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pro vyhledávání: ''
Publikováno v:
The Ukrainian Biochemical Journal, Vol 96, Iss 1, Pp 73-79 (2024)
Diethyl phthalate (DEF) is a synthetic chemical widely used as plasticizer and additive in personal care and pharmaceutical products. Low-dose exposure to this xenobiotic over a long period contributes to its intake into the human body in a high dose
Externí odkaz:
https://doaj.org/article/142d4c02cc6d43f6909bcf43a1b2d0a1
Publikováno v:
The Ukrainian Biochemical Journal, Vol 95, Iss 6, Pp 64-72 (2023)
Colorectal cancer is one of the leading causes of mortality in the world. The search for new methods of therapy for this disease that could correct the state of oxidative stress during the development of neoplasms is up to date. The aim of this work
Externí odkaz:
https://doaj.org/article/cf278da27a0e48e4be860d49ef62cf5d
Publikováno v:
The Ukrainian Biochemical Journal, Vol 95, Iss 5, Pp 51-60 (2023)
An unhealthy diet often is a cause of obesity, chronic inflammation, and metabolic disruption in multiple organs. However, the direct influence of elevated lipid or sugar consumption on liver, pancreatic, and sperm mitochondria is not well understood
Externí odkaz:
https://doaj.org/article/96223dfb6d4e46b996056e54b8894463
Publikováno v:
The Ukrainian Biochemical Journal, Vol 93, Iss 3, Pp 61-67 (2021)
Thiazole derivatives were shown to have toxic effects in vitro on cancer cells of different origin and can be considered as potentially antineoplastic, but their effect on the normal tissues needs to be studied. In this research the newly synthesized
Externí odkaz:
https://doaj.org/article/70ac6bb362184dab867c6878c0bcdb10
Autor:
B. І. Kotyk, R. Ya. Iskra, O. M. Slivinska, N. M. Liubas, A. Z. Pylypets, V. I. Lubenets, V. I. Pryimych
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 5, Pp 78-86 (2020)
Ethylthiosulfanylate is alkyl ester of thiosulfoacid and belongs to the class of thiosulfonate compounds. Structurally, thiosulfonates are synthetic analogues of natural phytoncides. It is known that, natural organic sulfur-containing compounds are c
Externí odkaz:
https://doaj.org/article/2279ca9591a741d186f528bbdbdcee58
Autor:
D. O. Labudzynskyi, I. O. Shymanskyi, O. O. Lisakovska, A. O. Mazanova, L. V. Natrus, M. M. Veliky
Publikováno v:
The Ukrainian Biochemical Journal, Vol 92, Iss 4, Pp 5-13 (2020)
The deficiency of vitamin D is associated with the risk of various chronic diseases, including diabetes mellitus and its complications. Given the strong genomic action of vitamin D hormone-active form, its deficiency can lead to dysfunction of cytoki
Externí odkaz:
https://doaj.org/article/7fa2cbedc842455a8624771e5a37ab5f
Autor:
T. V. Vovkun, P. I. Yanchuk, L. Ya. Shtanova, S. P. Veselsky, N. B. Filimonova, I. V. Komarov
Publikováno v:
The Ukrainian Biochemical Journal, Vol 91, Iss 6, Pp 112-121 (2019)
Quercetin (QUE) and its water-soluble form сorvitin are medicinally important members of the flavonoid family and the most prominent dietary antioxidants. Numerous pharmacological effects of quercetin include protection against diseases, such as a
Externí odkaz:
https://doaj.org/article/5c7018b93e1f474ab307c00a86bee395
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 6, Pp 120-125 (2018)
The effect of octadecylamide of alginic acid on blood serum and hepatic cholesterol, and the faecal output of fat and sterols was examined in female rats fed diets containing cholesterol and palm fat at 10 and 50 g/kg, respectively for 10 weeks. Amid
Externí odkaz:
https://doaj.org/article/58f627257ca24f6d90013c6abc743c71
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 4, Pp 36-44 (2018)
The study was performed to investigate the effects of the separate and combined action of omega-3 polyunsaturated fatty acids (ω-3 PUFAs) and vitamin D3 on the activity of the components of the oxygenase and reductase chains of the monooxygenase sys
Externí odkaz:
https://doaj.org/article/144fc6b87b424164980e93784e99a475
Autor:
L. G. Babich, S. G. Shlykov, A. M. Kushnarova-Vakal, N. I. Kupynyak, V. V. Manko, V. P. Fomin, S. O. Kosterin
Publikováno v:
The Ukrainian Biochemical Journal, Vol 90, Iss 3, Pp 32-40 (2018)
The aim of the study was to show the relationships between ionized Ca concentration ([Ca2+]m) in the mitochondria matrix and functional activity of this organelle. [Ca2+]m was determined using the fluorescent probe Fluo-4, AM. Total level of Ca2+ acc
Externí odkaz:
https://doaj.org/article/8add5031a8ed482a86eef510a46eb27a