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Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 3, Pp 46-57 (2020)
The interaction of the fifth kringle of Glu-plasminogen with fibrin triggers activation and initiation of fibrinolysis, yet the site on fibrin that binds kringle 5 remains unknown. The aim of our work was to determine an amino acid sequence in the D-
Externí odkaz:
https://doaj.org/article/879e8ae2101248918bd7d6cb4eae8ba5
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 1, Pp 31-40 (2020)
Platelets store, produce and release a variety of angiogenesis regulators, which can contribute to both normal tissue repair and angiopathy-associated pathologies. Plasminogen has been earlier shown to regulate some platelet functions, but if it is a
Externí odkaz:
https://doaj.org/article/fd349aa18c6e4f93a9e5b409b2a7f720
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 6, Pp 38-48 (2019)
Platelets play a key role in hemostasis as cofactors of thrombin generation, fibrin polymerization centers, and initiators of clot retraction, while their ability to modulate clot dissolution remains less understood. The aim of this study was to in
Externí odkaz:
https://doaj.org/article/6e534a9f23264e34bd3f57e8645ace11
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 6, Pp 31-40 (2018)
Reactive oxygen species (ROS) are considered to be important signalling molecules controlling many platelet functions. ROS production has been shown to be augmented by platelet activation, however, plasminogen (Pg) has not been studied in the context
Externí odkaz:
https://doaj.org/article/50aabc5305584f07a9ccda8cd5a466ab
Publikováno v:
The Ukrainian Biochemical Journal, Vol 89, Iss 5, Pp 21-31 (2017)
In the present study, we investigated whether calcium content modulation in D-domains of fibrin(ogen) was involved in fibrinolytic process activation. To investigate the effect of Ca2+-dependent changes in D-domains two types of fibrinogen fragments
Externí odkaz:
https://doaj.org/article/7336a3bbc5f5490dba5ce832132bd4c4
Publikováno v:
The Ukrainian Biochemical Journal, Vol 87, Iss 5, Pp 103-112 (2015)
It is known that benign breast tissue exhibit relatively low angiogenic capacity. Activation of angiogenesis in mammary pre-malignant lesions could be associated with disease progression and high risk of transformation into the breast cancer. However
Externí odkaz:
https://doaj.org/article/5699b353f80d4f2eb10407ec62aca9c0
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 6, Pp 94-105 (2013)
Current knowledge of the mechanisms of blood coagulation does not provide an answer to one pivotal question: why is, in contrast to a pathological thrombus, the growth of normal hemostatic clot after blood vessel injury suddenly terminated? In the pr
Externí odkaz:
https://doaj.org/article/3396b2a491484ee9a502bb6654558f21
Autor:
R. P. Vynogradova, V. M. Danilova
Publikováno v:
The Ukrainian Biochemical Journal, Vol 85, Iss 2, Pp 110-118 (2013)
The article presents the information about the life and scientific activity of the Palladin Prize laureats. In 1985, S. O. Kudinov was awarded the Prize for his monograph ”Ca2+ transport systems in nerve cells”. In 1986, A. Ya. Rozanov, A. I. Tre
Externí odkaz:
https://doaj.org/article/95a5164d2aa645e69d9f760931aa3985