Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Preclinical research"'
Autor:
Hanwei Yue, Lin Bai
Publikováno v:
Animal Models and Experimental Medicine, Vol 7, Iss 1, Pp 3-11 (2024)
Abstract In recent years, humanized immune system (HIS) mice have been gradually used as models for preclinical research in pharmacotherapies and cell therapies with major breakthroughs in tumor and other fields, better mimicking the human immune sys
Externí odkaz:
https://doaj.org/article/10057c4c05974220b25d87db6ac0b08c
Autor:
Manoj M. Lalu, Dawn Richards, Madison Foster, Brittany French, Angela M. Crawley, Kirsten M. Fiest, Kathryn Hendrick, Kimberly F. Macala, Asher A. Mendelson, Pat Messner, Stuart G. Nicholls, Justin Presseau, Cheryle A. Séguin, Patrick Sullivan, Bernard Thébaud, Dean A. Fergusson
Publikováno v:
Research Involvement and Engagement, Vol 10, Iss 1, Pp 1-9 (2024)
Abstract Background Patient engagement in research is the meaningful and collaborative interaction between patients and researchers throughout the research process. Patient engagement can help to ensure patient-oriented values and perspectives are in
Externí odkaz:
https://doaj.org/article/d1346b77fe94404e9245270fe80b7977
Autor:
Alexandra Bannach-Brown, Torsten Rackoll, Nurcennet Kaynak, Natascha Drude, René Aquarius, Sofija Vojvodić, Mariana Abreu, Julia M. L. Menon, Kimberley E. Wever
Publikováno v:
BMC Medical Research Methodology, Vol 24, Iss 1, Pp 1-8 (2024)
Abstract Systematic reviews are an essential tool in identifying knowledge gaps and synthesizing evidence from in vivo animal research to improve human health. The review process follows an explicit and systematic methodology to minimize bias, but is
Externí odkaz:
https://doaj.org/article/f3a29a5051a84b2b924dbd2ba561f5f6
Autor:
Robyn A. Smith, Judith Slocombe, Jo Cockwill, Kathy Minas, George Kiossoglou, Katya Gray, William Lawrence, Michelle Iddles, Clare Scott, Lorraine A. O'Reilly
Publikováno v:
Health Expectations, Vol 27, Iss 1, Pp n/a-n/a (2024)
Abstract Background and Context Involving people with lived experience of health conditions and the public (consumers) in health research is supported by policy, practice and research funding schemes. However, consumer involvement programmes in disco
Externí odkaz:
https://doaj.org/article/26a76aa606a241b79cb1d02d23688889
Autor:
Pádraig Carroll, Éimear Smith, Adrian Dervan, Ciarán McCarthy, Cliff Beirne, John Quinlan, Geoff Harte, Dónal O'Flynn, Fergal J. O'Brien, Frank Moriarty, Michelle Flood
Publikováno v:
Health Expectations, Vol 27, Iss 1, Pp n/a-n/a (2024)
Abstract Introduction Patient and public involvement (PPI) in research is an embedded practice in clinical research, however, its role in preclinical or laboratory‐based research is less well established and presents specific challenges. This study
Externí odkaz:
https://doaj.org/article/cd673c58f26a4e558fa85bf16c39f3d2
Autor:
Emmanuelle Totain, Loïc Lindner, Nicolas Martin, Yolande Misseri, Alexandra Iché, Marie-Christine Birling, Tania Sorg, Yann Herault, Alain Bousquet-Melou, Pascale Bouillé, Christine Duthoit, Guillaume Pavlovic, Severine Boullier
Publikováno v:
Laboratory Animal Research, Vol 39, Iss 1, Pp 1-15 (2023)
Abstract Background Animal models are essential to understand the physiopathology of human diseases but also to evaluate new therapies. However, for several diseases there is no appropriate animal model, which complicates the development of effective
Externí odkaz:
https://doaj.org/article/d942d7339ede45d5b5ac1aac24e653db
Autor:
Jenessa N. Johnston, Lisa Ridgway, Sarah Cary-Barnard, Josh Allen, Carla L. Sanchez-Lafuente, Brady Reive, Lisa E. Kalynchuk, Hector J. Caruncho
Publikováno v:
Research Involvement and Engagement, Vol 7, Iss 1, Pp 1-11 (2021)
Plain English summary This paper presents a roadmap for patient-oriented research in mental health in Canada. At the level of laboratory science, the direct involvement of patients and their collaboration with researchers on experimental development
Externí odkaz:
https://doaj.org/article/24a1bd684a314223b91ccdd274734ab4
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 9, Iss 4, Pp 248-255 (2019)
The quality and effectiveness of preclinical trials of medicines depend on compliance with the Good Laboratory Practice (GLP) principles. At the same time, the data of the World Health Organisation (WHO) and the analysis of the regulatory framework s
Externí odkaz:
https://doaj.org/article/9a8f5a13a8194e63bb3e28a35443d4bf
Publikováno v:
Ведомости Научного центра экспертизы средств медицинского применения, Vol 7, Iss 1, Pp 25-32 (2018)
The article discusses various aspects of risk management for quality assurance (QA) of preclinical studies of drugs. The authors analysed risk management methods and approaches, and defined relevant risk management methods to be used in preclinical s
Externí odkaz:
https://doaj.org/article/30b584c708ad49d48bcd80af80d0080a