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Autor:
Mohammad Malekan, Nicholas Denko, Lorenzo Mortara, Appu Rathinavelu, Mohammad Mahdi Parvizi, Umamaheswari Natarajan
Publikováno v:
Frontiers in Pharmacology, Vol 15 (2024)
Externí odkaz:
https://doaj.org/article/4b677702cef2470ea608de9013bbf3d1
Publikováno v:
Frontiers in Pharmacology, Vol 14 (2023)
The widespread clinical use of statins has contributed to significant reductions of cardiovascular morbidity and mortality. Increasing preclinical and epidemiological evidences have revealed that dyslipidemia is an important risk factor for carcinoge
Externí odkaz:
https://doaj.org/article/60957519de0a4305962396a32ac5b70e
Publikováno v:
Frontiers in Pharmacology, Vol 13 (2022)
The synthetic hexapeptide WKYMVm, screened from a synthetic peptide library, has been identified as an agonist of FPRs with the strongest activating effect on FPR2. WKYMVm plays an anti-inflammatory role in most inflammatory diseases by increasing th
Externí odkaz:
https://doaj.org/article/bda65a692c784af7b7cac4d1b744a327
Publikováno v:
Frontiers in Pharmacology, Vol 12 (2021)
microRNAs (miRs) are short, non-coding RNAs that regulate gene expression by mRNA degradation or translational repression. Accumulated studies have demonstrated that miRs participate in various biological processes including cell differentiation, pro
Externí odkaz:
https://doaj.org/article/be3ca5e75b3f4c5da9fcd9ed7569a3c9
Publikováno v:
Frontiers in Pharmacology, Vol 11 (2020)
Aim: Angiogenesis plays an important role in the initiation, development, and metastasis of malignant tumors. Antiangiogenic drugs combined with immune therapy are considered to have a synergistic effect on anti-tumor strategy. Weichang’an formula
Externí odkaz:
https://doaj.org/article/a37b0d1156ab4ae2b782c03370f84d2a
Publikováno v:
Frontiers in Pharmacology, Vol 10 (2019)
Hypoxia-inducible factor-1 (HIF-1)–induced angiogenesis has been involved in numerous pathological conditions, and it may be harmful or beneficial depending on the types of diseases. Exploration on angiogenesis has sparked hopes in providing novel
Externí odkaz:
https://doaj.org/article/ba65e62fc9d54e759ee0a645308d1308
Autor:
Aeyung Kim, Jin Yeul Ma
Publikováno v:
Frontiers in Pharmacology, Vol 9 (2018)
Several components isolated from Glycyrrhizae radix rhizome (GR), including glycyrrhizin, liquiritin, and liquiritigenin, have been shown to induce cancer cell death and inhibit cancer metastasis. Isoliquiritin apioside (ISLA), a component isolated f
Externí odkaz:
https://doaj.org/article/84d3c80e9893410bbf696cdc40885b2c
Publikováno v:
Frontiers in Pharmacology, Vol 6 (2015)
Thrombospondin-1 (TSP-1) is a large matricellular glycoprotein known to be overexpressed within tumor stroma in several cancer types. While mainly considered as an endogenous angiogenesis inhibitor, TSP-1 exhibits multifaceted functionalities in a tu
Externí odkaz:
https://doaj.org/article/e165adc1a72d497798a1695c5c501254