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Autor:
Hara Kang, Sunghwan Kim
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 550-554 (2013)
The platelet-derived growth factor (PDGF) signaling pathway isessential for inducing a dedifferentiated state of vascular smoothmuscle cells (VSMCs). Activation of PDGF inhibits smoothmuscle cell (SMC)-specific gene expression and increases the rateo
Externí odkaz:
https://doaj.org/article/0dc905d6f84f4d3f9b7557e59eedeb4a
Autor:
Ja-Hyun Baik
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 519-526 (2013)
Dopamine (DA) regulates emotional and motivationalbehavior through the mesolimbic dopaminergic pathway.Changes in DA signaling in mesolimbic neurotransmission arewidely believed to modify reward-related behaviors and aretherefore closely associated w
Externí odkaz:
https://doaj.org/article/6566b51757064567aedd21f584c8b197
Autor:
Ghislain Moussavou, Dong Hoon Kwak, Malg-Um Lim, Ji-Su Kim, Sun-Uk Kim, Kyu-Tae Chang, Young-Kug Choo
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 527-532 (2013)
Gangliosides are complex glycosphingolipids that are the majorcomponent of cytoplasmic cell membranes, and play a rolein the control of biological processes. Human mesenchymalstem cells (hMSCs) have received considerable attention as alternativesourc
Externí odkaz:
https://doaj.org/article/f460e86350e0490faf61ac5c36b544cd
Autor:
Eun Hee Ahn, Dae Won Kim, Min Jea Shin, Hyo Sang Jo, Seon Ae Eom, Duk-Soo Kim, Eun Young Park, Jong Hoon Park, Sung-Woo Cho, Jinseu Park, Won Sik Eum, Ora Son, Hyun Sook Hwang, Soo Young Choi
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 561-566 (2013)
We examined the ways in which fenobam could promote not onlythe transduction of PEP-1-FK506BP into cells and tissues but alsothe neuroprotective effect of PEP-1-FK506BP against ischemicdamage. Fenobam strongly enhanced the protective effect ofPEP-1-F
Externí odkaz:
https://doaj.org/article/de978395df6948f3a475068a1cf19afa
Autor:
Bo-Mi Hwang, Hee Suk Chae, Young-Ju Jeong, Young-Rae Lee, Eun-Mi Noh, Hyun Zo Youn, Sung Hoo Jung, Hong-Nu Yu, Eun Yong Chung, Jong-Suk Kim
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 533-538 (2013)
The expression of matrix metalloproteinases (MMPs) produced bycancer cells has been associated with the high potential ofmetastasis in several human carcinomas, including breast cancer.Several pieces of evidence demonstrate that protein tyrosinephosp
Externí odkaz:
https://doaj.org/article/e69d4e63bce2461dbb9275983166c626
Autor:
Won Kon Kim, Anna Park, Hye-Ryung Choi, Hyeyun Jung, Baek Soo Han, Sang Chul Lee, Kwang-Hee Bae
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 539-543 (2013)
There is a correlation between obesity and the amount ofbrown adipose tissue; however, the molecular mechanism ofbrown adipogenic differentiation has not been as extensivelystudied. In this study, we performed a protein tyrosinephosphatase (PTP) prof
Externí odkaz:
https://doaj.org/article/ef35a0303c9b4f5f8d17b01898bc38ee
Autor:
Jung Hoon Kang
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 555-560 (2013)
Acrolein is the most reactive aldehydic product of lipidperoxidation and is found to be elevated in the brain whenoxidative stress is high. The effects of acrolein on the structureand function of human Cu,Zn-superoxide dismutase (SOD) wereexamined. W
Externí odkaz:
https://doaj.org/article/c12dd1ffc4bd4d6e87b5f19b943da939
Autor:
Jong-Sup Bae, Alireza R. Rezaie
Publikováno v:
BMB Reports, Vol 46, Iss 11, Pp 544-549 (2013)
High mobility group box 1 (HMGB1) is involved in thepathogenesis of vascular diseases. Unlike activated protein C(APC), the activation of PAR-1 by thrombin is known to elicitproinflammatory responses. To determine whether the occupancyof EPCR by the
Externí odkaz:
https://doaj.org/article/306f9e2bf43241378f088353257743ed
Publikováno v:
BMB Reports, Vol 46, Iss 10, Pp 490-494 (2013)
The phosphatase and tensin homolog deleted on chromosome10 (PTEN) is a tumor-suppressing lipid phosphatase that isfrequently absent in breast tumors. Thus, the stability of PTENis essential for tumor prevention and therapy. The ubiquitinproteasomepat
Externí odkaz:
https://doaj.org/article/32fa4e91990a45c9a00988e75f00e929
Publikováno v:
BMB Reports, Vol 46, Iss 10, Pp 484-489 (2013)
Piperlonguminine (PL), an important component of Piperlongum fruits, is known to exhibit anti-hyperlipidemic, antiplateletand anti-melanogenic activities. Here, the anticoagulantactivities of PL were examined by monitoring activatedpartial-thrombopla
Externí odkaz:
https://doaj.org/article/1343df6963a64cdaa5f1f68c10d495e7