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Autor:
Daniel García-Ruano, Akanksha Jain, Zachary J. Heins, Brandon G. Wong, Ezira Yimer Wolle, Ahmad S. Khalil, Damien Coudreuse
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Experimental evolution using fast-growing unicellular organisms is a unique strategy for deciphering the principles and mechanisms underlying evolutionary processes as well as the architecture and wiring of basic biological functions. Over the past d
Externí odkaz:
https://doaj.org/article/1f899f63174046588bdae0d1a6b7db4d
Autor:
Atsushi Ueda, Abigayle Berg, Tashmit Khan, Madeleine Ruzicka, Shuwen Li, Ellyn Cramer, Atulya Iyengar, Chun-Fang Wu
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Drosophila courtship studies have elucidated several principles of the neurogenetic organization of complex behaviour. Through an integration across sensory modalities, males perform stereotypic patterns of chasing, courtship song production and copu
Externí odkaz:
https://doaj.org/article/17283145afcd4e298a0835d79a716d56
Autor:
Virginie Emond-Fraser, Myreille Larouche, Peter Kubiniok, Éric Bonneil, Jingjing Li, Mohammed Bourouh, Laura Frizzi, Pierre Thibault, Vincent Archambault
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Mitotic exit requires the dephosphorylation of many proteins whose phosphorylation was needed for mitosis. Protein phosphatase 2A with its B55 regulatory subunit (PP2A-B55) promotes this transition. However, the events and substrates that it regulate
Externí odkaz:
https://doaj.org/article/46c5647d8ab94946bf8a93207ca94ba5
Autor:
Salma Haniffa, Priyam Narain, Michelle Ann Hughes, Aleksa Petković, Marko Šušić, Vongai Mlambo, Dipesh Chaudhury
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Chronic social stress in mice causes behavioural and physiological changes that result in perturbed rhythms of body temperature, activity and sleep-wake cycle. To further understand the link between mood disorders and temperature rhythmicity in mice
Externí odkaz:
https://doaj.org/article/5e8dab44f23b478b994c8415e1fd59ef
Mutant SPART causes defects in mitochondrial protein import and bioenergetics reversed by Coenzyme Q
Autor:
Chiara Diquigiovanni, Nicola Rizzardi, Antje Kampmeier, Irene Liparulo, Francesca Bianco, Bianca De Nicolo, Erica Cataldi-Stagetti, Elisabetta Cuna, Giulia Severi, Marco Seri, Miriam Bertrand, Tobias B. Haack, Adela Della Marina, Frederik Braun, Romana Fato, Alma Kuechler, Christian Bergamini, Elena Bonora
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Pathogenic variants in SPART cause Troyer syndrome, characterized by lower extremity spasticity and weakness, short stature and cognitive impairment, and a severe mitochondrial impairment. Herein, we report the identification of a role of Spartin in
Externí odkaz:
https://doaj.org/article/3a2f4d216a754efba99fc06b6d4bfab0
Autor:
Cesar Camilo Prado Sepulveda, Rodrigo Maciel Alencar, Rosa Amélia Santana, Igor Belém de Souza, Gigliola Mayra Ayres D'Elia, Raquel Soares Maia Godoy, Ana Paula Duarte, Stefanie Costa Pinto Lopes, Marcus Vinicius Guimarães de Lacerda, Wuelton Marcelo Monteiro, Rafael Nacif-Pimenta, Nágila Francinete Costa Secundino, Leonardo Barbosa Koerich, Paulo Filemon Paolucci Pimenta
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Anophelines are vectors of malaria, the deadliest disease worldwide transmitted by mosquitoes. The availability of genomic data from various Anopheles species allowed evolutionary comparisons of the immune response genes in search of alternative vect
Externí odkaz:
https://doaj.org/article/65863fed39394d549f4f48e1245459d8
Autor:
M. Berni, J. Mota, D. Bressan, L. Ribeiro, G. Martins, J. Pereira, I. Ramos, R. Nunes-da-Fonseca, H. Araujo
Publikováno v:
Open Biology, Vol 13, Iss 7 (2023)
Dorsal–ventral (DV) patterning is regulated by the bone morphogenetic pathway (BMP) in Bilateria. In insect DV patterning, the Toll pathway also plays a role, in addition to BMPs. Variations in the relative importance of each pathway for DV pattern
Externí odkaz:
https://doaj.org/article/5e6c6fc1a72648aca89d5c925f86cc0b
Autor:
Francesca Sara Colizzi, Jan A. Veenstra, Gustavo L. Rezende, Charlotte Helfrich-Förster, David Martínez-Torres
Publikováno v:
Open Biology, Vol 13, Iss 6 (2023)
The neuropeptide pigment-dispersing factor (PDF) plays a pivotal role in the circadian clock of most Ecdysozoa and is additionally involved in the timing of seasonal responses of several photoperiodic species. The pea aphid, Acyrthosiphon pisum, is a
Externí odkaz:
https://doaj.org/article/f48925c93e45454d88671e91d8d3f7e5
Publikováno v:
Open Biology, Vol 13, Iss 6 (2023)
Adhesion between cells and the extracellular matrix is mediated by heterodimeric (αβ) integrin receptors that are intracellularly linked to the contractile actomyosin machinery. One of the proteins that control this link is talin, which organizes c
Externí odkaz:
https://doaj.org/article/b147206a1b06497fbd4dc1bb19c95fc0
Autor:
Mireia Medrano, Wissal Allaoui, Mathias Van Bulck, Sofie Thys, Leila Makrini-Maleville, Eve Seuntjens, Winnok H. De Vos, Emmanuel Valjent, Bálazs Gaszner, Ann Van Eeckhaut, Ilse Smolders, Dimitri De Bundel
Publikováno v:
Open Biology, Vol 13, Iss 6 (2023)
Neuromedin U (NMU) is an evolutionary conserved neuropeptide that has been implicated in multiple processes, such as circadian regulation, energy homeostasis, reward processing and stress coping. Although the central expression of NMU has been addres
Externí odkaz:
https://doaj.org/article/26de393b757b43169dd0b8e8bb418d2a