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Publikováno v:
Chinese Medical Journal, Vol 131, Iss 10, Pp 1185-1190 (2018)
Background: Recent studies have indicated that autophagy is involved in sepsis-induced myocardial dysfunction. This study aimed to investigate the change of autophagy in cecal ligation and puncture (CLP)-induced myocardium dysfunction and its relatio
Externí odkaz:
https://doaj.org/article/1ef1f1cdf5424fd18fc0bb4df7aa8de5
Publikováno v:
Chinese Medical Journal, Vol 131, Iss 10, Pp 1158-1166 (2018)
Background: Measurement of general microcirculation remains difficult in septic shock patients. The peripheral perfusion index (PI) and sublingual microcirculation monitoring are thought to be possible methods. This study was performed to determine w
Externí odkaz:
https://doaj.org/article/af3552cc37d540878e6778cfe4889e27
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 10, Pp 1218-1225 (2017)
Background: Leakage of the intestinal mucosal barrier may cause translocation of bacteria, then leading to multiorgan failure. This study hypothesized that rhubarb monomers might protect the gut mucosal barrier in sepsis through junction proteins. Me
Externí odkaz:
https://doaj.org/article/5be71d14b6e24170ac95fb435856c315
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 10, Pp 1146-1154 (2017)
Background: Shock is a life-threatening condition in emergency departments (EDs) and is associated with a high mortality; however, its clinical characteristics and current interventions in China are seldom reported. This study investigated the clinic
Externí odkaz:
https://doaj.org/article/3e8c7cc922e54ae0b1e146e61f9e2cb7
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 10, Pp 1249-1252 (2017)
Externí odkaz:
https://doaj.org/article/8593715457824c3a907a67759087f914
Autor:
Qiang Liu, Chun-Sheng Li
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 8, Pp 986-992 (2017)
Objective: Sepsis remains a leading cause of death in many Intensive Care Units worldwide. Immunosuppression has been a primary focus of sepsis research as a key pathophysiological mechanism. Given the important role of the negative costimulatory mol
Externí odkaz:
https://doaj.org/article/9d68d6d17f3f4fd3b7ec9959df9b773c
Autor:
Yi Huang, Xiao-Xia Wang, Dong-Dong Sun, Ze-Xin Zhang, Wan-Wan Yang, Tian Shao, Han Han, Er-Fei Zhang, Zhong-Shu Pu, Zuo-Xu Hou, Hai-Long Dong, Li-Ze Xiong, Li-Chao Hou
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 7, Pp 840-853 (2017)
Background: Sepsis is a major cause of mortality in Intensive Care Units. Anesthetic dose isoflurane and 100% oxygen were proved to be beneficial in sepsis; however, their application in septic patients is limited because long-term hyperoxia may indu
Externí odkaz:
https://doaj.org/article/77f53972ede346c49137c18353418fec
Publikováno v:
Chinese Medical Journal, Vol 130, Iss 14, Pp 1694-1699 (2017)
Background: Acute kidney injury (AKI) is a severe disease in critically ill patients. Neutrophil infiltration into kidney was associated with the development of AKI, and P-selectin may be involved in the process of neutrophil recruitment in kidney. T
Externí odkaz:
https://doaj.org/article/c443bbe304e0437b985729da581d50d3
Publikováno v:
Chinese Medical Journal, Vol 129, Iss 14, Pp 1725-1730 (2016)
Background: Acute lung injury (ALI) is a common complication of sepsis that is associated with high mortality. Intracellular Ca2+ overload plays an important role in the pathophysiology of sepsis-induced ALI, and cyclic adenosine diphosphate ribose (
Externí odkaz:
https://doaj.org/article/3ae1d65e2d374e12b12bed932f95f714