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Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Leptospirosis is a worldwide zoonosis caused by pathogenic Leptospira spp. having more than 300 serovars. These serovars can infect a variety of hosts, some being asymptomatic carriers and others showing varied symptoms of mild to severe infection. S
Externí odkaz:
https://doaj.org/article/bb0234b6dd4046e781c94a73f8580f76
Autor:
Anna Kertisová, Lenka Žáková, Kateřina Macháčková, Aleš Marek, Pavel Šácha, Petr Pompach, Jiří Jiráček, Irena Selicharová
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
The insulin receptor (IR, with its isoforms IR-A and IR-B) and the insulin-like growth factor 1 receptor (IGF-1R) are related tyrosine kinase receptors. Recently, the portfolio of solved hormone–receptor structures has grown extensively thanks to a
Externí odkaz:
https://doaj.org/article/85854c8c7ff941429cf6951fa7321724
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Heterochromatin is a gene-repressive protein–nucleic acid ultrastructure that is initially nucleated by DNA sequences. However, following nucleation, heterochromatin can then propagate along the chromatin template in a sequence-independent manner i
Externí odkaz:
https://doaj.org/article/f1c2113b023146afb564dcc3391fdb98
Autor:
Tamara Z. Ishwarlall, Victoria T. Adeleke, Leah Maharaj, Moses Okpeku, Adebayo A. Adeniyi, Matthew A. Adeleke
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Buruli ulcer (BU) is a neglected tropical disease. It is caused by the bacterium Mycobacterium ulcerans and is characterized by skin lesions. Several studies were performed testing the Bacillus Calmette-Guérin (BCG) vaccine in human and animal model
Externí odkaz:
https://doaj.org/article/b8226adaddc546a0a70d915791c434f5
Autor:
Xiakun Chu, Jin Wang
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Cell cycle is known to be regulated by the underlying gene network. Chromosomes, which serve as the scaffold for gene expressions, undergo significant structural reorganizations during mitosis. Understanding the mechanism of the cell cycle from the c
Externí odkaz:
https://doaj.org/article/da62b9e4426844c2b4df9de81dff7bde
Autor:
Tania Martins-Marques, Katja Witschas, Ilda Ribeiro, Mónica Zuzarte, Steve Catarino, Teresa Ribeiro-Rodrigues, Francisco Caramelo, Trond Aasen, Isabel Marques Carreira, Lino Goncalves, Luc Leybaert, Henrique Girao
Publikováno v:
Open Biology, Vol 13, Iss 11 (2023)
Classically associated with gap junction-mediated intercellular communication, connexin43 (Cx43) is increasingly recognized to possess non-canonical biological functions, including gene expression regulation. However, the mechanisms governing the loc
Externí odkaz:
https://doaj.org/article/9818ae85d1f1418e970836550652bf2d
Autor:
Alberto Ribes-Navarro, Naoki Kabeya, L. Filipe C. Castro, André Gomes-dos-Santos, Miguel M. Fonseca, Hilke Alberts-Hubatsch, Francisco Hontoria, Juan C. Navarro, Óscar Monroig
Publikováno v:
Open Biology, Vol 13, Iss 10 (2023)
Previous data revealed the unexpected presence of genes encoding for long-chain polyunsaturated fatty acid (LC-PUFA) biosynthetic enzymes in transcriptomes from freshwater gammarids but not in marine species, even though closely related species were
Externí odkaz:
https://doaj.org/article/1097cf7b17ac46c09c103cfba1087c34
Autor:
Tiziana Pecchillo Cimmino, Ester Pagano, Mariano Stornaiuolo, Gabriella Esposito, Rosario Ammendola, Fabio Cattaneo
Publikováno v:
Open Biology, Vol 13, Iss 10 (2023)
The human formyl-peptide receptor 2 (FPR2) is activated by an array of ligands. By phospho-proteomic analysis we proved that FPR2 stimulation induces redox-regulated phosphorylation of many proteins involved in cellular metabolic processes. In this s
Externí odkaz:
https://doaj.org/article/7b18e3c4ca0f4f3fa01b364e3c354996
Autor:
Julia M. York
Publikováno v:
Open Biology, Vol 13, Iss 10 (2023)
Antarctic notothenioid fishes (cryonotothenioids) live in waters that range between −1.86°C and an extreme maximum +4°C. Evidence suggests these fish sense temperature peripherally, but the molecular mechanism of temperature sensation in unknown.
Externí odkaz:
https://doaj.org/article/414bfbe89a364502882f930fe017c7c0
Autor:
E. A. V. Burioli, M. Hammel, E. Vignal, J. Vidal-Dupiol, G. Mitta, F. Thomas, N. Bierne, D. Destoumieux-Garzón, G. M. Charrière
Publikováno v:
Open Biology, Vol 13, Iss 10 (2023)
Transmissible cancer cell lines are rare biological entities giving rise to diseases at the crossroads of cancer and parasitic diseases. These malignant cells have acquired the amazing capacity to spread from host to host. They have been described on
Externí odkaz:
https://doaj.org/article/69ff3cda4b204557acc799e05bf66b71