Zobrazeno 1 - 10
of 86
pro vyhledávání: '"Igor Vujic"'
Autor:
Karoline Strobl, Jörg Klufa, Regina Jin, Lena Artner-Gent, Dana Krauß, Philipp Novoszel, Johanna Strobl, Georg Stary, Igor Vujic, Johannes Griss, Martin Holcmann, Matthias Farlik, Bernhard Homey, Maria Sibilia, Thomas Bauer
Publikováno v:
EMBO Molecular Medicine, Vol 16, Iss 12, Pp 3142-3168 (2024)
Abstract The hair follicle stem cell niche is an immune-privileged microenvironment, characterized by reduced antigen presentation, thus shielding against permanent immune-mediated tissue damage. In this study, we demonstrated the protective role of
Externí odkaz:
https://doaj.org/article/f4e87ecee1874448b2a1004628e97eb8
Autor:
Valentin Feichtenschlager, Linan Chen, Yixuan James Zheng, Wilson Ho, Martina Sanlorenzo, Igor Vujic, Eleanor Fewings, Albert Lee, Christopher Chen, Ciara Callanan, Kevin Lin, Tiange Qu, Dasha Hohlova, Marin Vujic, Yeonjoo Hwang, Kevin Lai, Stephanie Chen, Thuan Nguyen, Denise P Muñoz, Yoshinori Kohwi, Christian Posch, Adil Daud, Klemens Rappersberger, Terumi Kohwi-Shigematsu, Jean-Philippe Coppé, Susana Ortiz-Urda
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-21 (2024)
Abstract Finding effective therapeutic targets to treat NRAS-mutated melanoma remains a challenge. Long non-coding RNAs (lncRNAs) recently emerged as essential regulators of tumorigenesis. Using a discovery approach combining experimental models and
Externí odkaz:
https://doaj.org/article/d39bbf99048b49ce889263e2e9a46308
Publikováno v:
JEADV Clinical Practice, Vol 1, Iss 2, Pp 122-125 (2022)
Abstract Introduction We investigated whether governmental measures and lockdowns during the COVID‐19 pandemic had an impact on the number and histopathologic stages of melanoma. Methods The number and thickness (Breslow) of all diagnosed melanomas
Externí odkaz:
https://doaj.org/article/f13b2054acb14716b3776a51c504b454
Autor:
Constanze Jonak, Isolde Göttfried, Sylvia Perl-Convalexius, Barbara Gruber, Martina Schütz-Bergmayr, Igor Vujic, Wolfgang Weger, Nikolaus Schicher, Lydia Semlin, Margit Hemetsberger, Myriam Cordey, Paul Sator
Publikováno v:
Therapeutic Advances in Chronic Disease, Vol 14 (2023)
Background: Apremilast, an oral phosphodiesterase 4 inhibitor, is approved in the European Union for the treatment of moderate-to-severe chronic plaque psoriasis in adult patients refractory or contraindicated to or intolerant of other systemic thera
Externí odkaz:
https://doaj.org/article/cb9cca19100a4185b384cf5fd02d389c
Autor:
Thomas Graier, MD, Wolfgang Weger, MD, Paul-Gunther Sator, MD, Wolfgang Salmhofer, MD, Barbara Gruber, MD, Constanze Jonak, MD, Claudia Kölli, MD, Martina Schütz-Bergmayr, MD, Igor Vujic, MD, Gudrun Ratzinger, MD, Nina Häring, MD, Clemens Painsi, MD, PhD, Knut Prillinger, MD, Alexander Mlynek, MD, Hans Skvara, MD, Hannes Trattner, MD, Adrian Tanew, MD, Roland Lichem, MD, Christina Ellersdorfer, MD, Franz Legat, MD, Alexandra Gruber-Wackernagel, MD, Angelika Hofer, MD, Erich Schmiedberger, MSc, Wolfram Hoetzenecker, MD, PhD, Robert Müllegger, MD, Werner Saxinger, MD, Franz Quehenberger, PhD, Peter Wolf, MD
Publikováno v:
JAAD International, Vol 2, Iss , Pp 62-75 (2021)
