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Autor:
Yanting Lin, Rui Gao, Dongquan Jing, Yiming Liu, Huijuan Da, Lutz Birnbaumer, Yong Yang, Xinghua Gao, Zhenhua Gao, Qiuhua Cao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
During the past half-century, although numerous interventions for obesity have arisen, the condition’s prevalence has relentlessly escalated annually. Obesity represents a substantial public health challenge, especially due to its robust correlatio
Externí odkaz:
https://doaj.org/article/1a0ef4cffe9b4113afa5f2271f4e4f0d
Autor:
Wanqing Li, Hongxiang Zeng, Min Xu, Chenglong Huang, Linfen Tao, Jun Li, Ting Zhang, Hong Chen, Jing Xia, Chunli Li, Xi Li
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
The chronic low-grade inflammation of adipose tissues, primarily mediated by adipose tissue macrophages (ATMs), is the key pathogenic link between obesity and metabolic disorders. Oleanolic acid (OA) is a natural triterpenoid possessing anti-diabetic
Externí odkaz:
https://doaj.org/article/47a5da3dfcd64a5faeb24afe17ac13f7
Autor:
Jiali Yang, Yunhui Ran, Yonghui Yang, Shuyi Song, Yahong Wu, Yuanming Qi, Yanfeng Gao, Guodong Li
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2021)
In obesity, macrophages and other immune cells accumulate in organs affected by insulin, leading to chronic inflammation and insulin resistance. 4-Hydroxyisoleucine (4-HIL) is a non-protein amino acid found in fenugreek seeds. 4-HIL enhances insulin
Externí odkaz:
https://doaj.org/article/a24eab1688984476ae0d8423b7f98dd9