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pro vyhledávání: '"688"'
Publikováno v:
Biomedicines, Vol 12, Iss 3, p 688 (2024)
Background: The PACIFIC study showed that after radio-chemotherapy, patients with NSCLC derived a benefit in PFS and OS when treated with durvalumab. This effect was limited to patients with a PD-L1 expression of >1%, partly because the outcome in th
Externí odkaz:
https://doaj.org/article/132259ff97574f71b547049680204213
Publikováno v:
Biomedicines, Vol 11, Iss 3, p 688 (2023)
Liver kinase B1 (LKB1) is a tumor suppressor gene, the inactivation of which occurs frequently in different tumor types. However, whether LKB1 is associated with the clinical features of gastric cancer (GC) and regulating tumor immunity is unknown. I
Externí odkaz:
https://doaj.org/article/f782cad6148f4b32a17bab44d76ae835
Autor:
Graciela Andrei, Pierre Fiten, Marcela Krečmerová, Ghislain Opdenakker, Dimitrios Topalis, Robert Snoeck
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 580 (2022)
Despite the eradication of smallpox four decades ago, poxviruses continue to be a threat to humans and animals. The arsenal of anti-poxvirus agents is very limited and understanding mechanisms of resistance to agents targeting viral DNA polymerases i
Externí odkaz:
https://doaj.org/article/4b4928b02fcf4374883a31892f6f3596
Autor:
Andreas Nitsch, Silas Strakeljahn, Josephine M. Jacoby, Konrad F. Sieb, Alexander Mustea, Sander Bekeschus, Axel Ekkernkamp, Matthias B. Stope, Lyubomir Haralambiev
Publikováno v:
Biomedicines, Vol 10, Iss 3, p 688 (2022)
(1) Background: Chondrosarcoma (CS) is a malignant primary bone tumor with a cartilaginous origin. Its slow cell division and severely restricted vascularization are responsible for its poor responsiveness to chemotherapy and radiotherapy. The decisi
Externí odkaz:
https://doaj.org/article/209ac1cbd20042d9b25f899a4da6166f
Publikováno v:
Biomedicines, Vol 9, Iss 6, p 688 (2021)
We previously demonstrated that fetal allergen exposure caused T-helper 2 (Th2) cell sensitization. Although neonates are immunologically more mature than fetuses, asthmatic lungs were reportedly mitigated by neonatal allergen administration, mechani
Externí odkaz:
https://doaj.org/article/cd477c280aab4d0abd1b207d23452a11