Zobrazeno 1 - 10
of 10
pro vyhledávání: '"ZHAO LI"'
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/fb34b85e071843058c694c7ddab8086a
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: On 15 June 2020, the United States Food and Drug Administration (FDA) approved lurbinectedin for treating adult patients with metastatic small-cell lung cancer whose disease has progressed despite prior platinum-based chemotherapy. Follow
Externí odkaz:
https://doaj.org/article/9ed3909bd0c94c9cba8d9654496e6a5d
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Acting as a cysteine protease, small ubiquitin-like modifier (SUMO)/sentrin-specific protease1 (SENP1) involved in multiple physiological and pathological processes through processing the precursor SUMO protein into mature form and deSUMOylating targ
Externí odkaz:
https://doaj.org/article/6c546f15df04484f83d42fc1755fc0ea
YKL-40 promotes chemokine expression following drug-induced liver injury via TF-PAR1 pathway in mice
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: The inflammatory factor YKL-40 is associated with various inflammatory diseases and is key to remodeling inflammatory cells and tissues. YKL-40 (Chi3l1) promotes the activation of tissue factor (TF), leading to intrahepatic vascular coagu
Externí odkaz:
https://doaj.org/article/3d14bc9d0485435ca0405b0d27a63b90
Autor:
Tiantian Wang, Chunxia Liu, Ling-hui Pan, Zhen Liu, Chang-long Li, Jin-yuan Lin, Yi He, Jing-yuan Xiao, Siyi Wu, Yi Qin, Zhao Li, Fei Lin
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Background: Lung ischemia reperfusion injury (LIRI) is a complex pathophysiological process activated by lung transplantation and acute lung injury. The p38 mitogen-activated protein kinase (MAPK) is involved in breakdown of the endothelial barrier d
Externí odkaz:
https://doaj.org/article/cb471d851d984abc9b34fe91f829eff3
Autor:
Jing Yang, Rongjun Liu, Fan Lu, Fang Xu, Jinwei Zheng, Zhao Li, Wei Cui, Chuang Wang, Junfang Zhang, Shujun Xu, Wenhua Zhou, Qinwen Wang, Junping Chen, Xiaowei Chen
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Depression is a common neuropsychiatric disorder and new anti-depressive treatments are still in urgent demand. Fast Green FCF, a safe biocompatible color additive, has been suggested to mitigate chronic pain. However, Fast green FCF’s effect on de
Externí odkaz:
https://doaj.org/article/08396b3c9a8d4fb38380dbfa299f798b
Autor:
Tongyue Yang, Qi Feng, Mingwei Shao, Mengxing Pan, Feng Guo, Yi Song, Fengjuan Huang, Zhao Linlin, Jiao Wang, Lina Wu, Guijun Qin, Yanyan Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Diabetic kidney disease (DKD) is characterized by complex pathogenesis and poor prognosis; therefore, an exploration of novel etiological factors may be beneficial. Despite glycemic control, the persistence of transient hyperglycemia still induces va
Externí odkaz:
https://doaj.org/article/7ca61470a6764da0859fd66d9516d88b
Autor:
Yumei Wang, Qing Ai, Meiling Gu, Hong Guan, Wenqin Yang, Meng Zhang, Jialin Mao, Zhao Lin, Qi Liu, Jicheng Liu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Morus alba L., a common traditional Chinese medicine (TCM) with a centuries-old medicinal history, owned various medicinal parts like Mori folium, Mori ramulus, Mori cortex and Mori fructus. Different medical parts exhibit distinct modern pharmacolog
Externí odkaz:
https://doaj.org/article/f2a154b3b34f493eb4a81339ee858bc8
Autor:
Hongli Li, Yejun Tan, Xin Cheng, Zheyu Zhang, Jianhua Huang, Shan Hui, Lemei Zhu, Yuqing Liu, Di Zhao, Zhao Liu, Weijun Peng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: Bushen Tiansui Formula (BSTSF) is a traditional formulation of Chinese medicine that has been used to treat Alzheimer’s disease (AD) for decades; however, the underlying mechanisms by which this formula achieves such therapeutic effects
Externí odkaz:
https://doaj.org/article/300352a7eb854f06962cdd320c0f1a42
Autor:
Heng Cai, Lin-Yan Huang, Rui Hong, Jin-Xiu Song, Xin-Jian Guo, Wei Zhou, Zhao-Li Hu, Wan Wang, Yan-Ling Wang, Jian-Gang Shen, Su-Hua Qi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Plant exosome-like nanoparticles (ELNs) have shown great potential in treating tumor and inflammatory diseases, but the neuroprotective effect of plant ELNs remains unknown. In the present study, we isolated and characterized novel ELNs from Momordic
Externí odkaz:
https://doaj.org/article/43ba6dc420ac4b5d982e974d610cbb93