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Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-16 (2024)
Abstract Lung adenocarcinoma is the most common primary lung cancer seen in the world, and identifying genetic markers is essential for predicting the prognosis of lung adenocarcinoma and improving treatment outcomes. It is well known that alteration
Externí odkaz:
https://doaj.org/article/8b2400a27c364ddabb1ff936e87475cd
Autor:
Min Chen, Yingdi Meng, Xiaoqiong Shi, Chengjing Zhu, Minhui Zhu, Haihong Tang, Hongliang Zheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Several studies reveal that allergic rhinitis (AR) is a significant risk factor of systemic lupus erythematosus (SLE). However, studies investigating the common pathogenesis linking AR and SLE are lacking. Our study aims to search for the sh
Externí odkaz:
https://doaj.org/article/e7439e3118e74299b8e0aa59b7243d61
Autor:
Shiyao Zheng, Hongxin He, Jianfeng Zheng, Xingshu Zhu, Nan Lin, Qing Wu, Enhao Wei, Caiming Weng, Shuqian Chen, Xinxiang Huang, Chenxing Jian, Shen Guan, Chunkang Yang
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-17 (2024)
Abstract Colorectal liver metastasis (CRLM) is challenging in the clinical treatment of colorectal cancer. Limited research has been conducted on how CRLM develops. RNA sequencing data were obtained from the Gene Expression Omnibus (GEO) and The Canc
Externí odkaz:
https://doaj.org/article/e6834454f28c491da873dcb30b9fe06f
Autor:
Elijah Kolawole Oladipo, Taiwo Ooreoluwa Ojo, Oluwabamise Emmanuel Elegbeleye, Olawale Quadri Bolaji, Moyosoluwa Precious Oyewole, Abdeen Tunde Ogunlana, Emmanuel Obanijesu Olalekan, Bamidele Abiodun, Daniel Adewole Adediran, Oluwaseun Adeola Obideyi, Seun Elijah Olufemi, Ahmad Mohammad Salamatullah, Mohammed Bourhia, Youssouf Ali Younous, Temitope Isaac Adelusi
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-22 (2024)
Abstract The available Epstein Barr virus vaccine has tirelessly harnessed the gp350 glycoprotein as its target epitope, but the result has not been preventive. Right here, we designed a global multi-epitope vaccine for EBV; with special attention to
Externí odkaz:
https://doaj.org/article/e69e8844719e444b8aaea99542bf6c94
Autor:
Jue Gu, Yamin Zhao, Yue Ben, Siming Zhang, Liqi Hua, Songnian He, Ruizi Liu, Xu Chen, Hongzhuan Sheng
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Hypertrophic cardiomyopathy (HCM) may lead to cardiac dysfunction and sudden death. This study was designed to develop a HCM signature applying bioinformatics and machine learning methods. Data of HCM and normal tissues were obtained from pu
Externí odkaz:
https://doaj.org/article/3df3ba0001404acba329bcea99b99b04
Autor:
Xize Wu, Changbin Yuan, Jiaxiang Pan, Yi Zhou, Xue Pan, Jian Kang, Lihong Ren, Lihong Gong, Yue Li
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-20 (2024)
Abstract Non-alcoholic steatohepatitis (NASH) is a hepatocyte inflammation based on hepatocellular steatosis, yet there is no effective drug treatment. Atherosclerosis (AS) is caused by lipid deposition in the endothelium, which can lead to various c
Externí odkaz:
https://doaj.org/article/5a353953552143cda6b3faba0c2a6bee
Autor:
Cléo Maia Cordeiro, Gislenne da Silva Moia, Mônica Silva de Oliveira, Lucas da Silva e Silva, Maria Paula da Cruz Schneider, Sávio S. Costa, Rafael Azevedo Baraúna, Diego Assis das Graças, Artur Silva, Adonney Allan de Oliveira Veras
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-8 (2024)
Abstract Bioinformatics tools are essential for performing analyses in the omics sciences. Given the numerous experimental opportunities arising from advances in the field of omics and easier access to high-throughput sequencing platforms, these tool
Externí odkaz:
https://doaj.org/article/a5e9c9bdb2ef4c8ba6a1dc4b5e8c661a
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-18 (2024)
Abstract Premature ovarian failure (POF), which is often comorbid with dry eye disease (DED) is a key issue affecting female health. Here, we explored the mechanism underlying comorbid POF and DED to further elucidate disease mechanisms and improve t
Externí odkaz:
https://doaj.org/article/04c2d00452c34768837c7cc5132e7a2d
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-12 (2024)
Abstract Binding of Staphylococcus aureus protein A (SPA) to osteoblasts induces apoptosis and inhibits bone formation. Bone marrow-derived mesenchymal stem cells (BMSCs) have the ability to differentiate into bone, fat and cartilage. Therefore, it w
Externí odkaz:
https://doaj.org/article/5beedcf9ebb84a458902eb2cf633bd03
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-9 (2024)
Abstract Lebanon’s rich history as a cultural crossroad spanning millennia has significantly impacted the genetic composition of its population through successive waves of migration and conquests from surrounding regions. Within modern-day Lebanon,
Externí odkaz:
https://doaj.org/article/7b06d525fe194941939d29305475e2f3