Zobrazeno 1 - 10
of 22 549
pro vyhledávání: ''
Autor:
Panpan Ye, Jinyi Shi, Zixuan Guo, Xinmei Yang, Qian Li, Keguang Chen, Furong Zhao, Haiyan Zhou, Yehui Zhang, John van den Anker, Linlin Song, Wei Zhao
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
ObjectivePiperacillin/tazobactam (PIP/TAZ) is used for the treatment of lower respiratory tract bacterial infections in children. This study was performed to evaluate if the current dosing regimen results in therapeutic drug concentrations.Patients a
Externí odkaz:
https://doaj.org/article/0a772b0cd0dc46e390310dcbcc92573e
Autor:
Maxime Pluquet, Marie Metzger, Christian Jacquelinet, Christian Combe, Denis Fouque, Maurice Laville, Luc Frimat, Ziad A. Massy, Sophie Liabeuf, Solène M. Laville
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Adjusting drug dose levels based on equations that standardize the estimated glomerular filtration rate (eGFR) to a body surface area (BSA) of 1.73 m2 can pose challenges, especially for patients with extremely high or low body mass ind
Externí odkaz:
https://doaj.org/article/77673210426f4a55aed8fdda6559eb00
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Wolfberry, esteemed as a traditional Chinese medicinal material and functional food, is replete with nutrients and boasts a diverse array of health benefits, including hypoglycemic, antitumor, antioxidant, anti-inflammatory, and immune-enhancing prop
Externí odkaz:
https://doaj.org/article/0c0b8582b9f747b8962c05e3839a84d5
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Introduction: Following the introduction of incretin-based drugs to the market, instances of acute pancreatitis have been reported, leading the FDA to mandate a warning label. Incretin-based therapy has been linked to a rare yet significant adverse e
Externí odkaz:
https://doaj.org/article/d82946e4340246c4adb8003cd2f5bd22
Autor:
Shuyi Wu, Haiping Wang, Chunbao Li, Jingjing Tao, Xiaoli Zhu, Hengfen Dai, Hongfan Duan, Tian Hu, Miao Li, Fenfen Qu, Yun Wei, Chunhua Wang, Jinhua Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionStudies on the use of direct oral anticoagulants (DOACs) for preventing venous thromboembolism (VTE) in hospitalized cancer patients are lacking. Therefore, we conducted a multicenter retrospective cohort study to evaluate the efficacy an
Externí odkaz:
https://doaj.org/article/0e22e153c2a546e0afdb71a3f633f4e1
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Objective: To conduct a meta-analysis of the effectiveness and safety of ginkgo biloba extract combined with donepezil hydrochloride vs. donepezil for the treatment of vascular dementia (VaD).Methods: Four English databases (PubMed, EMBASE, Web of Sc
Externí odkaz:
https://doaj.org/article/f314652ebd5b426cb4684bfc1a548cda
Autor:
Chen-Fei Fu, Jian-Long Li, Jia-Wei Chen, Hao Liang, Wen-Rui Zhao, Shi-Yu He, Xiao-Wei Ma, Xiao-Fan Yang, He-Lin Wang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Sepsis is a complex syndrome characterized by multi-organ dysfunction, due to the presence of harmful microorganisms in blood which could cause mortality. Complications associated with sepsis involve multiple organ dysfunction. The pathogenesis of se
Externí odkaz:
https://doaj.org/article/7a9fd25d366c4148b15419cb662d356b
Autor:
Manuel E. Machado-Duque, Lina Camacho-Arteaga, Mónica Sabaté, Xavier Vidal-Guitart, Jorge E. Machado-Alba
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
IntroductionIn-hospital falls are multicausal in older hospitalized patients. Drugs with anticholinergic load and psychotropic effects can increase the risk of falling.ObjectiveThis study aimed to determine the associations between fall risk-increasi
Externí odkaz:
https://doaj.org/article/b5e8850003234538ac7222ae3eab29f1
Autor:
Wencan Li, Xiang Liu, Zheng Liu, Qichang Xing, Renzhu Liu, Qinxuan Wu, Yixiang Hu, Jiani Zhang
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Diabetic cardiomyopathy (DCM) is a myocardial-specific microvascular disease caused by diabetes that affects the structure and function of the heart and is considered to be the leading cause of morbidity and death in patients with diabetes. Currently
Externí odkaz:
https://doaj.org/article/40135471f35b47ba986673c058bed8f7
Autor:
Vivien R. Sutton, Sally V. Watt, Hedieh Akhlaghi, David C. Cipolla, Kuan-Ju Chen, Daniel LaSala, Patrick P. McDonald, Paul A. Beavis, Isabelle Munoz, Adrian W. Hodel, Tahereh Noori, Ilia Voskoboinik, Joseph A. Trapani
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Recently developed small-molecule inhibitors of the lysosomal protease dipeptidyl peptidase 1 (DPP1), also known as cathepsin C (CatC), can suppress suppurative inflammation in vivo by blocking the processing of zymogenic (pro-) forms of neutrophil s
Externí odkaz:
https://doaj.org/article/637ceae3f9ef4a27add5a0ac7f8e1bc1