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Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Effect of peripheral cannabinoid receptor 1 (CB1R) blockade by AM6545 in the monosodium glutamate (MSG)-induced hypometabolic and hypothalamic obesity was observed, and the impact on intraperitoneal adipose tissue and adipokines was investigated. The
Externí odkaz:
https://doaj.org/article/4ebf5e51389a4cd7b69e655d2a3db190
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The clinical development of the first generation of globally active cannabinoid 1 receptor (CB1R) antagonists was suspended because of their adverse neuropsychiatric effects. Selective blockade of peripheral CB1Rs has the potential to provide a viabl
Externí odkaz:
https://doaj.org/article/2dbc468e093441e0a496357f10b1fe43