Zobrazeno 1 - 10
of 53
pro vyhledávání: ''
Autor:
Qinhao Wang, Yuanyuan Su, Ruiqi Sun, Xin Xiong, Kai Guo, Mengying Wei, Guodong Yang, Yi Ru, Zhengxiang Zhang, Jing Li, Jing Zhang, Qing Qiao, Xia Li
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract Background The enrichment of peri-cancerous adipose tissue is a distinctive feature of colorectal cancer (CRC), accelerating disease progression and worsening prognosis. The communication between tumor cells and adjacent adipocytes plays a c
Externí odkaz:
https://doaj.org/article/c6c9723a741d47ae815822ef335e3410
Autor:
Martina Lepore Signorile, Candida Fasano, Giovanna Forte, Katia De Marco, Paola Sanese, Vittoria Disciglio, Elisabetta Di Nicola, Antonino Pantaleo, Cristiano Simone, Valentina Grossi
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-20 (2023)
Abstract Background Activation of the Wnt pathway has been linked to colorectal cancer (CRC). Previous reports suggest that Wnt3a can activate p38. Besides, p38α feeds into the canonical Wnt/β-catenin pathway by inhibiting GSK3β through phosphoryl
Externí odkaz:
https://doaj.org/article/b1012b50cb79450496cd287a38de5e67
Publikováno v:
The Ukrainian Biochemical Journal, Vol 95, Iss 6, Pp 64-72 (2023)
Colorectal cancer is one of the leading causes of mortality in the world. The search for new methods of therapy for this disease that could correct the state of oxidative stress during the development of neoplasms is up to date. The aim of this work
Externí odkaz:
https://doaj.org/article/cf278da27a0e48e4be860d49ef62cf5d
Autor:
Niloufar Sadat Kalaki, Mozhgan Ahmadzadeh, Mohammad Najafi, Meysam Mobasheri, Hossein Ajdarkosh, Mohammad Hadi Karbalaie Niya
Publikováno v:
Biochemistry and Biophysics Reports, Vol 37, Iss , Pp 101633- (2024)
Background: Colorectal cancer (CRC), is the third most prevalent cancer across the globe, and is often detected at advanced stage. Late diagnosis of CRC, leave the chemotherapy and radiotherapy as the main options for the possible treatment of the di
Externí odkaz:
https://doaj.org/article/d8057e3a0cbe4f7ebe7441387cc8d99d
Autor:
Zhenyu Xie, Liaoran Niu, Gaozan Zheng, Kunli Du, Songchen Dai, Ruikai Li, Hanjun Dan, Lili Duan, Hongze Wu, Guangming Ren, Xinyu Dou, Fan Feng, Jian Zhang, Jianyong Zheng
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract The role of mast cells (MCs) in colorectal cancer (CRC) remains unclear, and a comprehensive single-cell study on CRC MCs has not been conducted. This study used a multi-omics approach, integrating single-cell sequencing, spatial transcripto
Externí odkaz:
https://doaj.org/article/8be01300fcfc46e8a8891e2889598206
Autor:
Ting Wang, Longci Sun, Chengkun Chen, Yingchao Zhang, Baoyu He, Yanhua Zhang, Zhenghe Wang, Hanbing Xue, Yujun Hao
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-15 (2023)
Abstract Background PI3K/AKT signaling pathway plays important role in tumorigenesis of human cancer. Protein phosphorylation is crucial for signaling transduction of this pathway. PIK3CA, encoding the catalytic subunit p110α of PI3K complex, is one
Externí odkaz:
https://doaj.org/article/7e2775013f4a4ef3bd9add2c49288dfc
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 245 (2024)
Background: Improving the clinical outcome of colorectal cancer (CRC) patients remains a major challenge. This study aimed to develop a new predictive classifier for CRC and to examine its relationship with the immune environment and therapeutic resp
Externí odkaz:
https://doaj.org/article/b74fa49a12104c849e5c2b3f30ae6b6a
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 7, p 272 (2024)
The p53, a pivotal tumor suppressor, regulates various cellular responses, including DNA repair and apoptosis. Normally, p53 levels are low due to murine double minute clone 2 (MDM2) mediated polyubiquitination. However, stress signals disrupt p53-MD
Externí odkaz:
https://doaj.org/article/517dd98177994059b80c287b11e9bbda
Publikováno v:
Biochemistry and Biophysics Reports, Vol 36, Iss , Pp 101572- (2023)
Colorectal cancer (CRC), classified as a lethal form of cancer, substantially threatens human well-being. Cancer stem cells (CSCs) reflect subsets for cancerous cells having basic stem-cell type properties, being significantly involved in the develop
Externí odkaz:
https://doaj.org/article/69d3b1c15b2d4976a1b57dfe81a67b65
Autor:
Mujie Ye, Jinhao Chen, Feiyu Lu, Minghui Zhao, Suwen Wu, Chunhua Hu, Ping Yu, Jingbao Kan, Jianan Bai, Ye Tian, Qiyun Tang
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-16 (2023)
Abstract Background N6-methyladenosine (m6A) modification is the most abundant reversible methylation modification in eukaryotes, and it is reportedly closely associated with a variety of cancers progression, including colorectal cancer (CRC). This s
Externí odkaz:
https://doaj.org/article/0fdd6ee2cce940408541e7049bc4db79