Background: Little is known about the effectiveness and drug survival associated with apremilast under real-world conditions. Objective: To investigate the influence of patient and disease characteristics on drug survival associated with apremilast a
Externí odkaz:
https://doaj.org/article/648c20cfa91b403eb35f5ba5638ed651
Publikováno v:
PLoS ONE, Vol 10, Iss 4, p e0126988 (2015)
Externí odkaz:
https://doaj.org/article/3868d301175042acbf534069ccad6de1
Publikováno v:
PLoS ONE, Vol 9, Iss 9, p e107255 (2014)
PURPOSE:Genetically-targeted therapies are both promising and costly advances in the field of oncology. Several treatments for metastatic melanoma with a mutation in the BRAF gene have been approved. They extend life but are more expensive than the p
Externí odkaz:
https://doaj.org/article/07f9d429ffdf416597d3b5d0f9adbfd8
Autor:
Ramona Rotolo, Valeria Leuci, Chiara Donini, Federica Galvagno, Annamaria Massa, Maria Chiara De Santis, Serena Peirone, Giovanni Medico, Martina Sanlorenzo, Igor Vujic, Loretta Gammaitoni, Marco Basiricò, Luisella Righi, Chiara Riganti, Iris Chiara Salaroglio, Francesca Napoli, Fabrizio Tabbò, Annapaola Mariniello, Elisa Vigna, Chiara Modica, Lorenzo D’Ambrosio, Giovanni Grignani, Riccardo Taulli, Emilio Hirsch, Matteo Cereda, Massimo Aglietta, Giorgio Vittorio Scagliotti, Silvia Novello, Paolo Bironzo, Dario Sangiolo
Publikováno v:
Clinical Cancer Research. 29:621-634
Purpose: Antibodies against the lymphocyte PD-1 (aPD-1) receptor are cornerstone agents for advanced non–small cell lung cancer (NSCLC), based on their ability to restore the exhausted antitumor immune response. Our study reports a novel, lymphocyt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0bf52af420776a90fe006bc3d7d9c5ad
https://doi.org/10.1158/1078-0432.ccr-22-0761
https://doi.org/10.1158/1078-0432.ccr-22-0761
Autor:
Yixuan James, Zheng, Wilson, Ho, Martina, Sanlorenzo, Igor, Vujic, Adil, Daud, Alain, Algazi, Klemens, Rappersberger, Susana, Ortiz-Urda
Publikováno v:
Melanoma Research. 32:411-418
Immunosuppressive therapy is standard for the treatment of inflammatory diseases and for minimizing rejection in transplant patients. However, immunosuppressant drugs are associated with an increased risk of certain cancers. In particular, melanoma i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ba2716de9bcaef853b095907447f1154
https://doi.org/10.1097/cmr.0000000000000838
https://doi.org/10.1097/cmr.0000000000000838
Autor:
Dario Sangiolo, Paolo Bironzo, Silvia Novello, Giorgio Vittorio Scagliotti, Massimo Aglietta, Matteo Cereda, Emilio Hirsch, Riccardo Taulli, Giovanni Grignani, Lorenzo D’Ambrosio, Chiara Modica, Elisa Vigna, Annapaola Mariniello, Fabrizio Tabbò, Francesca Napoli, Iris Chiara Salaroglio, Chiara Riganti, Luisella Righi, Marco Basiricò, Loretta Gammaitoni, Igor Vujic, Martina Sanlorenzo, Giovanni Medico, Serena Peirone, Maria Chiara De Santis, Annamaria Massa, Federica Galvagno, Chiara Donini, Valeria Leuci, Ramona Rotolo
PD-L1/2 and phospho-p38 MAPK expression in NSCLC cells. Tumor membrane expression of PD-L1 and PD-L2 in NSCLC cell lines was intensely enhanced by treatment with Interferon γ (n=9, PD-L1 p=0.02, PD-L2 p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b6ec0bb3274f7c4bc99b140f2b8f43f
https://doi.org/10.1158/1078-0432.22489961.v1
https://doi.org/10.1158/1078-0432.22489961.v1
