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Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1112 (2024)
OBJECTIVES:. To review recruitment and retention strategies of randomized family-centered interventional studies in adult ICUs. DATA SOURCES:. The MEDLINE, Embase, PsycINFO, CINAHL, and the Cochrane Library database from inception to February 2023. S
Externí odkaz:
https://doaj.org/article/2060d47dfb4e4ba6867ad03bed1821ba
Autor:
Matthew R. Woodward, DO, Chris L. Wells, PhD, Shannon Arnold, BA, Farra Dorman, PT, Zaka Ahmed, MBBS, Nicholas A. Morris, MD, Prajwal Ciryam, MD, PhD, Jamie E. Podell, MD, Wan-Tsu W. Chang, MD, W. Denney Zimmerman, DO, Melissa Motta, MD, Bilal Butt, MD, Melissa B. Pergakis, MD, Mohamed Labib, MD, Ting I. Wang, MA, Brian L. Edlow, MD, Neeraj Badjatia, MD, Robynne Braun, MD, PhD, Gunjan Y. Parikh, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1101 (2024)
OBJECTIVES:. Accurate classification of disorders of consciousness (DoC) is key in developing rehabilitation plans after brain injury. The Coma Recovery Scale—Revised (CRS-R) is a sensitive measure of consciousness validated in the rehabilitation p
Externí odkaz:
https://doaj.org/article/7c5c673a96624eaf8f9851329fd30bd1
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1113 (2024)
CONTEXT:. Amid the COVID-19 pandemic, this study delves into ventilator shortages, exploring simple split ventilation (SSV), simple differential ventilation (SDV), and differential multiventilation (DMV). The knowledge gap centers on understanding th
Externí odkaz:
https://doaj.org/article/123ec3b1c4544b168e02511cfd8912e6
Autor:
Abigail M. Samuelsen, BS, E. Scott Halstead, MD, PhD, Erik B. Lehman, MS, Daniel J. McKeone, MD, Anthony S. Bonavia, MD
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1106 (2024)
OBJECTIVES:. While cytokine response patterns are pivotal in mediating immune responses, they are also often dysregulated in sepsis and critical illness. We hypothesized that these immunological deficits, quantifiable through ex vivo whole blood stim
Externí odkaz:
https://doaj.org/article/4881966473c54550b9446356efd586c9
Autor:
Marie-France Forget, MD, MSc, Han Ting Wang, MD, MSc, Raphaelle Carignan, MD, Alexandre Dessureault, MD, Mathieu Gravel, MD, Jeanne Bienvenue, MD, Maude Bouchard, MD, Camille Durivage, MD, Richard Coveney, MBSI, Laveena Munshi, MD, MSc
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1107 (2024)
OBJECTIVES:. Older adults may be under-represented in critical care research, and results may not apply to this specific population. Our primary objective was to evaluate the prevalence of inclusion of older adults across critical care trials focused
Externí odkaz:
https://doaj.org/article/5cccca2f9c5e45d59ade74958d15733c
Autor:
Amirali Mirsajadi, BSc, Dustin Erickson, BSc, Soumya Alias, MSc, Logan Froese, PhD, Amanjyot Singh Sainbhi, BEng, Alwyn Gomez, MD, Raju Majumdar, BSc, Isuru Herath, BEng, Maggie Wilson, RN, MSc, Ryan Zarychanski, MD, MSc, Frederick A. Zeiler, MD, PhD, Asher A. Mendelson, MD, PhD, on behalf of the Microvasclar Monitoring in Circulatory Shock and Sepsis (MiMICSS) Investigators and the Canadian Critical Care Translational Biology Group, Asher Mendelson, Frederick Zeiler, Ryan Zarychanski, Sylvain Lother, Gloria Vazquez Grande, Olawale Ayilara, J Gordon Boyd, David Maslove, Stephanie Sibley
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1111 (2024)
IMPORTANCE:. Microvascular autoregulation (MA) maintains adequate tissue perfusion over a range of arterial blood pressure (ABP) and is frequently impaired in critical illness. MA has been studied in the brain to derive personalized hemodynamic targe
Externí odkaz:
https://doaj.org/article/990562b7dabf40779c301c365c943be5
Autor:
Shannon M. Fernando, MD, Alexandre Tran, MD, Karim Soliman, MD, Barbara Flynn, BScRN, Thomas Oommen, PharmD, Li Wenzhe, MD, Neill K.J. Adhikari, MDCM, Salmaan Kanji, PharmD, Andrew J.E. Seely, MD, PhD, Alison E. Fox-Robichaud, MD, Randy S. Wax, MD, FCCM, Deborah J. Cook, MD, François Lamontagne, MD, Bram Rochwerg, MD, FCCM
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1110 (2024)
OBJECTIVES:. Although clinicians may use methylene blue (MB) in refractory septic shock, the effect of MB on patient-important outcomes remains uncertain. We conducted a systematic review and meta-analysis to investigate the benefits and harms of MB
Externí odkaz:
https://doaj.org/article/ae52b02a10dd4d4f8d7e87e5cd01a8f6
Autor:
Michael L. Granda, MD, MS, Frances Tian, MD, Leila R. Zelnick, PhD, Pavan K. Bhatraju, MD, MSc, Julia Hallowell, BS, Mark M. Wurfel, MD, PhD, Andrew Hoofnagle, MD, PhD, Eric Morrell, MD, Bryan Kestenbaum, MD, MS
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1109 (2024)
IMPORTANCE:. COVID-19 may injure the kidney tubules via activation of inflammatory host responses and/or direct viral infiltration. Most studies of kidney injury in COVID-19 lacked contemporaneous controls or measured kidney biomarkers at a single ti
Externí odkaz:
https://doaj.org/article/fde3c87edc9344138e1b112383fd8ba4
Autor:
J. Charmaine Chan, BMedSc (Hons), MBCHB, MRCPCH, MMed (Paed), Anuradha P. Menon, MBBS, MRCPCH, MMed (Paed), Alexandre T. Rotta, MD, FCCM, Jonathan T.L. Choo, MBBS, FRCPCH, MPH, Christoph P. Hornik, MD, PhD, Jan Hau Lee, MBBS, MRCPH, MCI
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1114 (2024)
OBJECTIVES:. In critically ill children with severe sepsis, septic cardiomyopathy (SCM) denotes the subset of patients who have myocardial dysfunction with poor response to fluid and inotropic support, and higher mortality risk. The objective of this
Externí odkaz:
https://doaj.org/article/ee8b61a03ca54fc799278989b337e8b0
Autor:
Galen Royce-Nagel, MD, Mary Jarzebowski, MD, Pattrapun Wongsripuemtet, MD, Vijay Krishnamoorthy, MD, MPH, PhD, Matthew Fuller, MS, Tetsu Ohnuma, MD, MPH, PhD, Miriam Treggiari, MD, MPH, PhD, Miguel Yaport, MD, Julien Cobert, MD, Ethan Garrigan, MD, MPA, Raquel Bartz, MD, MMCi, MHA, Karthik Raghunathan, MD, MPH
Publikováno v:
Critical Care Explorations, Vol 6, Iss 7, p e1105 (2024)
OBJECTIVES:. To describe the utilization of early ketamine use among patients mechanically ventilated for COVID-19, and examine associations with in-hospital mortality and other clinical outcomes. DESIGN:. Retrospective cohort study. SETTING:. Six hu
Externí odkaz:
https://doaj.org/article/dc406ff71f9f4302829e038e61f5f31a