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Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-21 (2024)
Abstract Background Paraptosis is a programmed cell death characterized by cytoplasmic vacuolation, which has been explored as an alternative method for cancer treatment and is associated with cancer resistance. However, the mechanisms underlying the
Externí odkaz:
https://doaj.org/article/dcc7e46d203d44c4b08ea7f9851b1c08
Publikováno v:
Cell & Bioscience, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Autophagy is a cellular self-degradation process that plays a crucial role in maintaining metabolic functions in cells and organisms. Dysfunctional autophagy has been linked to various diseases, including cancer. In cancer, dysregulated auto
Externí odkaz:
https://doaj.org/article/dbd4ff7ddede4c5f856e156e14789e11
Autor:
Ensieh M. Poursani, Daniele Mercatelli, Prahlad Raninga, Jessica L. Bell, Federica Saletta, Felix V. Kohane, Daniel P. Neumann, Ye Zheng, Jourdin R. C. Rouaen, Toni Rose Jue, Filip T. Michniewicz, Piper Schadel, Erin Kasiou, Maria Tsoli, Giuseppe Cirillo, Shafagh Waters, Tyler Shai-Hee, Riccardo Cazzoli, Merryn Brettle, Iveta Slapetova, Maria Kasherman, Renee Whan, Fernando Souza-Fonseca-Guimaraes, Linda Vahdat, David Ziegler, John G. Lock, Federico M. Giorgi, KumKum Khanna, Orazio Vittorio
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-19 (2023)
Abstract Background Metastatic cancer cells exploit Epithelial-mesenchymal-transition (EMT) to enhance their migration, invasion, and resistance to treatments. Recent studies highlight that elevated levels of copper are implicated in cancer progressi
Externí odkaz:
https://doaj.org/article/b17391f9a29d4891bcdc6914896812f8
Autor:
Tania B. López-Méndez, Miguel Sánchez-Álvarez, Flavia Trionfetti, José L. Pedraz, Marco Tripodi, Marco Cordani, Raffaele Strippoli, Juan González-Valdivieso
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-17 (2023)
Abstract In recent years, progress in nanotechnology provided new tools to treat cancer more effectively. Advances in biomaterials tailored for drug delivery have the potential to overcome the limited selectivity and side effects frequently associate
Externí odkaz:
https://doaj.org/article/3b5abf2ef9cc46b3a169a546da1252a6
Publikováno v:
Cell & Bioscience, Vol 13, Iss 1, Pp 1-18 (2023)
Abstract The tetraspanins (TSPANs) are a family of four-transmembrane proteins with 33 members in mammals. They are variably expressed on the cell surface, various intracellular organelles and vesicles in nearly all cell types. Different from the maj
Externí odkaz:
https://doaj.org/article/f34e1e3776f04b53a3983422c89ff92e
Autor:
Liang Zhao, Huizhao Su, Xiaomeng Liu, Hongquan Wang, Yukuan Feng, Yan Wang, Haiqiang Chen, Luo Dai, Shihui Lai, Siqi Xu, Chong Li, Jihui Hao, Bo Tang
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract Background Exploiting cancer metabolism during nutrient availability holds immense potential for the clinical and therapeutic benefits of hepatocellular carcinoma (HCC) patients. Dietary methionine is a metabolic dependence of cancer develop
Externí odkaz:
https://doaj.org/article/4ca65426cb19414cb3d06183ae93c4b7
Autor:
Thomas Fischer, Oliver Hartmann, Michaela Reissland, Cristian Prieto-Garcia, Kevin Klann, Nikolett Pahor, Christina Schülein-Völk, Apoorva Baluapuri, Bülent Polat, Arya Abazari, Elena Gerhard-Hartmann, Hans-Georg Kopp, Frank Essmann, Mathias Rosenfeldt, Christian Münch, Michael Flentje, Markus E. Diefenbacher
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-22 (2022)
Abstract Background Despite advances in treatment of patients with non-small cell lung cancer, carriers of certain genetic alterations are prone to failure. One such factor frequently mutated, is the tumor suppressor PTEN. These tumors are supposed t
Externí odkaz:
https://doaj.org/article/6e2b77747e884b2d9b01fa05018ce46e
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-19 (2022)
Abstract In nature, cells reside in tissues subject to complex cell–cell interactions, signals from extracellular molecules and niche soluble and mechanical signaling. These microenvironment interactions are responsible for cellular phenotypes and
Externí odkaz:
https://doaj.org/article/f412dfa903d34b1691eeb1c3efc4c2a9
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-23 (2022)
Abstract The mitochondrial unfolded protein response (UPRmt) is an evolutionarily conserved protective transcriptional response that maintains mitochondrial proteostasis by inducing the expression of mitochondrial chaperones and proteases in response
Externí odkaz:
https://doaj.org/article/bf41d277c2a846a3a4e5233ef4abed71
Autor:
Raheleh Heydari, Zohreh Jangravi, Samaneh Maleknia, Mehrshad Seresht-Ahmadi, Zahra Bahari, Ghasem Hosseini Salekdeh, Anna Meyfour
Publikováno v:
Cell & Bioscience, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Although sex hormones play a key role in sex differences in susceptibility, severity, outcomes, and response to therapy of different diseases, sex chromosomes are also increasingly recognized as an important factor. Studies demonstrated that
Externí odkaz:
https://doaj.org/article/a25955c447a04af495801d059f3ed5ae