Zobrazeno 1 - 10
of 53
pro vyhledávání: '"Turnbull, P."'
Autor:
Elizabeth Min, Natalie T. Boelman, Laura Gough, Jennie R. McLaren, Edward B. Rastetter, Rebecca J. Rowe, Adrian Rocha, Matthew H. Turnbull, Kevin L. Griffin
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-7 (2024)
Abstract A significant warming effect on arctic tundra is greening. Although this increase in predominantly woody vegetation has been linked to increases in gross primary productivity, increasing temperatures also stimulate ecosystem respiration. We
Externí odkaz:
https://doaj.org/article/7097e8acc2fa47f1acd8c1ce5d71e077
Publikováno v:
Communications Biology, Vol 7, Iss 1, Pp 1-13 (2024)
Abstract Antibodies with lambda light chains (λ-antibodies) are generally considered to be less developable than those with kappa light chains (κ-antibodies). Though this hypothesis has not been formally established, it has led to substantial syste
Externí odkaz:
https://doaj.org/article/3aa009e08b094dc2937b78da4414d5a3
Autor:
Elizaveta A. Olkhova, Carla Bradshaw, Alasdair Blain, Debora Alvim, Doug M. Turnbull, Fiona E. N. LeBeau, Yi Shiau Ng, Gráinne S. Gorman, Nichola Z. Lax
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-17 (2023)
Abstract Mitochondrial diseases comprise a common group of neurometabolic disorders resulting from OXPHOS defects, that may manifest with neurological impairments, for which there are currently no disease-modifying therapies. Previous studies suggest
Externí odkaz:
https://doaj.org/article/d905e99197394a9cbdda0d8fb7b9226c
Autor:
Valentina Balducci, Francesco Scardigli, Magdalena Harakalova, J. Peter. van Tintelen, Pieter A. Doevendans, Kevin D. Costa, Irene C. Turnbull, Joost P. G. Sluijter, Francesca Stillitano
Publikováno v:
Stem Cell Research, Vol 72, Iss , Pp 103208- (2023)
The rare genetic alteration PLN-c.(40_42delAGA), leading to the deletion of arginine 14 (p.R14del) in phospholamban, is associated with dilated and arrhythmogenic cardiomyopathies occurring in early-adulthood. However, some carriers remain asymptomat
Externí odkaz:
https://doaj.org/article/388758bbc8f347e6ba63047bd7670b59
Publikováno v:
BMC Biology, Vol 20, Iss 1, Pp 1-16 (2022)
Abstract Background Despite a global prevalence of photosynthetic organisms in the ocean’s mesophotic zone (30–200+ m depth), the mechanisms that enable photosynthesis to proceed in this low light environment are poorly defined. Red coralline alg
Externí odkaz:
https://doaj.org/article/398a75cc9a3e4a23b16ee2690175dbc0
Autor:
Graham Turnbull, Sutejas Chari, Zehao Li, Ziyue Yang, Catharina Maria Alam, Christofer J. Clemente, Parvez Alam
Publikováno v:
Biology Open, Vol 12, Iss 5 (2023)
Externí odkaz:
https://doaj.org/article/def23265fdad4d49afa7c6670d6cdb53
Autor:
Peng Zhang, Yu Liu, Chunfeng Li, Lindsay D. Stine, Pei-Hui Wang, Matthew W. Turnbull, Haodi Wu, Qing Liu
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 11 (2023)
Coronavirus disease 2019 (COVID-19) is associated with adverse impacts in the cardiovascular system, but the mechanisms driving this response remain unclear. In this study, we conducted “pseudoviral infection” of SARS-CoV-2 subunits to evaluate t
Externí odkaz:
https://doaj.org/article/89e54995220b4e68a072a3b26216443d
Autor:
Anna L. Gray, Richard Karlsson, Abigail R.E. Roberts, Amanda J.L. Ridley, Nabina Pun, Bakhtbilland Khan, Craig Lawless, Rafael Luís, Martyna Szpakowska, Andy Chevigné, Catherine E. Hughes, Laura Medina-Ruiz, Holly L. Birchenough, Iashia Z. Mulholland, Catherina L. Salanga, Edwin A. Yates, Jeremy E. Turnbull, Tracy M. Handel, Gerard J. Graham, Thomas A. Jowitt, Ingo Schiessl, Ralf P. Richter, Rebecca L. Miller, Douglas P. Dyer
Publikováno v:
Cell Reports, Vol 42, Iss 1, Pp 111930- (2023)
Summary: Leukocyte recruitment from the vasculature into tissues is a crucial component of the immune system but is also key to inflammatory disease. Chemokines are central to this process but have yet to be therapeutically targeted during inflammati
Externí odkaz:
https://doaj.org/article/a86b22d342b64eea907a81850c7c8b16
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 17, p 13416 (2023)
Induced pluripotent stem cell-derived cardiomyocytes (iPSC-CMs) hold enormous potential in cardiac disease modeling, drug screening, and regenerative medicine. Furthermore, patient-specific iPSC-CMS can be tested for personalized medicine. To provide
Externí odkaz:
https://doaj.org/article/6798e149be1b4204a1fccb15d54a287f
Autor:
Susan L. Lindsay, Rebecca Sherrard Smith, Edwin A. Yates, Colin Cartwright, Bryan E. Thacker, Jeremy E. Turnbull, Charles A. Glass, Susan C. Barnett
Publikováno v:
Biology, Vol 12, Iss 3, p 407 (2023)
Therapies that target the multicellular pathology of central nervous system (CNS) disease/injury are urgently required. Modified non-anticoagulant heparins mimic the heparan sulphate (HS) glycan family and have been proposed as therapeutics for CNS r
Externí odkaz:
https://doaj.org/article/1e07cdcdee96451c90a68e210f467151