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Autor:
Aminetou Taleb Brahim, Mariem Taleb, Harouna Soumaré, Sidi Mohamed Ghaber, Aminetou Mohamed, Ali Ould Mohamed Salem Boukhary
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 16, Iss 2, p 11 (2024)
Background: Sickle cell disease (SCD) is a major heritable genetic disease in sub-Saharan Africa, including Mauritania. Fetal hemoglobin (HbF) can affect the pathophysiology, moderate the clinical course, and offer prospects for curative treatment of
Externí odkaz:
https://doaj.org/article/89c44b45222042b883f1a1cdcda09f5a
Autor:
Corrado Angelini
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 16, Iss 2, p 12 (2024)
Several inherited metabolic fatty acid disorders present with myopathies. Skeletal muscle accounts for 40% of the body and is important for metabolism, exercise, and movement. Muscle energy failure is manifested by metabolic crises with muscle weakne
Externí odkaz:
https://doaj.org/article/1666618be12c4e649b126d34104391a8
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 16, Iss 2, p 13 (2024)
Externí odkaz:
https://doaj.org/article/0099c24cb8c6458d8ad4ff6494edd6e2
Autor:
Hugo Aguilar-Díaz, Rosa Estela Quiroz-Castañeda, Daniela Ríos-Jasso, Raquel Cossío-Bayúgar, Estefan Miranda-Miranda
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 238 (2024)
Background: Hormone receptors exert their function through binding with their ligands, which results in cellular signaling activation mediated by genomic or non-genomic mechanisms. The intrinsic molecular communication of tick Rhipicephalus microplus
Externí odkaz:
https://doaj.org/article/0aab9cbc9f3649cb98b7612bfcb13f11
Autor:
Zhenxin Huo, Dawei Li, Kaihui Zhang, Bingshan Yan, Tongxing Zhang, Zhenhua Li, Shengbo Huang, Yue Liu, Baoshan Xu
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 224 (2024)
Background: The objective of this research was to identify differentially expressed genes (DEGs) related to ferroptosis in the annulus fibrosus (AF) during intervertebral disc degeneration (IDD). Methods: We analyzed gene data from degenerated and no
Externí odkaz:
https://doaj.org/article/10de5b2f65b74d26a59220aff4df4b9b
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 214 (2024)
Background: The senescence marker protein 30 (SMP30) is a calcium-binding protein whose expression decreases with age, and is closely associated with hepatocellular carcinoma (HCC) development. The primary goal of this study was to examine the mechan
Externí odkaz:
https://doaj.org/article/1cad1b9af7d94aedacb88a0ea4ff819d
Autor:
Hua Guan, Le Wang, Zhanyi Geng, Bowen Duan, Yang Gao, Zheyong Liang, Xinglong Zheng, Tao Shi, Fengwei Guo
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 236 (2024)
Background: This study aimed to elucidate the molecular mechanism through which C1q/tumor necrosis factor (TNF)-related protein 9 (CTRP9) acts in the formation and differentiation of brown adipose tissue (BAT). Methods: Adenovirus particles encoding
Externí odkaz:
https://doaj.org/article/19dbe21ad77341f7847366024146e925
Autor:
Guangjin Gu, Huaqi Yu, Huishuang Zou, Wenjuan Kou, Pingping Zhang, Guangjie Gu, Jie Lu, Weihan Shi, Pengcheng Chu, Yaning Zhang, Guangwei Sun, Jun Shang
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 210 (2024)
Traumatic spinal cord injury (SCI) is a serious disease of the central nervous system. Aside from the limited intrinsic regenerative capacity of neurons, complex microenvironmental disturbances can also lead to further cellular damage and growth inhi
Externí odkaz:
https://doaj.org/article/1405151bbb4145178ff53e249c0219cd
Autor:
Allan John R. Barcena, Archana Mishra, Dominic Karl M. Bolinas, Benjamin M. Martin, Marites P. Melancon
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 228 (2024)
Mesenchymal stem/stromal cells (MSCs) have emerged as a promising therapeutic approach for a variety of diseases due to their immunomodulatory and tissue regeneration capabilities. Despite their potential, the clinical application of MSC therapies is
Externí odkaz:
https://doaj.org/article/1cfd1578139b468699bb9bc852082473
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 229 (2024)
Neuroinflammation has emerged as a shared molecular mechanism in epilepsy and cognitive impairment, offering new insights into the complex interplay between immune responses and brain function. Evidence reveals involvement of High mobility group box
Externí odkaz:
https://doaj.org/article/188ccb428fec46b7ac50571962e1dfb9