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of 30
pro vyhledávání: ''
Autor:
Hesamoddin Arabnozari, Fatemeh Shaki, Abolfazl Najjari, Fariborz Sharifianjazi, Satyajit D. Sarker, Emran Habibi, Lutfun Nahar
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract Diabetic nephropathy, characterized by inflammation and oxidative stress, poses a management challenge. This study investigates the effect of Polygonum hyrcanicum extract on diabetic nephropathy in alloxan-induced diabetic mice. In this expe
Externí odkaz:
https://doaj.org/article/8b8ff270b6cb46a78df4fc4a578ac648
Autor:
Abdul Samad, Sammia Shahid, Sana Mansoor, Sehrish Afzal, Mohsin Javed, Ammar Zidan, Abdullah Shoaib, Fadi Jaber, Shahid Iqbal, Muhammad Saad, Sajid Mahmood, Nasser S. Awwad, Hala A. Ibrahium
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract Diabetes mellitus (DM) is a rapidly prevailing disease throughout the world that poses boundless risk factors linked to several health problems. Vildagliptin is the standard dipeptidyl peptidase-4 (DPP-4) inhibitor type of medication that is
Externí odkaz:
https://doaj.org/article/d76409734d4d46dc9ce2d64bc3fcf3aa
Autor:
Mahmoud M. Gabr, Sawsan M. El-Halawani, Ayman F. Refaie, Sherry M. Khater, Amani M. Ismail, Mary S. Karras, Raghda W. Magar, Shorouk El Sayed, Malgorzata Kloc, Ahmed Uosef, Omaima M. Sabek, Mohamed A. Ghoneim
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-15 (2024)
Abstract This study was to determine whether extracellular vesicles (EVs) derived from insulin-producing cells (IPCs) can modulate naïve mesenchymal stromal cells (MSCs) to become insulin-secreting. MSCs were isolated from human adipose tissue. The
Externí odkaz:
https://doaj.org/article/c763a3cff9ee422abf116a22f6795d92
Autor:
Xu Jia, Danting Mao, Jianwei Guo, Jiangyu Ke, Yanlin Zhu, Xiaoyang Zhao, Ziren Luo, Xinghai Liu, Rui Tang, Ruihan Hou, Haitao Lan, Qian zheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Long-term exposure to hyperglycemic conditions leads to β-cell dysfunction, particularly mitochondrial dysfunction, and inflammatory and oxidative stress responses, which are considered the primary causes of β-cell death and the hallmarks
Externí odkaz:
https://doaj.org/article/0a7e093681f9453e8c355ffd13e3da01
Autor:
Tatsunori Satoh, Eiji Nakatani, Hiroyuki Ariyasu, Shinya Kawaguchi, Kazuya Ohno, Hiroshi Itoh, Kaori Hayashi, Takeshi Usui
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Pancreatic cancer presents a critical health issue characterized by low survival rates. Identifying risk factors in specific populations, such as those with diabetes, is crucial for early detection and improved outcomes. This study aimed to
Externí odkaz:
https://doaj.org/article/598164a76d5d480eb48e198fa40126c8
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract NSG mice are among the most immunodeficient mouse model being used in various scientific branches. In diabetelogical research diabetic NSG mice are an important asset as a xenotransplantation model for human pancreatic islets or pluripotent
Externí odkaz:
https://doaj.org/article/6256d8f998264250a72bfefb1458a63b
Autor:
Muhammad Farman, Ali Akgül, Muhammad Sultan, Sidra Riaz, Hira Asif, Praveen Agarwal, Murad Khan Hassani
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-19 (2024)
Abstract COVID-19 is linked to diabetes, increasing the likelihood and severity of outcomes due to hyperglycemia, immune system impairment, vascular problems, and comorbidities like hypertension, obesity, and cardiovascular disease, which can lead to
Externí odkaz:
https://doaj.org/article/f5e6fcf68f4141c7afec826ef58f28d1
Autor:
Alhussain H. Aodah, Faisal K. Alkholifi, Khalid M. Alharthy, Sushma Devi, Ahmed I. Foudah, Hasan S. Yusufoglu, Aftab Alam
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Diabetes mellitus (DM) is a chronic metabolic disorder characterized by persistent hyperglycemia. It involves disturbances in carbohydrate, fat, and protein metabolism due to defects in insulin secretion, insulin action, or both. Novel thera
Externí odkaz:
https://doaj.org/article/d831686d361b476389fe670ea8b3c5d5
Autor:
Junxi Liu, Rebecca C. Richmond, Emma L. Anderson, Jack Bowden, Ciarrah-Jane S. Barry, Hassan S. Dashti, Iyas S. Daghlas, Jacqueline M. Lane, Simon D. Kyle, Céline Vetter, Claire L. Morrison, Samuel E. Jones, Andrew R. Wood, Timothy M. Frayling, Alison K. Wright, Matthew J. Carr, Simon G. Anderson, Richard A. Emsley, David W. Ray, Michael N. Weedon, Richa Saxena, Martin K. Rutter, Deborah A. Lawlor
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-14 (2024)
Abstract Self-reported shorter/longer sleep duration, insomnia, and evening preference are associated with hyperglycaemia in observational analyses, with similar observations in small studies using accelerometer-derived sleep traits. Mendelian random
Externí odkaz:
https://doaj.org/article/7570bd5e2c7049fda1219de8ef4b9840
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-11 (2024)
Abstract The triglyceride glucose body mass index (TyG-BMI) is a potential indicator for insulin resistance, but its association with mortality in diabetic patients is unclear. This study investigates the relationship between TyG-BMI and all-cause an
Externí odkaz:
https://doaj.org/article/113aeae080e14f64bbe1eb3954beafc7