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Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Breast cancer has recently been known as the first lethal malignancy in women worldwide. Despite the existing treatments that have improved the patients’ prognosis, some types of breast cancer are serious challenges to treat. Therefore, efforts are
Externí odkaz:
https://doaj.org/article/4942ca62a29f4425a98b552441974bca
Autor:
Yihang Qi, Wenxiang Zhang, Ray Jiang, Olivia Xu, Xiangyi Kong, Lin Zhang, Yi Fang, Jingping Wang, Jing Wang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Background: The combination of immune checkpoint inhibitors (ICIs) and chemotherapy (CT) is a new strategy to explore cancer treatment in recent years, and it is also practiced in triple-negative breast cancer (TNBC). However, several published rando
Externí odkaz:
https://doaj.org/article/e03066709672448dae46c21756b089d2
Autor:
Panayiota Christodoulou, Panagiotis Boutsikos, Christiana M. Neophytou, Theodora-Christina Kyriakou, Maria-Ioanna Christodoulou, Panagiotis Papageorgis, Anastasis Stephanou, Ioannis Patrikios
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Amygdalin is a naturally occurring glycoside used in traditional Chinese medicine and is known to have anti-cancer properties. Even though the anti-cancer properties of amygdalin are well known, its effect on normal cells has not been thoroughly inve
Externí odkaz:
https://doaj.org/article/6c6697748d8b44b5a3f06f4b2acaa6ab
Autor:
Md Shahin Alam, Adiba Sultana, Hongyang Sun, Jin Wu, Fanfan Guo, Qing Li, Haigang Ren, Zongbing Hao, Yi Zhang, Guanghui Wang
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Accurate identification of molecular targets of disease plays an important role in diagnosis, prognosis, and therapies. Breast cancer (BC) is one of the most common malignant cancers in women worldwide. Thus, the objective of this study was to accura
Externí odkaz:
https://doaj.org/article/9b9dfba8d4a44b6a999a9fe68b03f8f6
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Breast cancer is one of the most common malignancies and the leading cause of cancer-related death in women. HER2 overexpression is a factor for poor prognosis in breast cancer, and anti-HER2 therapy improves survival in these patients. A dual-target
Externí odkaz:
https://doaj.org/article/9e5913302a3c4cfd8d82770d1dd162c3
Autor:
Catherine Goetzinger, Caroline Alleaume, Anna Schritz, Bernard Vrijens, Marie Préau, Guy Fagherazzi, Laetitia Huiart
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Introduction: Up to 50% of breast cancer (BC) survivors discontinue their adjuvant endocrine therapy (AET) before the recommended 5 years, raising the issue of medication non-adherence. eHealth technologies have the potential to support patients to e
Externí odkaz:
https://doaj.org/article/6c3495448e6c4b9fa73f5152c2ba3535
Autor:
Jianwei Feng, Xinyue Meng
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Dysregulated epigenetic enzymes and resultant abnormal epigenetic modifications (EMs) have been suggested to be closely related to tumor occurrence and progression. Histone modifications (HMs) can assist in maintaining genome stability, DNA repair, t
Externí odkaz:
https://doaj.org/article/d0f404cb572b48aa9e1058b941a4dc84
Autor:
Fahimeh Salehi, Hossein Behboudi, Elaheh Salehi, Sussan K. Ardestani, Firoozeh Piroozmand, Gholamreza Kavoosi
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Zataria multiflora essential oil (ZEO) is a natural complex of compounds with a high apoptotic potential against breast cancer cells and minor toxicity toward normal cells; however, similar to many essential oils, ZEO utilization in pharmaceutical in
Externí odkaz:
https://doaj.org/article/d8d41b014f3442b3a6f5e8074f3e6863
Autor:
Rita De Sanctis, Flavia Jacobs, Chiara Benvenuti, Mariangela Gaudio, Raul Franceschini, Richard Tancredi, Paolo Pedrazzoli, Armando Santoro, Alberto Zambelli
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
To date, only few marine natural compounds have been proved to be active in breast cancer (BC). The main marine-derived drugs that have been studied for the treatment of BC are tubulin-binding agents (eribulin and plocabulin), DNA-targeting agents (c
Externí odkaz:
https://doaj.org/article/a52aa929a4fd4377b96d47780f1ba585
Autor:
Umar Mehraj, Nissar Ahmad Wani, Abid Hamid, Mustfa Alkhanani, Abdullah Almilaibary, Manzoor Ahmad Mir
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Although advances in diagnostics and therapeutics have prolonged the survival of triple-negative breast cancer (TNBC) patients, metastasis, therapeutic resistance, and lack of targeted therapies remain the foremost hurdle in the effective management
Externí odkaz:
https://doaj.org/article/e25dcab2afa949f89ef3b4c3de36057d