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Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Accumulating evidence suggests that dysregulation of the intestinal flora potentially contributes to the occurrence and development of nonalcoholic fatty liver disease (NAFLD). Phyllanthus emblica (PE), an edible and medicinal natural resource, exert
Externí odkaz:
https://doaj.org/article/04ad5ccf499b4731989a87b54fb10298
Autor:
Hu Li, Nan-Nan Liu, Jian-Rui Li, Biao Dong, Mei-Xi Wang, Jia-Li Tan, Xue-Kai Wang, Jing Jiang, Lei Lei, Hong-Ying Li, Han Sun, Jian-Dong Jiang, Zong-Gen Peng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Nonalcoholic fatty liver disease (NAFLD), ranging from simple steatosis to nonalcoholic steatohepatitis (NASH), is a liver disease worldwide without approved therapeutic drugs. Anti-inflammatory and hepatoprotective drug bicyclol and multi-pharmacolo
Externí odkaz:
https://doaj.org/article/e6cbf5bb267341f4972f2dfeb692ca96
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Bile acid (BA) metabolism is an attractive therapeutic target in nonalcoholic fatty liver disease (NAFLD). We aimed to investigate the effect of ilexsaponin A1 (IsA), a major bioactive ingredient of Ilex, on high-fat diet (HFD)-induced NAFLD in mice
Externí odkaz:
https://doaj.org/article/33413a820b5b4a048f05c3b814c2e3ec
Autor:
Wenyi Liang, Kun Zhou, Ping Jian, Zihao Chang, Qiunan Zhang, Yuqi Liu, Shuiming Xiao, Lanzhen Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Ginseng, the root and rhizome of Panax ginseng C. A. Mey., is a famous herbal medicine, and its major ginsenosides exert beneficial effects on nonalcoholic fatty liver disease (NAFLD). Due to the multicomponent and multitarget features of ginsenoside
Externí odkaz:
https://doaj.org/article/aca1a8da5df747cb8442ab3ac582dcbe
Autor:
Huantian Cui, Yuting Li, Yuming Wang, Lulu Jin, Lu Yang, Li Wang, Jiabao Liao, Haoshuo Wang, Yanfei Peng, Zhaiyi Zhang, Hongwu Wang, Xiangguo Liu
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
The dysbiosis in gut microbiota could affect host metabolism and contribute to the development of nonalcoholic fatty liver disease (NAFLD). Da-Chai-Hu decoction (DCH) has demonstrated protective effects on NAFLD, however, the exact mechanisms remain
Externí odkaz:
https://doaj.org/article/a7ce89980a5a4fb8aa8c0fb61336b0fe