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Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Lung adenocarcinoma (LUAD) is the major subtype of lung cancer and has a poor prognosis. Disulfidptosis is a novel regulated cell death form characterized by aberrant disulfide stress and actin network collapse. This study aimed to identi
Externí odkaz:
https://doaj.org/article/af66d084d2e04bb4a2134b551a197926
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: As a new drug delivery and embolization system, drug-eluted bronchial artery chemoembolization (DEB-BACE) can not only embolize the tumor blood supply artery but also load chemotherapy drugs and slowly release them into the local environm
Externí odkaz:
https://doaj.org/article/7fdfc961c8db46429cf9aebbb8de493d
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: T cell exhaustion (TEX) heterogeneity leads to unfavorable immunotherapeutic responses in patients with cancer. Classification of TEX molecular phenotypes is pivotal to overcoming TEX and improving immunotherapies in the clinical setting.
Externí odkaz:
https://doaj.org/article/6110cf3e2749415d8d0b6e81f100d9ec
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Background: Although the role of tumor microenvironment in lung adenocarcinoma (LUAD) has been explored in a number of studies, the value of TME-related signatures in immunotherapy has not been comprehensively characterized.Materials and Methods: Con
Externí odkaz:
https://doaj.org/article/fc3c0e224cad4e1fb6f87bc566aabdf1
Identification of cuproptosis-related subtypes in lung adenocarcinoma and its potential significance
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
Cuproptosis is a novel and unique cell death mode that has attracted significant interest in recent years. Little is currently known about whether cuproptosis-related genes (CRGs) are associated with the pathophysiology and survival of patients with
Externí odkaz:
https://doaj.org/article/9dbfa131fafc4d48a35bed51ca244370