Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Hong Chen"'
Autor:
Siyu Xia, Ming Wu, Xinhao Zhou, Xiu Zhang, Lina Ye, Kang Zhang, Yiyi Kang, Jun Liu, Yunci Zhang, Wang Wu, Dirong Dong, Hong Chen, Hui Li
Publikováno v:
Stem Cell Research & Therapy, Vol 13, Iss 1, Pp 1-15 (2022)
Abstract Background There is unmet need for effective therapies of intrauterine adhesions (IUAs) that are common cause of menstrual disturbance and infertility, since current clinical procedures do not improve prognosis for patients with moderate to
Externí odkaz:
https://doaj.org/article/68702bcd52bf49d5a477b17d5d3b3d72
Autor:
Pengcheng Xiao, Zhenglin Zhu, Chengcheng Du, Yongsheng Zeng, Junyi Liao, Qiang Cheng, Hong Chen, Chen Zhao, Wei Huang
Publikováno v:
Stem Cell Research & Therapy, Vol 12, Iss 1, Pp 1-16 (2021)
Abstract Background Bone morphogenetic protein 2 (BMP2) is a promising chondrogenic growth factor for cartilage tissue-engineering, but it also induces robust endochondral ossification. Human synovial-derived mesenchymal stromal cells (hSMSCs) have a
Externí odkaz:
https://doaj.org/article/84cd4192810c4ae1bcfe77d387e67770
Publikováno v:
Journal of Lipid Research, Vol 60, Iss 1, Pp 121-134 (2019)
In this study, a novel strategy based on acetone stable-isotope derivatization coupled with HPLC-MS for profiling and accurate quantification of aminophospholipids (phosphatidylethanolamine and phosphatidylserine) in biological samples was developed.
Externí odkaz:
https://doaj.org/article/b147c7ae69694ab89a8ab68e4838f7eb
Publikováno v:
Stem Cell Research & Therapy, Vol 9, Iss 1, Pp 1-14 (2018)
Abstract Background Amyotrophic lateral sclerosis (ALS) represents a devastating, progressive, heterogeneous, and the most common motor neuron (MN) disease. To date, no cure has been available for the condition. Studies with transgenic mice have yiel
Externí odkaz:
https://doaj.org/article/f09d8e09d6144a44aa1e5e89c9d5f787
Autor:
Hong Chen, Wenjun Zhou, Yuting Ruan, Lei Yang, Ningning Xu, Rongping Chen, Rui Yang, Jia Sun, Zhen Zhang
Publikováno v:
Molecular Medicine, Vol 24, Iss 1, Pp 1-12 (2018)
Abstract Background Type 2 diabetes mellitus (T2DM) is characterized by pancreatic β-cell failure, which arises from metabolic stress and results in β cell dedifferentiation, leading to β-cell death. Pathological activation of the renin–angioten
Externí odkaz:
https://doaj.org/article/dfee6d2a1ca24696aff1a08664c7fac6
Publikováno v:
Cellular Physiology and Biochemistry, Vol 46, Iss 1, Pp 335-350 (2018)
Background/Aims: The islet is an important endocrine organ to secrete insulin to regulate the metabolism of glucose and maintain the stability of blood glucose. Long noncoding RNAs (lncRNAs) are involved in a variety of biological functions and play
Externí odkaz:
https://doaj.org/article/70ad1dd64a3343d9a0630dec45e70db2
Autor:
Myriam Fezai, Mohamed Jemaà, Hajar Fakhri, Hong Chen, Bhaeldin Elsir, Lisann Pelzl, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 40, Iss 5, Pp 1231-1238 (2016)
Background: The Na+,Cl- coupled creatine transporter CreaT (SLC6A8) is expressed in a variety of tissues including the brain. Genetic defects of CreaT lead to mental retardation with seizures. The present study explored the regulation of CreaT by the
Externí odkaz:
https://doaj.org/article/860be2e967ec4e9892d3ca49c4bc2cc5
Autor:
Guoxing Liu, Hang Cao, Guilai Liu, David Heinzmann, Hong Chen, Anja T. Umbach, Meinrad Gawaz, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 5, Pp 1695-1702 (2016)
Background/Aims: The polyamine oxidase inhibitor MDL-72527 (N1,N4-bis(2,3-butadienyl)-1,4-butanediamine) were expected to increase the abundance of spermine, a powerful inhibitor of platelet activation. Nothing is known, however, on the sensitivity o
Externí odkaz:
https://doaj.org/article/fa1d482c144c44e79d548e322f7b03a2
Autor:
Guoxing Liu, Guilai Liu, Madhumita Chatterjee, Anja T. Umbach, Hong Chen, Meinrad Gawaz, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 38, Iss 2, Pp 726-736 (2016)
Background/Aims: DAPT (24-diamino-5-phenylthiazole) inhibits γ-secretase, which cleaves the signaling molecule CD44, a negative regulator of platelet activation and apoptosis. CD44 is a co-receptor for macrophage migration inhibitory factor (MIF) an
Externí odkaz:
https://doaj.org/article/b23072ceb6f0498f95e7e7639a996df3
Autor:
Guoxing Liu, Guilai Liu, Hong Chen, Oliver Borst, Meinrad Gawaz, Andrea Vortkamp, Rainer Schreiber, Karl Kunzelmann, Florian Lang
Publikováno v:
Cellular Physiology and Biochemistry, Vol 37, Iss 5, Pp 1934-1944 (2015)
Background/Aims: The ubiquitously expressed Ca2+ Activated Cl- Channel Ano6 participates in the stimulation of cell membrane scrambling. Defective Ano6 underlies the Scott syndrome, an inherited bleeding disorder with impaired scrambling of plasma me
Externí odkaz:
https://doaj.org/article/27fff60997c74a58b754edd242bc5e21