Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Angela M. Crook"'
Autor:
Conor D. Tweed, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Lerato Mohapi, Michael E. Murphy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Stephen H. Gillespie
Publikováno v:
BMC Pulmonary Medicine, Vol 19, Iss 1, Pp 1-9 (2019)
Abstract Background The phase III REMoxTB study prospectively enrolled HIV-positive (with CD4+ count > 250 cells, not on anti-retroviral therapy) and HIV-negative patients. We investigated the incidence of adverse events and cure rates according to H
Externí odkaz:
https://doaj.org/article/d4f6503cd6b943dbb18e73105c9b0eb8
Autor:
James A. Seddon, Anthony J. Garcia-Prats, Susan E. Purchase, Muhammad Osman, Anne-Marie Demers, Graeme Hoddinott, Angela M. Crook, Ellen Owen-Powell, Margaret J. Thomason, Anna Turkova, Diana M. Gibb, Lee Fairlie, Neil Martinson, H. Simon Schaaf, Anneke C. Hesseling
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-11 (2018)
Abstract Background Multidrug-resistant (MDR) tuberculosis (TB) presents a challenge for global TB control. Treating individuals with MDR-TB infection to prevent progression to disease could be an effective public health strategy. Young children are
Externí odkaz:
https://doaj.org/article/a134014bc6634d18a556e22c01eb8f43
Autor:
Nurulamin M. Noor, Sarah L. Pett, Hanif Esmail, Angela M. Crook, Claire L. Vale, Matthew R. Sydes, Mahesh K.B. Parmar
Publikováno v:
F1000Research, Vol 9 (2020)
Global health pandemics, such as coronavirus disease 2019 (COVID-19), require efficient and well-conducted trials to determine effective interventions, such as treatments and vaccinations. Early work focused on rapid sequencing of severe acute respir
Externí odkaz:
https://doaj.org/article/61d8b86fa4a24a4f819a91086761b336
Autor:
Nurulamin M. Noor, Sarah L. Pett, Hanif Esmail, Angela M. Crook, Claire L. Vale, Matthew R. Sydes, Mahesh K.B. Parmar
Publikováno v:
F1000Research, Vol 9 (2020)
Global health pandemics, such as coronavirus disease 2019 (COVID-19), require efficient and well-conducted trials to determine effective interventions, such as treatments and vaccinations. Early work focused on rapid sequencing of severe acute respir
Externí odkaz:
https://doaj.org/article/22a7038099c64646b63619103441991d
Autor:
Conor D. Tweed, Angela M. Crook, Evans I. Amukoye, Rodney Dawson, Andreas H. Diacon, Madeline Hanekom, Timothy D. McHugh, Carl M. Mendel, Sarah K. Meredith, Michael E. Murphy, Saraswathi E. Murthy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha P. Singh, Melvin Spigelman, Genevieve H. Wills, Stephen H. Gillespie
Publikováno v:
BMC Infectious Diseases, Vol 18, Iss 1, Pp 1-11 (2018)
Abstract Background The incidence and severity of tuberculosis chemotherapy toxicity is poorly characterised. We used data available from patients in the REMoxTB trial to provide an assessment of the risks associated with the standard regimen and two
Externí odkaz:
https://doaj.org/article/87ffe9cc14bf494197dd9d05a700110f
Autor:
Chishala Chabala, Anna Turkova, Margaret J. Thomason, Eric Wobudeya, Syed Hissar, Vidya Mave, Marieke van der Zalm, Megan Palmer, Monica Kapasa, Perumal K. Bhavani, Sarath Balaji, Priyanka A. Raichur, Anne-Marie Demers, Graeme Hoddinott, Ellen Owen-Powell, Aarti Kinikar, Philippa Musoke, Veronica Mulenga, Rob Aarnoutse, Helen McIlleron, Anneke Hesseling, Angela M. Crook, Mark Cotton, Diana M. Gibb, on behalf of the SHINE trial team
Publikováno v:
Trials, Vol 19, Iss 1, Pp 1-12 (2018)
Abstract Background Tuberculosis (TB) in children is frequently paucibacillary and non-severe forms of pulmonary TB are common. Evidence for tuberculosis treatment in children is largely extrapolated from adult studies. Trials in adults with smear-ne
Externí odkaz:
https://doaj.org/article/c7b492728303475aa269ac5a2bc5f4ce
Autor:
Conor Duncan Tweed, Genevieve Helen Wills, Angela M. Crook, Rodney Dawson, Andreas H. Diacon, Cheryl E. Louw, Timothy D. McHugh, Carl Mendel, Sarah Meredith, Lerato Mohapi, Michael E. Murphy, Stephen Murray, Sara Murthy, Andrew J. Nunn, Patrick P. J. Phillips, Kasha Singh, M. Spigelman, S. H. Gillespie
Publikováno v:
BMC Medicine, Vol 16, Iss 1, Pp 1-10 (2018)
Abstract Background Drug-induced liver injury (DILI) is a common complication of tuberculosis treatment. We utilised data from the REMoxTB clinical trial to describe the incidence of predisposing factors and the natural history in patients with liver
Externí odkaz:
https://doaj.org/article/9c5b8d40012f497db02bc3f9607be6f2
Autor:
Patrick P. J. Phillips, Carl M. Mendel, Andrew J. Nunn, Timothy D. McHugh, Angela M. Crook, Robert Hunt, Anna Bateson, Stephen H. Gillespie
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-9 (2017)
Abstract Background Tuberculosis kills more people than any other infectious disease, and new regimens are essential. The primary endpoint for confirmatory phase III trials for new regimens is a composite outcome that includes bacteriological treatme
Externí odkaz:
https://doaj.org/article/41b6224a176d4f7e8c044ded9a5e8eb4
Autor:
Michael E. Murphy, Patrick P. J. Phillips, Carl M. Mendel, Emily Bongard, Anna L. C. Bateson, Robert Hunt, Saraswathi Murthy, Kasha P. Singh, Michael Brown, Angela M. Crook, Andrew J. Nunn, Sarah K. Meredith, Marc Lipman, Timothy D. McHugh, Stephen H. Gillespie, On behalf of the REMoxTB Consortium
Publikováno v:
BMC Medicine, Vol 15, Iss 1, Pp 1-10 (2017)
Abstract Background The use of early morning sputum samples (EMS) to diagnose tuberculosis (TB) can result in treatment delay given the need for the patient to return to the clinic with the EMS, increasing the chance of patients being lost during the
Externí odkaz:
https://doaj.org/article/6ed07cb9f278456d91f517953c95470c
Autor:
Charles S Morrison, Pai-Lien Chen, Cynthia Kwok, Jared M Baeten, Joelle Brown, Angela M Crook, Lut Van Damme, Sinead Delany-Moretlwe, Suzanna C Francis, Barbara A Friedland, Richard J Hayes, Renee Heffron, Saidi Kapiga, Quarraisha Abdool Karim, Stephanie Karpoff, Rupert Kaul, R Scott McClelland, Sheena McCormack, Nuala McGrath, Landon Myer, Helen Rees, Ariane van der Straten, Deborah Watson-Jones, Janneke H H M van de Wijgert, Randy Stalter, Nicola Low
Publikováno v:
PLoS Medicine, Vol 12, Iss 1, p e1001778 (2015)
BackgroundObservational studies of a putative association between hormonal contraception (HC) and HIV acquisition have produced conflicting results. We conducted an individual participant data (IPD) meta-analysis of studies from sub-Saharan Africa to
Externí odkaz:
https://doaj.org/article/c1b0c8811a234180b6770381629ca374