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Autor:
Gregory S. Cohen, BA, Alison J. Gareau, PhD, Melissa A. Kallarakal, BA, Tayyiaba Farooq, MS, Maria P. Bettinotti, PhD, H. Cliff Sullivan, MD, Abeer Madbouly, PhD, Scott M. Krummey, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1639 (2024)
Background. Biomarkers that predict posttransplant alloimmunity could lead to improved long-term graft survival. Evaluation of the number of mismatched epitopes between donor and recipient HLA proteins, termed molecular mismatch analysis, has emerged
Externí odkaz:
https://doaj.org/article/06be5445608f46b094070a3259a6bc30
Autor:
Chia-Yu Chiu, MD, Maryam Mahmood, MD, Lisa M. Brumble, MD, Holenarasipur R. Vikram, MD, Elitza S. Theel, PhD, Elena Beam, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1672 (2024)
Background. Solid organ transplant (SOT) candidates should be screened and treated for latent tuberculosis infection (LTBI) to prevent tuberculosis (TB) reactivation after transplantation. We aimed to assess the steps from positive QuantiFERON (QFT)
Externí odkaz:
https://doaj.org/article/0f89eaa0ceb241d0856ea4d03277ffd0
Autor:
Antoine Buemi, MD, Nizar I. Mourad, PhD, Caroline Bouzin, PhD, Arnaud Devresse, MD, PhD, Delphine Hoton, MD, Aurelie Daumerie, Francis Zech, MD, PhD, Tom Darius, MD, PhD, Nada Kanaan, MD, Pierre Gianello, MD, PhD, Michel Mourad, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1654 (2024)
Background. In islet transplantation, the use of dynamic hypothermic preservation techniques is a current challenge. This study compares the efficacy of 3 pancreas preservation methods: static cold storage, hypothermic machine perfusion (HMP), and ox
Externí odkaz:
https://doaj.org/article/186452f9e600463493d5039d250f26b0
Autor:
Jørn Petter Lindahl, MD, PhD, Anders Åsberg, MD, PhD, Kristian Heldal, MD, PhD, Trond Jenssen, MD, PhD, Christina Dörje, MD, PhD, Morten Skauby, MD, Karsten Midtvedt, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1660 (2024)
Background. Transplantation of kidneys from elderly donations after brain death (DBD) donors has increased owing to organ shortages. We aimed to assess the impact on long-term kidney transplant outcomes from DBD donors aged 70 y and older compared wi
Externí odkaz:
https://doaj.org/article/1769bc3fe0a54977a19a459b95a5b505
Autor:
Jacob Saks, DO, Uzung Yoon, MD, MPH, Natalie Neiswinter, MD, Eric S. Schwenk, MD, Stephen Goldberg, MD, Linh Nguyen, MD, Marc C. Torjman, PhD, Elia Elia, MD, Ashesh Shah, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1663 (2024)
Background:. Enhanced recovery after surgery (ERAS) pathways represent a comprehensive approach to optimizing perioperative management and reducing hospital stay and cost. In living donor kidney transplantation, key impediments to postoperative disch
Externí odkaz:
https://doaj.org/article/12652214f3d746a196b664dfa0a1b85a
Autor:
Georgina L. Irish, MMed (ClinEpi), Riadh A.S. Fadhil, MD, Eric Rondeau, PhD, Sanjay Nagral, MD, Mohammadali Ahmadipour, MASc, P. Toby Coates, PhD, Dominique E. Martin, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1655 (2024)
Background. Lack of data regarding international travel for organ transplantation (ITOT) hampers efforts to evaluate, understand, and respond to trends in ITOT activities, such as those suggestive of organ trafficking or “transplant tourism.” Thi
Externí odkaz:
https://doaj.org/article/1890f110c2994359a760ec82e1a6426d
Autor:
Chikako Endo, MD, Bianca Lascaris, MD, Isabel M. A. Brüggenwirth, MD, PhD, Jan Roggeveld, MBO, Hans Blokzijl, MD, PhD, Vincent E. de Meijer, MD, PhD, M. H. Edwina Doting, MD, PhD, Robert J. Porte, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1664 (2024)
Background. Ex situ machine perfusion is increasingly used to preserve and assess donor livers before transplantation. Compared with traditional static cold storage (SCS), machine perfusion exposes livers to an additional risk of microbial contaminat
Externí odkaz:
https://doaj.org/article/26bc4ba3f3d242178b8ecb904c6ef577
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1657 (2024)
Background. The role of donor age in liver transplantation (LT) outcomes for hepatocellular carcinoma (HCC) is controversial. Given the significant risk of HCC recurrence post-LT, optimizing donor/recipient matching is crucial. This study reassesses
Externí odkaz:
https://doaj.org/article/290a1cb0f08f45e4b8185d5a4b594c96
Autor:
Aleksandar Denic, MD, PhD, Alessia Buglioni, MD, Sandor Turkevi-Nagy, MD, Mateo Velasquez Mejia, MD, Byron H. Smith, PhD, Walter D. Park, BS, Rashmi Subramani, MBBS, Aleksandra Kukla, MD, Tayyab S. Diwan, MD, Joseph P. Grande, MD, Mark D. Stegall, MD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1652 (2024)
Background. Mesangial expansion (ME) is an understudied histologic lesion in renal allografts. The current Banff mm score is not reproducible and may miss important ME features. The study aimed to improve the quantification of ME using morphometry, a
Externí odkaz:
https://doaj.org/article/45bce354c7064644a3bb209d0d7bc610
Autor:
Aixia Sun, MD, PhD, Hanaan Hayat, BS, Elizabeth Kenyon, MS, Tahnia Quadri, BS, Darius Amos, BS, Keenan Perkins, BS, Saumya Nigam, PhD, Deanna Tarleton, BS, Christiane L. Mallett, PhD, Cheri X. Deng, PhD, Zhen Qiu, PhD, Wen Li, PhD, Lorenzo Sempere, PhD, Jinda Fan, PhD, Aitor Aguirre, PhD, Ping Wang, MD, PhD
Publikováno v:
Transplantation Direct, Vol 10, Iss 7, p e1658 (2024)
Background. Transplantation of human-induced pluripotent stem cell (hiPSC)-derived islet organoids is a promising cell replacement therapy for type 1 diabetes (T1D). It is important to improve the efficacy of islet organoids transplantation by identi
Externí odkaz:
https://doaj.org/article/3f037444dfe7407295fe2c837d727b56