Zobrazeno 71 - 80
of 261
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Gut microbiota mediated hypoglycemic effect of Astragalus membranaceus polysaccharides in db/db mice
Autor:
Qianbo Song, Sau Wan Cheng, Dan Li, Huiyuan Cheng, Yuen Sze Lai, Quanbin Han, Hoi Yan Wu, Pang Chui Shaw, Zhong Zuo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Gut microbiota has been reported to be closely associated with Type-II diabetes. Restoration of disordered gut microbiota ecosystem has been developed into a therapeutic strategy and gradually applied on Type-II diabetes treatment with both western d
Externí odkaz:
https://doaj.org/article/e3b1f460046d4951b8218768a9cdf701
Autor:
Jing-Jing Xu, Feng Xu, Wei Wang, Peng-Pu Wang, Jing Xian, Xing Han, Ming-Ying Shang, Guang-Xue Liu, Xuan Wang, Shao-Qing Cai
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cholestasis is the most destructive pathological manifestation of liver disease and available treatments are very limited. Paeoniae Radix Rubra (PRR) is an important traditional Chinese drug used to treat cholestasis. This study combined targeted met
Externí odkaz:
https://doaj.org/article/cc18bf7b980e4062a3834dfbb0fdc651
Autor:
Yueqiu Liu, Xinyi Hu, Wen Zheng, Lu Zhang, Luolan Gui, Ge Liang, Yong Zhang, Liqiang Hu, Xin Li, Yi Zhong, Tao Su, Xin Liu, Jingqiu Cheng, Meng Gong
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The 9-(R)-HODE is an active compound isolated from cortex lycii that showed significant hypoglycemic effects in our previous in vitro study. In this study, 9-(R)-HODE’s in vivo hypoglycemic activity and effect on alleviating diabetic complications,
Externí odkaz:
https://doaj.org/article/ba6f5ddde2ad489e91c1a896e9cbb886
Autor:
Ruolin Gao, Xiangjing Meng, Yili Xue, Min Mao, Yaru Liu, Xuewen Tian, Bo Sui, Xun Li, Pengyi Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Type 2 diabetes mellitus (T2DM) occurs that cannot effectively use the insulin. Insulin Resistance (IR) is a significant characteristic of T2DM which is also an essential treatment target in blood glucose regulation to prevent T2DM and its complicati
Externí odkaz:
https://doaj.org/article/80f16fbbcfac46f89d25c0ef5019df28
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Metformin and pioglitazone monotherapy have been proven to alter gut microbiota in diabetes and obesity. The present study aimed to investigated whether the combined administration of pioglitazone and metformin achieved superior protective effects on
Externí odkaz:
https://doaj.org/article/7663efe243314660b8bcb5bc28495b75
Autor:
Ke Sui, Kevin M. Tveter, Fiona G. Bawagan, Patricia Buckendahl, Savannah A. Martinez, Zehra H. Jaffri, Avery T. MacDonell, Yue Wu, Rocio M. Duran, Sue A. Shapses, Diana E. Roopchand
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Externí odkaz:
https://doaj.org/article/a27e862de22f4ad6a77625c7413a5e9d
Autor:
Shiyue Luo, Lixiao Zhou, Xuejun Jiang, Yinyin Xia, Lishuang Huang, Run Ling, Shixin Tang, Zhen Zou, Chengzhi Chen, Jingfu Qiu
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Asparagus cochinchinensis is a valuable traditional Chinese medicine that has anti-inflammatory ability and effectively regulates the dysbiosis within the body. Obesity is usually characterized by chronic low-grade inflammation with aberrant gut micr
Externí odkaz:
https://doaj.org/article/6aebf8dec1a14a26b8e93ee70fb3e83e
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Ginsenoside Rb1, a main component of ginseng, is often transformed into ginsenoside CK by intestinal flora to exert various pharmacological activity. However, it remains unclear whether ginsenoside CK is responsible for the anti-gastric cancer effect
Externí odkaz:
https://doaj.org/article/b10c2b320c3b4099ba6944cc0cf22c56
Autor:
Hui Xu, Li-Bin Pan, Hang Yu, Pei Han, Jie Fu, Zheng-Wei Zhang, Jia-Chun Hu, Xin-Yu Yang, Adili Keranmu, Hao-Jian Zhang, Meng-Meng Bu, Jian-Dong Jiang, Yan Wang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The gut microbiota plays an important role in inflammatory diseases. Metabolites in the three metabolic pathways of tryptophan (Trp), histidine (His), and phenylalanine (Phe) can affect various inflammatory conditions, such as obesity, diabetes, arth
Externí odkaz:
https://doaj.org/article/7898b012f74941248f153964d27ed717
Autor:
Zili Lei, Lei Chen, Qing Hu, Yanhong Yang, Fengxue Tong, Keying Li, Ting Lin, Ya Nie, Hedong Rong, Siping Yu, Qi Song, Jiao Guo
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Intestinal aging seriously affects the absorption of nutrients of the aged people. Ginsenoside Rb1 (GRb1) which has multiple functions on treating gastrointestinal disorders is one of the important ingredients from Ginseng, the famous herb in traditi
Externí odkaz:
https://doaj.org/article/34ae75fb8d954c26a6ca81cff64dbba9