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Autor:
Lu Zhan, Fangting Su, Qiang Li, Yueqiang Wen, Feng Wei, Zhelin He, Xiaoyan Chen, Xiang Yin, Jian Wang, Yilin Cai, Yuxia Gong, Yu Chen, Xiao Ma, Jinhao Zeng
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
Colorectal cancer (CRC) is the third most common malignant tumor in the world, and it is prone to recurrence and metastasis during treatment. Aerobic glycolysis is one of the main characteristics of tumor cell metabolism in CRC. Tumor cells rely on g
Externí odkaz:
https://doaj.org/article/8f5a7bf7079e45faa29c4c576b92d7f4
Autor:
Chao Yang, An-Jie Xia, Cheng-Hao Du, Ming-Xing Hu, You-Ling Gong, Rong Tian, Xin Jiang, Yong-Mei Xie
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
7-Ethyl-10-hydroxycamptothecin (SN38), a highly potent metabolite of irinotecan, has an anticancer efficacy 100–1000 folds more than irinotecan in vitro. However, the clinical application of SN38 has been limited due to the very narrow therapeutic
Externí odkaz:
https://doaj.org/article/e29381d4fc0a44f2bb2a31f7f93c545e
Publikováno v:
Frontiers in Pharmacology, Vol 8 (2017)
The study under investigation focuses on in vitro antiproliferative efficacy of the flavonoid morin and the mechanisms by which it inhibits the growth of colon cancer using SW480 colon cancer cells with emphasis on Warburg effect. It was found that t
Externí odkaz:
https://doaj.org/article/0604c5a84ee54cf782202ce4e74f795d