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Autor:
Alexander Blagov, Anton Postnov, Vasily Sukhorukov, Mikhail Popov, Jamol Uzokov, Alexander Orekhov
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 36 (2024)
Parkinson’s disease (PD) is characterized by the degeneration of the dopaminergic neurons of the corpus striatum, which can be caused by the disruption of processes of mitochondrial homeostasis, including mitophagy, mitochondrial fusion and divisio
Externí odkaz:
https://doaj.org/article/b440d311b69043d6aca5404e8e115997
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 4 (2024)
Background: The current standard for Parkinson’s disease (PD) diagnosis is often imprecise and expensive. However, the dysregulation patterns of microRNA (miRNA) hold potential as a reliable and effective non-invasive diagnosis of PD. Methods: We u
Externí odkaz:
https://doaj.org/article/58d8d8345a5f4baa87d820c61ebf83e0
Autor:
Jozef Nahalka
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 11, p 292 (2023)
Background: As a chronic degenerative disorder of the central nervous system that affects both motor and non-motor systems, Parkinson’s disease (PD) is very complex, and explanations and models are needed to better understand how dopaminergic neuro
Externí odkaz:
https://doaj.org/article/64a10c79d6d54be6a76edf2b8d562ffc
Autor:
Richard H. W. Funk, Manfred Fähnle
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 13, Iss 2, Pp 181-189 (2021)
This study reviews the use of magnetic and electromagnetic fields (EMF), pulsed electromagnetic fields (PEMF), and transcranial magnetic stimulation (TMS) in Parkinson’s disease, Alzheimer’s disease (AD), or Multiple Sclerosis (MS). The Introduct
Externí odkaz:
https://doaj.org/article/81cf3973ed714f1c9fbeb63d1c515bac
Autor:
Shaswati Sarma, Shiny Derose, Nagamaniammai Govindarajan, Musthafa Mohamed Essa, M. Walid Qoronfleh, Saravana Babu Chidambaram, Buthaina Al-Bulushi
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 13, Iss 2, Pp 131-140 (2021)
Coenzyme Q10 (CoQ10) is an antioxidant, fat-soluble component present in the mitochondrial cells. It provides beneficial results in the treatment of male infertility. In the current scenario, the sedative lifestyle, diet and stress in human lead to e
Externí odkaz:
https://doaj.org/article/c95acad6fbee4d32bf9122fe7e51fcb2
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 12, Pp 1503-1512 (2021)
Introduction: Parkinson’s disease (PD) is caused by the interplay of genetic and environmental factors during brain aging. About 90 single nucleotide polymorphisms (SNPs) have been recently discovered associations with PD, but whether they associat
Externí odkaz:
https://doaj.org/article/37051d308e294f6c80e797b32fa19823
Autor:
Simon Haron, Ethan J Kilmister, Paul F Davis, Stanley S Stylli, Theo Mantamadiotis, Andrew H Kaye, Sean R Hall, Swee T Tan, Agadha C Wickremesekera
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 9, Pp 628-642 (2021)
Despite their differences, central nervous system (CNS) tumors and degenerative diseases share important molecular mechanisms underlying their pathologies, due to their common anatomy. Here we review the role of the renin-angiotensin system (RAS) in
Externí odkaz:
https://doaj.org/article/04816149c3aa4ff098288b3e5db93243
Autor:
Kenneth Maiese
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 9, Pp 614-627 (2021)
Introduction: Dementia and cognitive loss impact a significant proportion of the global population and present almost insurmountable challenges for treatment since they stem from multifactorial etiologies. Innovative avenues for treatment are highly
Externí odkaz:
https://doaj.org/article/72736c9e6fdc447591cfb19f1c5d7a89
Autor:
Bipul Ray, Girish Ramesh, Sudhir Rama Verma, Srinivasan Ramamurthy, Sunanda Tuladhar, Arehally Marappa Mahalakshmi, Musthafa Mohamed Essa, Saravana Babu Chidambaram
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 8, Pp 262-271 (2021)
Background: Mitochondrial dysfunction plays a crucial role in Parkinson’s disease (PD) pathogenesis. The present study was undertaken to investigate the effects of Telmisartan (TEL), an angiotensin II type 1 receptor (AT1R) blocker, on the mitochon
Externí odkaz:
https://doaj.org/article/5fc7050063094003bb74fbc39f4bda85
Autor:
James D. Adams
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 26, Iss 8, Pp 387-394 (2021)
Parkinson’s disease, in most patients, is possibly caused by natural oxidative stress in dopaminergic neurons, insufficient exercise and galactose induced oxidative stress. Dopamine oxidizes to produce oxygen radicals that damage neurons. Exercise
Externí odkaz:
https://doaj.org/article/55b58557cff4410c82a9377585eb9a61