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Autor:
Xing-Min Zhang, Yue-Chang Huang, Bai-Zhong Chen, Qian Li, Pan-Pan Wu, Wen-Hua Chen, Ri-Hui Wu, Chen Li
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionAlcohol consumption alters the diversity and metabolic activities of gut microbiota, leading to intestinal barrier dysfunction and contributing to the development of alcoholic liver disease (ALD), which is the most prevalent cause of adva
Externí odkaz:
https://doaj.org/article/a3855b96136c4dac9f5b7ed0cf7094bf
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionDiabetic nephropathy (DN) is the leading cause of end-stage renal disease. Due to its complex pathogenesis, new therapeutic agents are urgently needed. Orthosiphon aristatus (Blume) Miq., commonly known as kidney tea, is widely used in DN
Externí odkaz:
https://doaj.org/article/b3aed8f474424eadba05aee807db266c
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Heart failure (HF) is a chronic condition that progressively worsens and continues to be a major financial burden and public health concern. The “gut-heart” axis provides an innovative perspective and therapeutic strategy for preventing and treat
Externí odkaz:
https://doaj.org/article/ecdc29d684ca46449f9202ab2d7f1e2c
Autor:
Chaoyou Lin, Dawei Song, Shangwen Wang, Yunfei Chu, Changxing Chi, Sining Jia, Mengyi Lin, Chenbei He, Chengxi Jiang, Fanghua Gong, Qiongzhen Chen
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Ulcerative colitis (UC) is a chronic inflammatory bowel disease characterized inflammatory imbalance, intestinal epithelial mucosal damage, and dysbiosis of the gut microbiota. Polygonatum cyrtonema polysaccharides (PCPs) can regulate gut microbiota
Externí odkaz:
https://doaj.org/article/231f0ce5ab57447ca851dc854b34fa77
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Background: Diabetic nephropathy (DN) is known as the most common complication of diabetes, resulting from a complex inheritance-environment interaction without effective clinical treatments. Herein, we revealed the protective effects and mechanisms
Externí odkaz:
https://doaj.org/article/9956d7b326db4281801aab23bab19aba
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionUlcerative colitis (UC) is marked by recurring inflammation. Existing treatments are ineffective and may have toxic side effects. Thus, new therapeutic agents are urgently needed. We studied the botanical formula “Li-Hong Tang (LHT)", w
Externí odkaz:
https://doaj.org/article/33dafb0b2c864441b07e6e36248110d0
Autor:
Yanmiao Ma, Xiuhong Wei, Jiehao Peng, Fuxia Wei, Ya Wen, Mingran Liu, Bo Song, Yonghui Wang, Yumin Zhang, Tao Peng
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionEphedra sinica polysaccharide (ESP) exerts substantial therapeutic effects on rheumatoid arthritis (RA). However, the mechanism through which ESP intervenes in RA remains unclear. A close correlation has been observed between enzymes and
Externí odkaz:
https://doaj.org/article/2846474ec40a45b48efaf327bc5ecd7d
Autor:
Jingyi Xu, Lei Zhou, Zhaowei Chen, Yuezhu Wang, Fang Xu, Qun Kuang, Yixuan Zhang, Huajun Zheng
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: The prevalence of major depressive disorder (MDD) has gradually increased and has attracted widespread attention. The aim of this study was to investigate the effect of a probiotic compound consisting of Bacillus coagulans and Clostridi
Externí odkaz:
https://doaj.org/article/f488c10d0b7a410abb383e188b07c44a
Autor:
Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
During the past half-century, although numerous interventions for obesity have arisen, the condition’s prevalence has relentlessly escalated annually. Obesity represents a substantial public health challenge, especially due to its robust correlatio
Externí odkaz:
https://doaj.org/article/1a0ef4cffe9b4113afa5f2271f4e4f0d
Autor:
Dongliang Chen, Yuanfei Wang, Jianmei Yang, Wanyi Ou, Guiru Lin, Ze Zeng, Xiaomin Lu, Zumin Chen, Lili Zou, Yaling Tian, Aiping Wu, Shelley E. Keating, Qinhe Yang, Chenli Lin, Yinji Liang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Purpose: The prevalence of non-alcoholic fatty liver disease (NAFLD) and its related mortality is increasing at an unprecedented rate. Traditional Chinese medicine (TCM) has been shown to offer potential for early prevention and treatment of NAFLD. T
Externí odkaz:
https://doaj.org/article/cf35e8d0b21b4e52a8871ef3a3d636ba