Zobrazeno 1 - 10
of 70
pro vyhledávání: '"133"'
Autor:
Luís Cláudio Lima De Jesus, Mariana Martins Drumond, André de Carvalho, Spencer S. Santos, Flaviano S. Martins, Ênio Ferreira, Renata Salgado Fernandes, André Luís Branco de Barros, Fillipe L.R. do Carmo, Pablo F. Perez, Vasco Azevedo, Pamela Mancha-Agresti
Publikováno v:
Journal of Functional Foods, Vol 53, Iss , Pp 197-207 (2019)
Mucositis is a cytotoxic side effect caused by chemotherapy drugs, such as 5-Fluorouracil (5-FU), being a serious clinical issue. Lactobacillus spp. could be a helpful strategy to alleviate 5-FU chemotherapy-caused intestinal damage, due to their abi
Externí odkaz:
https://doaj.org/article/fcb0d5cd36bc49e2b9c5dab99299452c
Autor:
Azevedo Orleâncio Gomes R, Oliveira Renato André C, Oliveira Bruna, Zaja-Milatovic Snjezana, Araújo Celina, Wong Deysi Viviana T, Costa Tiê, Lucena Herene Barros, Lima-Júnior Roberto César P, Ribeiro Ronaldo A, Warren Cirle A, Lima Aldo Ângelo M, Vitek Michael P, Guerrant Richard L, Oriá Reinaldo B
Publikováno v:
BMC Gastroenterology, Vol 12, Iss 1, p 35 (2012)
Abstract Background Intestinal mucositis is one of the major troublesome side effects of anticancer chemotherapy leading to poor patient compliance. In this study we addressed the role of the novel apolipoprotein E (ApoE) COG 133 mimetic peptide in 5
Externí odkaz:
https://doaj.org/article/64bd1202923f441bbaeb6d7b84d8f4ce
Autor:
Bruno Gagnon, Jessica Murphy, David Simonyan, Claudia A. Penafuerte, Jacinthe Sirois, Martin Chasen, Michel L. Tremblay
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 3, Pp 1041-1053 (2024)
Abstract Background The interdependence of cytokines and appetite‐modifying hormones implicated in cancer anorexia‐cachexia syndrome (CACS) remains unclear. This study aimed to regroup these cytokines and hormones into distinct inflammatory (or n
Externí odkaz:
https://doaj.org/article/f424e884f58d4690b2085425d47f08b2
Autor:
Cindy Gunawan, Charlotte Fleming, Peter J. Irga, Roong Jien Wong, Rose Amal, Fraser R. Torpy, S. Mojtaba Golzan, Kristine C. McGrath
Publikováno v:
Environment International, Vol 185, Iss , Pp 108512- (2024)
Background: Sporadic Alzheimer’s disease (AD) occurs in 99% of all cases and can be influenced by air pollution such as diesel emissions and more recently, an iron oxide particle, magnetite, detected in the brains of AD patients. However, a mechani
Externí odkaz:
https://doaj.org/article/8e6ba0d8388645eab94d8d0a712bfc7a
Autor:
Julie Z. Brouillet, Margherita Boltri, Aiste Lengvenyte, Mohamed Lajnef, Jean-Romain Richard, Caroline Barrau, Robertas Strumila, Manon Coyac, Ching-Lien Wu, Wahid Boukouaci, Sobika Sugunasabesan, Jihène Bouassida, Sébastien Guillaume, Maude Sénèque, Emilie Olié, Marion Leboyer, Philippe Courtet, Ryad Tamouza
Publikováno v:
Journal of Affective Disorders Reports, Vol 14, Iss , Pp 100624- (2023)
Background: Patients with major mood disorders are at high risk of suicidal behavior compared to the general population. Suicide is a public health concern, accounting for around 1.2% of deaths worldwide. Understanding its underlying mechanisms may h
Externí odkaz:
https://doaj.org/article/7298f7e0ad534c9a9882909df4dcc9cb
Autor:
