Zobrazeno 1 - 10
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pro vyhledávání: ''
Publikováno v:
Heliyon, Vol 6, Iss 11, Pp e05546- (2020)
Alzheimer's disease is a progressive neurodegenerative disorder. In this disease neurodegeneration occurs due to deposition of aggregated amyloid-beta plaques and neurofibrillary tangles (hyperphosphorylated tau proteins). Present study focuses on in
Externí odkaz:
https://doaj.org/article/672271e40fdf40d3992e05c2d7f17d8f
Autor:
Zahra Lorigooini, Shakiba Nasiri boroujeni, Shima Balali-Dehkordi, Leila Ebrahimi, Elham Bijad, Mohammad Rahimi-Madiseh, Hossein Amini-Khoei
Publikováno v:
Heliyon, Vol 6, Iss 9, Pp e04833- (2020)
Background and aim: Anxiety disorders are one of the most common psychiatric disorders worldwide. Common anti-anxiety medications are associated with several side effects. Caffeic acid (CA) is a phenolic compound with several pharmacological effects.
Externí odkaz:
https://doaj.org/article/7a441e3c12d9458eaea67b31dd08c5fb
Publikováno v:
Heliyon, Vol 6, Iss 8, Pp e04774- (2020)
A 78 year-old female presented with dropped head syndrome (DHS). Three months before her initial visit to our hospital, the patient noticed a pronounced flexion of her head and neck with subsequent deterioration of symptoms, which included neck pain,
Externí odkaz:
https://doaj.org/article/b74374a9eece4463b0ba8348a039f2c3
Autor:
Anastasia Levchenko, Timur Nurgaliev, Alexander Kanapin, Anastasia Samsonova, Raul R. Gainetdinov
Publikováno v:
Heliyon, Vol 6, Iss 5, Pp e03990- (2020)
A personalized medicine approach seems to be particularly applicable to psychiatry. Indeed, considering mental illness as deregulation, unique to each patient, of molecular pathways, governing the development and functioning of the brain, seems to be
Externí odkaz:
https://doaj.org/article/1f0610f418004d4fa78a81a20ab2ed0b
Autor:
Tiago Guardia de Souza e Silva, Maria Eliza Ferreira do Val de Paulo, Jeferson Rubens Mamona da Silva, Adilson da Silva Alves, Luiz Roberto G. Britto, Gilberto Fernando Xavier, Maria Regina Lopes Sandoval
Publikováno v:
Heliyon, Vol 6, Iss 2, Pp e03281- (2020)
Alzheimer's disease (AD) is a neurodegenerative disorder characterized by progressive decline in cognitive function. Intracerebroventricular injection of streptozotocin (icv-STZ) has been used as an experimental model of Sporadic AD (SAD) in rodents
Externí odkaz:
https://doaj.org/article/5f1211ee607f458aad1f9c540b3e0dbd
Publikováno v:
Heliyon, Vol 5, Iss 10, Pp e02662- (2019)
Yokukansan (YKS), a traditional Japanese Kampo medicine, affects neurological and psychiatric disorders. It ameliorates hippocampal neurogenesis in animals. However, its effect on neuronal cell differentiation remains unclear. Therefore, we investiga
Externí odkaz:
https://doaj.org/article/c7f75e90d45249a98f9fce74a2ce5d9d
Autor:
H.B. Li
Publikováno v:
Heliyon, Vol 5, Iss 4, Pp e01567- (2019)
Introduction: A considerable part of old people suffer from Chronic Cerebral Hypoperfusion (CCH) in their long lives but have no way to change. The Modified Dioscorea Pills (MDP), a Chinese compound herbal prescription, has good clinical efficacy for
Externí odkaz:
https://doaj.org/article/5b8b3211085c4798a792c8d802e1d89f
Autor:
Josefina Higgs, Cristina Wasowski, Alejandra Marcos, Marko Jukič, Carlos Humberto Paván, Stanislav Gobec, Felicitas de Tezanos Pinto, Natalia Colettis, Mariel Marder
Publikováno v:
Heliyon, Vol 5, Iss 3, Pp e01376- (2019)
Anxiety disorders, depression and pain are highly prevalent pathologies. Their pharmacotherapy is associated with unwanted side effects; hence there is a clinical need to develop more effective drugs with fewer adverse reactions.Chalcones are one of
Externí odkaz:
https://doaj.org/article/b5c10089ecc749e79bd97fd12b3d553d
Publikováno v:
Heliyon, Vol 5, Iss 1, Pp e01190- (2019)
The anti-oxidant effects of melatonin and the immune-pineal axis are well established. However, how they play a role in the pathogenesis of neurodegenerative diseases is not well elucidated. A better understanding of this neuro-immuno-endocrinologica
Externí odkaz:
https://doaj.org/article/6405d0b669224b3dbebc177f401caf18
Autor:
Simona Scheggi, Teresa Pelliccia, Alessandro Cuomo, Maria Graziella De Montis, Carla Gambarana
Publikováno v:
Heliyon, Vol 4, Iss 10, Pp e00849- (2018)
Background: The antiepileptic lamotrigine is approved for maintenance treatment of bipolar disorder and augmentation therapy in treatment-resistant depression. Previous preclinical investigations showed lamotrigine antidepressant-like effects without
Externí odkaz:
https://doaj.org/article/799b9afa1612435ca20731498fd829d9