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of 36
pro vyhledávání: ''
Autor:
Eva Tvrdá, Michal Ďuračka, Marek Halenár, Juraj Pivko, Eduard Kolesár, Ľubica Chrastinová, Ľubomír Ondruška, Rastislav Jurčík, Adriana Kolesárová
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 6, p 235 (2024)
Background: Apricot kernels containing amygdalin (AMG) as the major cyanogenic glycoside are potentially useful as a complementary therapy for the management of several ailments including cancer. Nevertheless, little is known regarding the toxic and
Externí odkaz:
https://doaj.org/article/423a1c8468f948f999d892fe4270e275
Autor:
Anna S. Tolmacheva, Sergey E. Sedykh, Margarita K. Onvumere, Anna M. Timofeeva, Lada V. Maksimenko, Natalya M. Gashnikova, Georgy A. Nevinsky
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 5, p 191 (2024)
Background: Human immunodeficiency virus (HIV) infection is associated with pronounced oxidative stress, leading to the development of various virus-associated pathologies. A wealth of evidence suggests that, along with canonical enzymes of reactive
Externí odkaz:
https://doaj.org/article/9983a84875634307adaade0f0382594a
Autor:
Neven Žarković, Agnieszka Gęgotek, Wojciech Łuczaj, Morana Jaganjac, Suzana Borović Šunjić, Kamelija Žarković, Elzbieta Skrzydlewska
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 4, p 153 (2024)
Oxidative stress often affects the structure and metabolism of lipids, which in the case of polyunsaturated free fatty acids (PUFAs) leads to a self-catalysed chain reaction of lipid peroxidation (LPO). The LPO of PUFAs leads to the formation of vari
Externí odkaz:
https://doaj.org/article/3e1d8e9059fa4cd68bc4fdffac49f8bb
Autor:
Haihui Xing, Guohua Chen, Faisal Raza, Hajra Zafar, Lei Xing, Qiaoyun Li, Ran Li, Shanshan Xu, Dan Chen
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 3, p 109 (2024)
Background: Severe neurological condition like Alzheimer’s disease (AD) has a significantly negative impact on families and society, wherein there is no proven cure. As one of the principal active constituents of Achyranthes bidentata Blume, ecdyst
Externí odkaz:
https://doaj.org/article/fcee73f351464c23aa3dc2686070af10
Autor:
Lin Liao, Pengyu Tao, Qiming Xu, Wenhao Chen, Jie Chen, Weiwei Liu, Wenrui Liu, Jing Hu, Jianrao Lu
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 58 (2024)
Background: Pyroptosis is a critical form of cell death during the development of chronic kidney disease (CKD). Tripartite motif 6 (TRIM6) is an E3-ubiquitin ligase that participates in the progression renal fibrosis (RF). The aim of this study was t
Externí odkaz:
https://doaj.org/article/bf91b3cdb69c43778dfeb94d27dea47c
Autor:
Filomena Mottola, Sara Ragucci, Maria Carannante, Nicola Landi, Rosaria Scudiero, Antimo Di Maro, Lucia Rocco
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 2, p 51 (2024)
Background: Ribosome inactivating proteins (RIPs) are N-glycosylases found in various plants that are able to specifically and irreversibly inhibit protein translation, thereby leading to cell death. Their cytotoxic properties have attracted attentio
Externí odkaz:
https://doaj.org/article/866178f0df12471795d0c6946a5e38e3
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 29, Iss 1, p 33 (2024)
Objective: Emerging evidence suggests the biological implications of N6-methyladenosine (m6A) in carcinogenesis. Herein, we systematically analyzed the role of m6A modification in renal cell carcinoma (RCC) progression. Methods: Based on 23 m6A regul
Externí odkaz:
https://doaj.org/article/fe3e8d3a5fea409a95bebba49ac27d60
Publikováno v:
Frontiers in Bioscience-Scholar, Vol 15, Iss 4, p 14 (2023)
Background: Diarrhea is the increase in the excretion of human water; meanwhile, fisetin, a bioactive flavonol molecule, is widely used in the treatment/prevention of gastrointestinal disorders. The purpose of this study is to investigate the anti-di
Externí odkaz:
https://doaj.org/article/b62a99a2dfda4dd3ac8e606eccec8454
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 11, p 286 (2023)
Oxidative stress (OS) is linked to hepatocellular carcinoma (HCC) progression. HCC may develop as a result of genetic changes, including oxidative injury to both nuclear and mitochondrial DNA. Signaling pathways regulated by OS, such as Wnt/β-cateni
Externí odkaz:
https://doaj.org/article/2522bc0595ea449db8a1a11ffd2c1a21
Autor:
Minzhuo Liu, Shuiqing Wu, Yi Wu, Jie Zhang, Jun Chen, Xucong Peng, Qiusheng Yang, Zhoujin Tan, Zhihong Zeng
Publikováno v:
Frontiers in Bioscience-Landmark, Vol 28, Iss 11, p 279 (2023)
Background: Age-related macular degeneration (AMD) is the most common cause of visual disorders in the aged population and is characterized by the formation of retinal pigment epithelium (RPE) deposits and dysfunction/death of the RPE and photorecept
Externí odkaz:
https://doaj.org/article/60213d2b227f422dbafb6dfb10c82633