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Autor:
Pankaj Kumar, Bharti Mangla, Shamama Javed, Waquar Ahsan, Pankaj Musyuni, Durgaramani Sivadasan, Saad S. Alqahtani, Geeta Aggarwal
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Breast cancer being one of the most frequent cancers in women accounts for almost a quarter of all cancer cases. Early and late-stage breast cancer outcomes have improved dramatically, with considerable gains in overall survival rate and disease-free
Externí odkaz:
https://doaj.org/article/34b3c305b38543a59f4c0f3036cd5651
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Breast cancer (BC) is the most frequently diagnosed malignant tumor among women in the world. BC is the heterogeneous tumor with different subtypes including luminal A-like, luminal B-like (HER2-/HER2+), HER2 enriched, and triple-negative BC. The the
Externí odkaz:
https://doaj.org/article/1966b3df8acb406bae14dbc4a5e70587
Autor:
Hairong Zeng, Chao Xia, Bei Zhao, Mengmeng Zhu, HaoYue Zhang, Die Zhang, Xin Rui, Huili Li, Yi Yuan
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2022)
Bufalin (Buf), an active ingredient of the traditional Chinese medicine Chansu, is known to have anticancer effects for breast cancer. However, its poor solubility, high toxicity, and extensive side effects limit its use. Metal-organic frameworks (MO
Externí odkaz:
https://doaj.org/article/19d8716aad9c4b4cbed3bda0b45aadd4
Autor:
Huan Zhang, Jinshun Xu, Binyang Gao, Hong Wang, Jianbo Huang, Jie Zhou, Rui Yang, Feng Yan, Yulan Peng
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
Background: Triple-negative breast cancer (TNBC) is the most aggressive subtype of breast cancer with very few treatment options. Although tumor-targeted nanomedicines hold great promise for the treatment of TNBC, the tumor microenvironment (TME) con
Externí odkaz:
https://doaj.org/article/c0819588dc934348a66a97d8fb9a43ce
Autor:
Nigel Bush, Andrew Healey, Anant Shah, Gary Box, Vladimir Kirkin, Sue Eccles, Per Christian Sontum, Spiros Kotopoulis, Svein Kvåle, Annemieke van Wamel, Catharina de Lange Davies, Jeffrey Bamber
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
IntroductionAcoustic cluster therapy (ACT) comprises co-administration of a formulation containing microbubble/microdroplet clusters (PS101), together with a regular medicinal drug (e.g., a chemotherapeutic) and local ultrasound (US) insonation of th
Externí odkaz:
https://doaj.org/article/f2bf4ce5386d49caa1e0235ee5b4f708
Publikováno v:
Frontiers in Pharmacology, Vol 7 (2016)
Accumulating evidences have suggested the existence of breast cancer stem cells (BCSCs), which possess the potential of both self-renewal and differentiation. The origin of BCSCs might have relationship to the development of normal mammary stem cells
Externí odkaz:
https://doaj.org/article/f49d3d3a5f0a41dd9e9e3168e44399d1