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Autor:
Junhui Liu, Huaicheng Wang, Qinyu Liu, Shushu Long, Yanfang Wu, Nengying Wang, Wei Lin, Gang Chen, Miao Lin, Junping Wen
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-29 (2024)
Abstract Background The anti-aging protein Klotho plays a protective role in kidney disease, but its potential as a biomarker for chronic kidney disease (CKD) is controversial. Additionally, the main pathways through which Klotho exerts its effects o
Externí odkaz:
https://doaj.org/article/02dbbc0cc28244529c988bf0292c1690
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Background Archetypical cross-β spines sharpen the boundary between functional and pathological proteins including β-amyloid, tau, α-synuclein and transthyretin are linked to many debilitating human neurodegenerative and non-neurodegenera
Externí odkaz:
https://doaj.org/article/32e28b8ac5054bbe98e4dbd2d5f5774d
Autor:
Niloufar Sadat Kalaki, Mozhgan Ahmadzadeh, Mohammad Najafi, Meysam Mobasheri, Hossein Ajdarkosh, Mohammad Hadi Karbalaie Niya
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101633- (2024)
Background: Colorectal cancer (CRC), is the third most prevalent cancer across the globe, and is often detected at advanced stage. Late diagnosis of CRC, leave the chemotherapy and radiotherapy as the main options for the possible treatment of the di
Externí odkaz:
https://doaj.org/article/d8057e3a0cbe4f7ebe7441387cc8d99d
Autor:
Tao He, Chong Lu, Wei Gong, Zhenjian Ge, Rongkang Li, Xinji Li, Chen Sun, Wentao Li, Qishan Long, Qiang Liu, Yongqing Lai
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 5, p 186 (2024)
Background: Clear cell renal cell carcinoma (ccRCC) is a prevalent malignant tumor affecting the urinary system. Due to its unfavorable prognosis, there is a pressing need to discover effective approaches for early diagnosis and treatment of ccRCC. E
Externí odkaz:
https://doaj.org/article/71451ad611a7446c9714ded9e372d612
Publikováno v:
Biochemistry and Biophysics Reports, Vol 36, Iss , Pp 101577- (2023)
Atrial fibrillation (AF) is a common arrhythmia in clinical practice, and its incidence is increasing year by year, which seriously affects the survival and prognosis of patients. In recent years, circRNAs has played an important role in the diagnosi
Externí odkaz:
https://doaj.org/article/0543e7ccd8d24b4dbb9b1ce31c1a0eec
Publikováno v:
Biochemistry and Biophysics Reports, Vol 36, Iss , Pp 101576- (2023)
Cadherin is a homophilic, Ca2+-dependent cell adhesion glycoprotein that mediates cell-cell adhesion. Among them, Cadherin-11 (CDH11), as a classical cadherin, participates in and influences many crucial aspects of human growth and development. Furth
Externí odkaz:
https://doaj.org/article/cc4dffe552fe46dd8c433b15652f0fa0
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Cysteinyl cathepsins (CTSs) are widely known to have a proteolysis function that mediates recycling of unwanted proteins in endosomes and lysosomes, and investigation of CTSs has greatly improved with advances in live-imaging techniques both
Externí odkaz:
https://doaj.org/article/be3d64ceadfa4eed9ff822ec305aa804
Autor:
Maolin Tang, Shisheng Zhao, Ling Ren, Qianqian Li, Li Li, Chaoli Wang, Chunmei Meng, Yuling Chen, Weimin Hu
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 138 (2024)
Background: Mounting evidence indicates that complement components play a crucial role in cancer progression. Recent findings indicate that certain complement components display a significant rise in expression within esophageal squamous cell carcino
Externí odkaz:
https://doaj.org/article/45440551cbe046a5ad8fc56adfc3b3e7
Autor:
Lulu Wang, Xiaowei Liu
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 87 (2024)
Background: The pituitary tumor-transforming gene 1 (PTTG1), also recognized as securin, plays a crucial role in diverse biological processes, such as restraining sister chromatid segregation, facilitating DNA repair, contributing to organ developmen
Externí odkaz:
https://doaj.org/article/c9afb1d1b556460aba05d6ae53654cd7
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 80 (2024)
The incidence and mortality from malignant tumors continue to rise each year. Consequently, early diagnosis and intervention are vital for improving patient’ prognosis and survival. The traditional pathological tissue biopsy is currently considered
Externí odkaz:
https://doaj.org/article/db9578430fa443bc8cb69264cf38c4d4