Zobrazeno 1 - 10
of 36
pro vyhledávání: '"35"'
Autor:
Vivian P. Bykerk, Andrew Blauvelt, Jeffrey R. Curtis, Cécile Gaujoux‐Viala, Tore K. Kvien, Kevin Winthrop, Nicola Tilt, Christina Popova, Xavier Mariette, Boulos Haraoui
Publikováno v:
ACR Open Rheumatology, Vol 3, Iss 8, Pp 501-511 (2021)
Objective To investigate the impact of baseline and time‐varying factors on the risk of serious adverse events (SAEs) in patients during long‐term certolizumab pegol (CZP) treatment. Methods Safety data were pooled across 34 CZP clinical trials i
Externí odkaz:
https://doaj.org/article/bc65d43bb8c340d5b0b51aece614f660
Autor:
Sophia E. Chrysostomou, Sandra Eder, Isabella Pototschnig, Anna‐Lena Mayer, Martina Derler, Marion Mussbacher, Silvia Schauer, Dongxu Zhang, Dongmei Yan, Gennie Liu, Gerald Hoefler, Thomas Weichhart, Paul W. Vesely, Lingbing Zhang, Martina Schweiger
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 15, Iss 2, Pp 562-574 (2024)
Abstract Background Cancer‐associated cachexia (CAC) is a debilitating syndrome associated with poor quality of life and reduced life expectancy of cancer patients. CAC is characterized by unintended body weight reduction due to muscle and adipose
Externí odkaz:
https://doaj.org/article/900272734f5246308cda047cdd899863
Publikováno v:
ACR Open Rheumatology, Vol 6, Iss 2, Pp 72-80 (2024)
Objective To assess tofacitinib and self‐injectable tumor necrosis factor inhibitor (TNFi) adherence using the Medication Event Monitoring System (MEMS) and characterize association with adherence in patients with rheumatoid arthritis (RA). Methods
Externí odkaz:
https://doaj.org/article/9dfcaf4e73764985968014ed26046a98
Skeletal muscle analysis of cancer patients reveals a potential role for carnosine in muscle wasting
Autor:
Dheeraj Kumar Posa, Janice Miller, David Hoetker, Michael I. Ramage, Hong Gao, Jingjing Zhao, Benjamin Doelling, Aruni Bhatnagar, Stephen J. Wigmore, Richard J.E. Skipworth, Shahid P. Baba
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 4, Pp 1802-1814 (2023)
Abstract Background Muscle wasting during cancer cachexia is mediated by protein degradation via autophagy and ubiquitin‐linked proteolysis. These processes are sensitive to changes in intracellular pH ([pH]i) and reactive oxygen species, which in
Externí odkaz:
https://doaj.org/article/c02fd9a25f77491299b8f06183dad31a
Autor:
Paulo V.G. Alabarse, Priscila S. Lora, Jordana M.S. Silva, Rafaela C.E. Santo, Eduarda C. Freitas, Mayara S. deOliveira, Andrelise S. Almeida, Mônica Immig, Vivian O.N. Teixeira, Lidiane I. Filippin, Ricardo M. Xavier
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 9, Iss 3, Pp 603-612 (2018)
Abstract Background Rheumatoid arthritis is characterized by chronic polyarticular synovitis and presents systemic changes that impact quality of life, such as impaired muscle function, seen in up to 66% of the patients. This can progress to severely
Externí odkaz:
https://doaj.org/article/744441f74aef4eb0abab6b5f0e02c496
Autor:
Wenshuang Zhang, Yufeng Ge, Yandong Liu, Yi Yuan, Jian Geng, Fengyun Zhou, Pengju Huang, Jia Shi, Kangkang Ma, Zitong Cheng, Glen M. Blake, Minghui Yang, Xinbao Wu, Xiaoguang Cheng, Ling Wang
Publikováno v:
JBMR Plus, Vol 7, Iss 12, Pp n/a-n/a (2023)
ABSTRACT Older women with a first hip fracture exhibit heightened susceptibility and incidence of second fracture and potentially severe consequences. This prospective study was to compare the predictive power of qualitative and quantitative muscle p
Externí odkaz:
https://doaj.org/article/453a4e713937427b80d72d1e7b8a010d
Autor:
Sebastian Zanner, Elliott Goff, Samuel Ghatan, Eva Maria Wölfel, Charlotte Ejersted, Gisela Kuhn, Ralph Müller, Morten Frost
Publikováno v:
JBMR Plus, Vol 7, Iss 11, Pp n/a-n/a (2023)
ABSTRACT Clinical studies indicate that microvascular disease (MVD) affects bone microstructure and decreases bone strength in type 2 diabetes mellitus (T2D). Osteocytes are housed in small voids within the bone matrix and lacunae and act as sensors
Externí odkaz:
https://doaj.org/article/ae2a4857ac274e308fa19cb33a56fc32
Publikováno v:
Rheumatology & Autoimmunity, Vol 3, Iss 2, Pp 120-124 (2023)
Abstract Introduction Thrombocytopenia, a common noncriteria manifestation of antiphospholipid syndrome (APS), is severe in approximately one‐third of patients with APS. However, there are no guidelines for treating such thrombocytopenia. B‐cell
Externí odkaz:
https://doaj.org/article/e782f061b1334821855880e3799b1edc
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 706-729 (2023)
Abstract Anorexia/appetite loss in older subjects is frequently underrecognized in clinical practice, which may reflect deficient understanding of clinical sequelae. Therefore, we performed a systematic literature review to assess the morbidity and m
Externí odkaz:
https://doaj.org/article/3715c04f3d714f6c907f5f94040a9cd7
Publikováno v:
Journal of Cachexia, Sarcopenia and Muscle, Vol 14, Iss 2, Pp 684-696 (2023)
Abstract We aimed to quantify declines from baseline in lower limb skeletal muscle size and strength of uninjured adults following single‐leg disuse. We searched EMBASE, Medline, CINAHL, and CCRCT up to 30 January 2022. Studies were included in the
Externí odkaz:
https://doaj.org/article/6f2b75f3209049d08226e8aad4f60915