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Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Background Paraptosis is a programmed cell death characterized by cytoplasmic vacuolation, which has been explored as an alternative method for cancer treatment and is associated with cancer resistance. However, the mechanisms underlying the
Externí odkaz:
https://doaj.org/article/dcc7e46d203d44c4b08ea7f9851b1c08
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Autophagy is a cellular self-degradation process that plays a crucial role in maintaining metabolic functions in cells and organisms. Dysfunctional autophagy has been linked to various diseases, including cancer. In cancer, dysregulated auto
Externí odkaz:
https://doaj.org/article/dbd4ff7ddede4c5f856e156e14789e11
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101694- (2024)
Crotonylation is an importantly conserved post-translational modification, which is completely different from acetylation. In recent years, it has been confirmed that crotonylation occurs on histone and non-histone. Crotonylated Histone primarily aff
Externí odkaz:
https://doaj.org/article/92c8d7fff7994525ae32884ea58c456c
Publikováno v:
Biochemistry and Biophysics Reports, Vol 38, Iss , Pp 101682- (2024)
Background: HtrA2, a pro-apoptotic protease, plays a crucial role in apoptosis by cleaving inhibitory and anti-apoptotic proteins by translocating from mitochondria to the cytosol. Prior studies in ischemic cells have indicated that cytosolic HtrA2 t
Externí odkaz:
https://doaj.org/article/0c959668146e4bd285b55e9d6922c42b
Autor:
Renata F. Saito, Camila Maria Longo Machado, Ana Luiza Oliveira Lomba, Andréia Hanada Otake, Maria Cristina Rangel
Publikováno v:
Applied Biosciences, Vol 3, Iss 1, Pp 45-58 (2024)
From an evolutive perspective, tumor cells endure successive turnover upon stress conditions and pressure to adapt to new environments. These cells use exceptional communication skills to share biological information to “survive upon every metaboli
Externí odkaz:
https://doaj.org/article/020744951cdd4e4694267983aef25b6e
Autor:
Ehsan Manouchehri Doulabi, Louise Dubois, Liza Löf, Tanay Kumar Sinha, George Mickhael Harinck, Per Stålhandske, Anders Larsson, Masood Kamali-Moghaddam
Publikováno v:
Biochemistry and Biophysics Reports, Vol 39, Iss , Pp 101761- (2024)
Extracellular vesicles (EVs), whose main subtypes are exosomes, microparticles, and apoptotic bodies, are secreted by all cells and harbor biomolecules such as DNA, RNA, and proteins. They function as intercellular messengers and, depending on their
Externí odkaz:
https://doaj.org/article/35ce1fbe1d4b47bda36e20d658396e61
Autor:
Mohammad Salehi, Mohammad Javad Kamali, Daniyal Arab, Naghme Safaeian, Zahra Ashuori, Moein Maddahi, Narges Latifi, Amir Moein Jahromi
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101644- (2024)
Exosomes are a type of extracellular vesicle that contains bioactive molecules that can be secreted by most cells. Nevertheless, the content of these cells differs depending on the cell from which they originate. The exosome plays a crucial role in m
Externí odkaz:
https://doaj.org/article/7c84ff3c5a164c4a904597db0b716823
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101625- (2024)
Globally cancer and Alzheimer's disease (AD) are two major diseases and still, there is no clearly defined molecular mechanism. There is an opposite relation between cancer and AD which are the proportion of emerging cancer was importantly slower in
Externí odkaz:
https://doaj.org/article/52f9347c196d4310acc40a61cc3ce90b
Autor:
Martina Muste Sadurni, Marco Saponaro
Publikováno v:
Applied Biosciences, Vol 2, Iss 3, Pp 459-476 (2023)
Deregulated transcription is a well-known characteristic of cancer cells, with differentially expressed genes being a common feature of several cancers. Often, deregulated transcription is a consequence of alterations in transcription factors (TFs),
Externí odkaz:
https://doaj.org/article/f8c0934d247a4455a935c06ce4a1edef
Autor:
Marvel Megaly, Anel Turgambayeva, Ryan D. Hallam, Gregory Foran, Mark Megaly, Aleksandar Necakov
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 234 (2024)
Drosophila melanogaster has been used as a model system to identify and characterize genetic contributions to development, homeostasis, and to investigate the molecular determinants of numerous human diseases. While there exist many differences at th
Externí odkaz:
https://doaj.org/article/dfa9494efdfb406499f355f0b69a045c