Temesgen E. Andargie, Katerina Roznik, Neelam Redekar, Tom Hill, Weiqiang Zhou, Zainab Apalara, Hyesik Kong, Oren Gordon, Rohan Meda, Woojin Park, Trevor S. Johnston, Yi Wang, Sheila Brady, Hongkai Ji, Jack A. Yanovski, Moon K. Jang, Clarence M. Lee, Andrew H. Karaba, Andrea L. Cox, Sean Agbor-Enoh
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Multisystem inflammatory syndrome in children (MIS-C) is a rare but life-threatening hyperinflammatory condition induced by infection with severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) that causes pediatric COVID-19 (pCOVID-19). The re
Externí odkaz:
https://doaj.org/article/9dcf9edb519d4585810c8ca21afed2eb
Autor:
Zhengping Huang, Kailey E. Brodeur, Liang Chen, Du, Holly Wobma, Evan E. Hsu, Meng Liu, Joyce C. Chang, Margaret H. Chang, Janet Chou, Megan Day-Lewis, Fatma Dedeoglu, Olha Halyabar, James A. Lederer, Tianwang Li, Mindy S. Lo, Meiping Lu, Esra Meidan, Jane W. Newburger, Adrienne G. Randolph, Mary Beth Son, Robert P. Sundel, Maria L. Taylor, Huaxiang Wu, Qing Zhou, Scott W. Canna, Kevin Wei, Lauren A. Henderson, Peter A. Nigrovic, Pui Y. Lee
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
BACKGROUND Macrophage activation syndrome (MAS) is a life-threatening complication of Still’s disease (SD) characterized by overt immune cell activation and cytokine storm. We aimed to further understand the immunologic landscape of SD and MAS.METH
Externí odkaz:
https://doaj.org/article/81b3a17577a741b6be6230b306b10f60
Autor:
Huai-Chia Chuang, Chia-Hsin Hsueh, Pu-Ming Hsu, Ching-Yi Tsai, Ying-Chun Shih, Hsien-Yi Chiu, Yi-Ming Chen, Wen-Kuang Yu, Ming-Han Chen, Tse-Hua Tan
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
Dual-specificity phosphatase 8 (DUSP8) is a MAPK phosphatase that dephosphorylates and inactivates the kinase JNK. DUSP8 is highly expressed in T cells; however, the in vivo role of DUSP8 in T cells remains unclear. Using T cell–specific Dusp8 cond
Externí odkaz:
https://doaj.org/article/f37e99b47c2e42e8982271f79bee0148
Autor:
Emely L. Verweyen, Kairavee Thakkar, Sanjeev Dhakal, Elizabeth Baker, Kashish Chetal, Daniel Schnell, Scott Canna, Alexei A. Grom, Nathan Salomonis, Grant S. Schulert
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 22 (2023)
Systemic autoimmune and autoinflammatory diseases are characterized by genetic and cellular heterogeneity. While current single-cell genomics methods provide insights into known disease subtypes, these analysis methods do not readily reveal novel cel
Externí odkaz:
https://doaj.org/article/d5179c6c7e644a40aec238db94ea243c
Autor:
Guillaume Blot, Rémi Karadayi, Lauriane Przegralek, Thérèse-Marie Sartoris, Hugo Charles-Messance, Sébastien Augustin, Pierre Negrier, Frédéric Blond, Frida Paulina Muñiz-Ruvalcaba, David Rivera-de la Parra, Lucile Vignaud, Aude Couturier, José-Alain Sahel, Niyazi Acar, Aida Jimenez-Corona, Cécile Delarasse, Yonathan Garfias, Florian Sennlaub, Xavier Guillonneau
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 19 (2023)
Type 2 diabetes mellitus (T2DM), characterized by hyperglycemia and dyslipidemia, leads to nonproliferative diabetic retinopathy (NPDR). NPDR is associated with blood-retina barrier disruption, plasma exudates, microvascular degeneration, elevated in
Externí odkaz:
https://doaj.org/article/a428d0dd6e824e1eaa04dc9d73afec22