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Autor:
Şeyma Ulusoy, Ebrar İnal, Esra Küpeli Akkol, Mahmut Çiçek, Murat Kartal, Eduardo Sobarzo-Sánchez
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
The aim of this study was to investigate the effects of S. nigra L. and V. agnus-castus L. plants on obesity in vivo. Extracts were prepared from S. nigra leaves, flowers, fruits and from V. agnus-castus leaves, flowers, and fruits using 100% water a
Externí odkaz:
https://doaj.org/article/f75f47b21928424f99d379ebc3cdbc73
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/e9048bdb02bf4bcb9452343253d5f90e
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Metabolic syndrome (MetS) represents a constellation of metabolic abnormalities, typified by obesity, hypertension, hyperglycemia, and hyperlipidemia. It stems from intricate dysregulations in metabolic pathways governing energy and substrate metabol
Externí odkaz:
https://doaj.org/article/174fe159ae104101bb1879b600fae8ba
A real-world data analysis of tirzepatide in the FDA adverse event reporting system (FAERS) database
Autor:
Liyuan Liu
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundTirzepatide, a glucose-dependent insulinotropic polypeptide (GIP) receptor and glucagon-like peptide-1 (GLP-1) receptor agonist, is indicated for chronic weight management in adults with obesity or overweight as an adjunct to a reduced-calo
Externí odkaz:
https://doaj.org/article/5a139945b8834632a898eadf96d1fea9
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objective: Browning of white adipocytes is considered an efficient approach to combat obesity. Rosiglitazone induces the thermogenetic program of white adipocytes, but the underlying mechanisms remain elusive.Methods: Expression levels of browning an
Externí odkaz:
https://doaj.org/article/10465de402234b04b96ed3c630db3048
Autor:
Marzia Friuli, Christian Sepe, Elisabetta Panza, Cristina Travelli, Irene Paterniti, Adele Romano
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Unhealthy lifestyle habits including a sedentary life, the lack of physical activity, and wrong dietary habits are the major ones responsible for the constant increase of obesity and metabolic disorders prevalence worldwide; therefore, the scientific
Externí odkaz:
https://doaj.org/article/85ec3a17776647cfa959ddc8c6a6a4d6
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
AimThe aim of this study was to develop a vancomycin population pharmacokinetic model in adult obese patients and propose covariate-based dosing individualization in order to maximize the achievement of the newly recommended PK/PD target, according t
Externí odkaz:
https://doaj.org/article/5b2cc96764f2490cae05e069b724d2cb
Autor:
Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
During the past half-century, although numerous interventions for obesity have arisen, the condition’s prevalence has relentlessly escalated annually. Obesity represents a substantial public health challenge, especially due to its robust correlatio
Externí odkaz:
https://doaj.org/article/1a0ef4cffe9b4113afa5f2271f4e4f0d
Autor:
Andrés David Turizo-Smith, Samantha Córdoba-Hernandez, Lidy Vannessa Mejía-Guarnizo, Paula Stefany Monroy-Camacho, Josefa Antonia Rodríguez-García
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Chronic inflammation plays a crucial role in the onset and progression of pathologies like neurodegenerative and cardiovascular diseases, diabetes, and cancer, since tumor development and chronic inflammation are linked, sharing common signaling path
Externí odkaz:
https://doaj.org/article/3dbf845b378042f79accea200f768ef2
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
BackgroundFor cesarean delivery (CD), the 90% effective dosage (ED90) of oxytocin for a first bolus has been established. It is not yet known how much oxytocin to inject into obese women undergoing elective discectomy to keep their uterine tone (UT)
Externí odkaz:
https://doaj.org/article/2d4047482ed14d71bfe1da751023b3e8