kaufman
Publikováno v:
PLoS Biology, Vol 19, Iss 4, p e3001057 (2021)
Viral diseases pose major threats to humans and other animals, including the billions of chickens that are an important food source as well as a public health concern due to zoonotic pathogens. Unlike humans and other typical mammals, the major histo
Externí odkaz:
https://doaj.org/article/79281ce651de4820a7c603acf1837adc
Autor:
Nandor Nagy, Florian Busalt, Viktoria Halasy, Marina Kohn, Stefan Schmieder, Nora Fejszak, Bernd Kaspers, Sonja Härtle
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
In contrast to mammals, early B cell differentiation and diversification of the antibody repertoire in chickens do not take place in the bone marrow but in a specialized gut associated lymphoid tissue (GALT), the bursa of Fabricius. During embryonic
Externí odkaz:
https://doaj.org/article/3fa28cfd63bf4ec0a25f41429ff61372
Autor:
Li Li, Colin Pielsticker, Zifeng Han, Tereza Kubasová, Ivan Rychlik, Bernd Kaspers, Silke Rautenschlein
Publikováno v:
Gut Pathogens, Vol 10, Iss 1, Pp 1-14 (2018)
Abstract Background Campylobacter jejuni is considered as a chicken commensal. The gut microbiota and the immune status of the host may affect its colonization. Infectious bursal disease virus (IBDV) is an immunosuppressive virus of chickens, which a
Externí odkaz:
https://doaj.org/article/5991f4613c81431485a50b83f0cd5a83
Autor:
Jiri Volf, Ondrej Polansky, Zuzana Sekelova, Philippe Velge, Catherine Schouler, Bernd Kaspers, Ivan Rychlik
Publikováno v:
Veterinary Research, Vol 48, Iss 1, Pp 1-10 (2017)
Abstract Gut microbiota is of considerable importance for each host. Despite this, germ-free animals can be obtained and raised to sexual maturity and consequences of the presence or absence of gut microbiota on gene expression of the host remain unc
Externí odkaz:
https://doaj.org/article/38035914f73b4cf79b7b368a6a8d1fe4
Publikováno v:
BMC Genomics, Vol 18, Iss 1, Pp 1-21 (2017)
Abstract Background Type I interferons are major players against viral infections and mediate their function by the induction of Interferon regulated genes (IRGs). Recently, it became obvious that these cytokines have a multitude of additional functi
Externí odkaz:
https://doaj.org/article/94be0e7c8a144048916ffc7f7bf6603a