Zobrazeno 1 - 10
of 161
pro vyhledávání: '"59"'
Autor:
Weiping Ji, Jiquan Shen, Bo Wang, Feifei Chen, Deru Meng, Shuanghu Wang, Dapeng Dai, Yunfang Zhou, Changxiong Wang, Quan Zhou
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 457-464 (2021)
Context Dacomitinib and poziotinib, irreversible ErbB family blockers, are often used for treatment of non-small cell lung cancer (NSCLC) in the clinic. Objective This study investigates the effect of dacomitinib on the pharmacokinetics of poziotinib
Externí odkaz:
https://doaj.org/article/af63f29ece98421284ff54271032982c
Autor:
Zhong-Ping Gou, Yun-Li Zhao, Lin-Ling Zou, Ying Wang, Shi-Qing Shu, Xiao-Hong Zhu, Li Zheng, Qi Shen, Zhu Luo, Jia Miao, Yong-Sheng Wang, Xiao-Dong Luo, Ping Feng
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 484-493 (2021)
Context Capsule of alkaloids from the leaf of Alstonia scholaris (L.) R.Br. (Apocynaceae) (CALAS) is a new investigational botanical drug (No. 2011L01436) for bronchitis, post-infectious cough and asthma. Objective To observe the clinical safety and
Externí odkaz:
https://doaj.org/article/9218aa37854f4228817074c39fa13559
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 1-10 (2021)
Context Zataria multiflora Boiss (Lamiaceae) essential oil (ZME) is believed to be a bactericide herbal medicine and might alleviate negative effects of infection. Objective This study evaluates the effects of an ointment prepared from ZME (ZMEO) on
Externí odkaz:
https://doaj.org/article/c5f5bbb9fc0543779347a476355de93f
Autor:
Cong Fang, Yahui Liu, Lanying Chen, Yingying Luo, Yaru Cui, Ni Zhang, Peng Liu, Mengjing Zhou, Yongyan Xie
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 11-20 (2021)
Context α-Hederin, a potent bioactive compound of Pulsatilla chinensis (Bunge) Regel (Ranunculaceae), has many pharmacological uses, but its effect on cancer cell metabolism is still unclear. Objective To elucidate the role of α-hederin in the gluc
Externí odkaz:
https://doaj.org/article/f1fe79cbc91d42499f3c43a917b30445
Autor:
Wanyi Ng, Chenyuan Gong, Xuewei Yan, Guifan Si, Chen Fang, Lixin Wang, Xiaowen Zhu, Zihang Xu, Chao Yao, Shiguo Zhu
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 47-53 (2021)
Context Therapeutic benefits of immunotherapy are restricted by cancer immune-resistance mechanisms. Rediocide-A (Red-A), a natural product extracted from Traditional Chinese Medicine, is a promising agent to battle against cancer which acts as an im
Externí odkaz:
https://doaj.org/article/30b2ec7fba0f4e90a91adfcf69a84229
Autor:
Hongyan Ma, Shanshan Liu, Wenshan Qu, Qi Huang, Linyuan Li, Fujiang Chu, Yuyun Zhu, Xinlin Lv, Zhimin Wang, Jingjing Zhu
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 40-46 (2021)
Context The traditional drying method, sun drying, for Chrysanthemum morifolium Ramat. cv. Hang-ju (Compositae) (HJ) is widely replaced by sulphur fumigation (SF), which has an unknown effect on its efficacy. Objective To investigate protective effec
Externí odkaz:
https://doaj.org/article/8623c61932e0420fbd1a84423becf357
Autor:
Ernawati Sinaga, Ami Fitrayadi, Asrori Asrori, Sri Endarti Rahayu, Suprihatin Suprihatin, Vivitri Dewi Prasasty
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 31-39 (2021)
Context Pandanus odoratissimus Linn. (Pandanaceae) seed extract is known to have antioxidant activities. However, the potential hepatoprotective effect is still unclear. Objective To investigate the hepatoprotection aspect of P. odoratissimus methano
Externí odkaz:
https://doaj.org/article/4203423a809d42c799e6a2febafd0af3
Autor:
Nurdiana Samsulrizal, Yong-Meng Goh, Hafandi Ahmad, Sulaiman Md Dom, Nur Syimal’ain Azmi, Noor Syaffinaz NoorMohamad Zin, Mahdi Ebrahimi
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 66-73 (2021)
Context Diabetes mellitus increases the risk of bone diseases including osteoporosis and osteoarthritis. We have previously demonstrated that Ficus deltoidea Jack (Moraceae) is capable of reducing hyperglycaemia. However, whether F. deltoidea could p
Externí odkaz:
https://doaj.org/article/753fd798476e455b88640249944f7fdc
Autor:
Justyna Stefanowicz-Hajduk, Magdalena Gucwa, Barbara Moniuszko-Szajwaj, Anna Stochmal, Anna Kawiak, J. Renata Ochocka
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 54-65 (2021)
Context Bufadienolide compounds occur in many plants and animal species and have strong cardiac and anti-inflammatory properties. The compounds have been recently investigated for cytotoxic and antitumor activity. Objective The cytotoxic effect of be
Externí odkaz:
https://doaj.org/article/902c44e064e34fd981a817492c774fd1
Publikováno v:
Pharmaceutical Biology, Vol 59, Iss 1, Pp 21-30 (2021)
Context Berberine (BBR) is used to treat diarrhoea and gastroenteritis in the clinic. It was found to have anticolon cancer effects. Objective To study the anticolon cancer mechanism of BBR by connectivity map (CMAP) analysis. Materials and methods C
Externí odkaz:
https://doaj.org/article/9e007ff5e24446cba20748bce3b1cc49